cimetidine has been researched along with Heart Failure in 2 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twelve patients with stable congestive heart failure and left ventricular dysfunction were enrolled in a double-blind, randomized crossover trial of famotidine, cimetidine and placebo to determine whether histamine type 2 (H2) antagonists adversely affect left ventricular systolic performance." | 9.07 | Effects of histamine type 2-receptor antagonists cimetidine and famotidine on left ventricular systolic function in chronic congestive heart failure. ( Jarboe, LA; Lee, RT; Solomon, SD; Wolfe, MM; Wolff, S, 1993) |
| "Twelve patients with stable congestive heart failure and left ventricular dysfunction were enrolled in a double-blind, randomized crossover trial of famotidine, cimetidine and placebo to determine whether histamine type 2 (H2) antagonists adversely affect left ventricular systolic performance." | 5.07 | Effects of histamine type 2-receptor antagonists cimetidine and famotidine on left ventricular systolic function in chronic congestive heart failure. ( Jarboe, LA; Lee, RT; Solomon, SD; Wolfe, MM; Wolff, S, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Solomon, SD | 1 |
| Wolff, S | 1 |
| Jarboe, LA | 1 |
| Wolfe, MM | 1 |
| Lee, RT | 1 |
| Engelhardt, D | 1 |
| Karl, R | 1 |
| Kolb, HJ | 1 |
| Inthorn, D | 1 |
| König, N | 1 |
| Büll, U | 1 |
| Hölzel, D | 1 |
2 trials available for cimetidine and Heart Failure
| Article | Year |
|---|---|
Effects of histamine type 2-receptor antagonists cimetidine and famotidine on left ventricular systolic function in chronic congestive heart failure.
Topics: Aged; Analysis of Variance; Chronic Disease; Cimetidine; Double-Blind Method; Echocardiography; Famo | 1993 |
[Comparison between cimetidine-pirenzepine and antacids for the prevention of stress hemorrhage in intensive care patients. A controlled clinical study on 125 patients].
Topics: Adult; Aged; Antacids; Benzodiazepinones; Chromium Radioisotopes; Cimetidine; Clinical Trials as Top | 1985 |