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cimetidine and Hematemesis

cimetidine has been researched along with Hematemesis in 6 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Hematemesis: Vomiting of blood that is either fresh bright red, or older coffee-ground in character. It generally indicates bleeding of the UPPER GASTROINTESTINAL TRACT.

Research Excerpts

ExcerptRelevanceReference
"We studied the effects of tranexamic acid (an antifibrinolytic agent) and cimetidine on acute upper-gastrointestinal-tract bleeding in a double-blind randomized placebo-controlled trial in 775 patients with hematemesis or melena or both."5.05Cimetidine and tranexamic acid in the treatment of acute upper-gastrointestinal-tract bleeding. ( Atkinson, M; Barer, D; Coggon, D; Dronfield, M; Ellis, S; French, S; Henry, D; Langman, M; Ogilvie, A, 1983)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19905 (83.33)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Denavit, MF1
Guerin, J1
Caldera, R1
Rossier, A1
Barer, D1
Ogilvie, A1
Henry, D1
Dronfield, M1
Coggon, D1
French, S1
Ellis, S1
Atkinson, M1
Langman, M2
Spinka, R1
Honetz, N1
Jacob, H1
Brandt, LJ1
Berkowitz, D1
Bernstein, LH1
Katschinski, B1
Logan, R1
Davies, J1
Faulkner, G1
Pearson, J1
Borowitz, SM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of High Dose Infusion and Low Dose Bolus Intravenous Omeprazole for Treatment of Bleeding Ulcer With Adherent Clot[NCT02536989]Phase 440 participants (Actual)Interventional2009-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for cimetidine and Hematemesis

ArticleYear
Cimetidine and tranexamic acid in the treatment of acute upper-gastrointestinal-tract bleeding.
    The New England journal of medicine, 1983, Jun-30, Volume: 308, Issue:26

    Topics: Acute Disease; Aged; Cimetidine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Double-Blind

1983
Prognostic factors in upper gastrointestinal bleeding.
    Digestive diseases and sciences, 1994, Volume: 39, Issue:4

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cimetidine; Duodenal Ulcer; Female

1994

Other Studies

4 other studies available for cimetidine and Hematemesis

ArticleYear
[Duodenal ulcer in a newborn].
    Annales de pediatrie, 1978, Volume: 25, Issue:9

    Topics: Anti-Ulcer Agents; Blood Transfusion; Cesarean Section; Cimetidine; Combined Modality Therapy; Cryot

1978
[Acute granulocytopenia caused by cimetidine].
    Wiener medizinische Wochenschrift (1946), 1984, Mar-31, Volume: 134, Issue:6

    Topics: Acute Disease; Adult; Aged; Agranulocytosis; Cimetidine; Female; Hematemesis; Humans; Male; Middle A

1984
Massive hemorrhage from suture line ulceration: documentation by endoscopy.
    Gastrointestinal endoscopy, 1982, Volume: 28, Issue:3

    Topics: Cimetidine; Edema; Endoscopes; Endoscopy; Female; Gastrectomy; Hematemesis; Humans; Middle Aged; Sto

1982
Ulcerative esophagitis. A rare source of upper gastrointestinal bleeding in a neonate. Use of fiberoptic endoscopy for diagnosis.
    Clinical pediatrics, 1989, Volume: 28, Issue:2

    Topics: Cimetidine; Esophagitis; Esophagoscopy; Female; Fiber Optic Technology; Hematemesis; Humans; Infant,

1989