cimetidine has been researched along with Hay Fever in 11 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Results showed that both antihistamines, applied topically of dosed orally, reduced sneezing even when significant increases of histamine concentration in nasal secretions were evidenced immediately after NAC." | 2.68 | The activity of recent anti-allergic drugs in the treatment of seasonal allergic rhinitis. ( Clement, P; De Waele, M; Smitz, J; Wang, D, 1996) |
| "We conclude that in subjects with bronchial asthma and marked bronchial hyperreactivity to ragweed antigen, there is a depression of gastric H2-histamine receptor function." | 2.66 | Suppression of gastric H2-receptor mediated function in patients with bronchial asthma and ragweed allergy. ( Ahmed, T; Gonzalez, H, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (72.73) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Peace, KE | 1 |
| Tsai, KT | 1 |
| Brooks, CD | 1 |
| Butler, D | 1 |
| Metzler, C | 1 |
| Carpenter, GB | 1 |
| Bunker-Soler, AL | 1 |
| Nelson, HS | 1 |
| Braibant, F | 1 |
| Mélon, J | 1 |
| Lecomte, J | 1 |
| Damas, J | 1 |
| Obel, AO | 1 |
| Ting, S | 1 |
| Zweiman, B | 1 |
| Lavker, RM | 1 |
| Dunsky, EH | 1 |
| Maderazo, EG | 1 |
| Albano, SD | 1 |
| Wang, D | 1 |
| Clement, P | 1 |
| Smitz, J | 1 |
| De Waele, M | 1 |
| Juliusson, S | 1 |
| Bende, M | 1 |
| Krasnowska, M | 1 |
| Liebhart, E | 1 |
| Wrzyszcz, M | 1 |
| Małolepszy, J | 1 |
| Gonzalez, H | 1 |
| Ahmed, T | 1 |
7 trials available for cimetidine and Hay Fever
| Article | Year |
|---|---|
Effect of H2 blockade in the challenged allergic nose.
Topics: Adolescent; Adult; Airway Resistance; Allergens; Cimetidine; Female; Guanidines; Histamine H2 Antago | 1982 |
Evaluation of combined H1- and H2-receptor blocking agents in the treatment of seasonal allergic rhinitis.
Topics: Adolescent; Adult; Chlorpheniramine; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Fema | 1983 |
Granulocyte migration abnormality in patients suffering from seasonal allergic rhinitis: failure of treatment with cimetidine.
Topics: Cell Movement; Chemotaxis; Cimetidine; Granulocytes; Histamine; Humans; Lysosomes; Micropore Filters | 1984 |
The activity of recent anti-allergic drugs in the treatment of seasonal allergic rhinitis.
Topics: Adult; Airway Resistance; Anti-Allergic Agents; Bronchodilator Agents; Budesonide; Cimetidine; Femal | 1996 |
Effect of systemically administered H1- and H2-receptor antagonists on nasal blood flow as measured with laser Doppler flowmetry in a provoked allergic reaction.
Topics: Adult; Allergens; Cimetidine; Cross-Over Studies; Double-Blind Method; Female; Histamine H1 Antagoni | 1996 |
[Effect of H1 and H2 receptor antagonists on the skin and bronchial reactivity in patients with hay fever].
Topics: Adult; Bronchial Provocation Tests; Cimetidine; Clinical Trials as Topic; Diphenhydramine; Drug Ther | 1986 |
Suppression of gastric H2-receptor mediated function in patients with bronchial asthma and ragweed allergy.
Topics: Adult; Asthma; Betazole; Bronchial Provocation Tests; Cimetidine; Female; Gastric Acid; Gastric Muco | 1986 |
4 other studies available for cimetidine and Hay Fever
| Article | Year |
|---|---|
Bivariate or composite plots of endpoints.
Topics: Airway Resistance; Anti-Allergic Agents; Anti-Ulcer Agents; Cimetidine; Clinical Trials as Topic; Da | 2009 |
[Histamine receptors and clinical expression of some anaphylactic reactions].
Topics: Anaphylaxis; Animals; Cimetidine; Drug Therapy, Combination; Guinea Pigs; Histamine H1 Antagonists; | 1984 |
Practical therapeutics: the use of histamine receptor antagonists in contemporary times.
Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Child; Cimetidine; Conjunctivitis, Allergic; Hista | 1984 |
Effect of cimetidine on exogenous histamine inhibition of histamine release in vivo.
Topics: Biopsy; Cimetidine; Guanidines; Histamine Antagonists; Histamine Release; Humans; Hypersensitivity; | 1983 |