cimetidine has been researched along with Heart Disease, Ischemic in 2 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Surprisingly, the incidences of ischaemia- and reperfusion-induced arrhythmias were not reduced by ranitidine over an equivalent concentration range (0." | 3.69 | Protection by cimetidine, but not ranitidine, implies that H2 receptors do not mediate arrhythmogenesis in a rat model of regional ischaemia and reperfusion in vitro. ( Banning, MM; Curtis, MJ, 1995) |
| "Chloramphenicol is an inhibitor of mitochondrial protein synthesis and is also an inhibitor of a subset of cytochrome P450 monooxygenases (CYPs)." | 1.32 | Reduction of ischemia and reperfusion-induced myocardial damage by cytochrome P450 inhibitors. ( Gottlieb, RA; Granville, DJ; Gustafsson, AB; Huang, C; Sayen, MR; Takeuchi, C; Tashakkor, B; Wentworth, P; Yeager, M, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Granville, DJ | 1 |
| Tashakkor, B | 1 |
| Takeuchi, C | 1 |
| Gustafsson, AB | 1 |
| Huang, C | 1 |
| Sayen, MR | 1 |
| Wentworth, P | 1 |
| Yeager, M | 1 |
| Gottlieb, RA | 1 |
| Banning, MM | 1 |
| Curtis, MJ | 1 |
2 other studies available for cimetidine and Heart Disease, Ischemic
| Article | Year |
|---|---|
Reduction of ischemia and reperfusion-induced myocardial damage by cytochrome P450 inhibitors.
Topics: Animals; Chloramphenicol; Cimetidine; Creatine Kinase; Cytochrome P-450 Enzyme Inhibitors; Cytochrom | 2004 |
Protection by cimetidine, but not ranitidine, implies that H2 receptors do not mediate arrhythmogenesis in a rat model of regional ischaemia and reperfusion in vitro.
Topics: Animals; Arrhythmias, Cardiac; Cimetidine; Dose-Response Relationship, Drug; Electrocardiography; Hi | 1995 |