cimetidine has been researched along with Head and Neck Neoplasms in 4 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Head and Neck Neoplasms: Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A statistically significant increase in delayed hypersensitivity responses on repeated skin testing during cimetidine hydrochloride therapy was observed." | 1.27 | In vivo anergy reversal with cimetidine in patients with cancer. ( Eisele, D; Richtsmeier, WJ, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sprowl, JA | 1 |
| van Doorn, L | 1 |
| Hu, S | 1 |
| van Gerven, L | 1 |
| de Bruijn, P | 1 |
| Li, L | 1 |
| Gibson, AA | 1 |
| Mathijssen, RH | 1 |
| Sparreboom, A | 1 |
| Armitage, JO | 1 |
| Sidner, RD | 1 |
| Williamson, A | 1 |
| Miller, RH | 1 |
| Richtsmeier, WJ | 1 |
| Eisele, D | 1 |
4 other studies available for cimetidine and Head and Neck Neoplasms
| Article | Year |
|---|---|
Conjunctive therapy of cisplatin with the OCT2 inhibitor cimetidine: influence on antitumor efficacy and systemic clearance.
Topics: Adult; Aged; Animals; Antineoplastic Agents; Cell Line, Tumor; Cimetidine; Cisplatin; Drug Synergism | 2013 |
Antitumour effect of cimetidine.
Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Carcinoma; Carcinoma, Bronchogenic; Cimetidine; Female | 1979 |
Immunotherapy of head and neck cancer: an overview.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Neoplasm; Cimetidine; Head and Neck Neoplasms; Humans; | 1988 |
In vivo anergy reversal with cimetidine in patients with cancer.
Topics: Aged; Carcinoma, Squamous Cell; Cimetidine; Head and Neck Neoplasms; Humans; Hypersensitivity, Delay | 1986 |