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cimetidine and Goiter

cimetidine has been researched along with Goiter in 2 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Goiter: Enlargement of the THYROID GLAND that may increase from about 20 grams to hundreds of grams in human adults. Goiter is observed in individuals with normal thyroid function (euthyroidism), thyroid deficiency (HYPOTHYROIDISM), or hormone overproduction (HYPERTHYROIDISM). Goiter may be congenital or acquired, sporadic or endemic (GOITER, ENDEMIC).

Research Excerpts

ExcerptRelevanceReference
"Female patients with a simple goiter were pretreated on 2 occasions (at an interval of 4 wk) with po placebo or 400 mg cimetidine (Cim) (Group A, n = 10), or with placebo or 30 mg ranitidine (Ran) (Group B, n = 10), 90 and 150 min, respectively, prior to the po gelatin capsules containing [125I]levothyroxine ([125I]LT4)."5.07Effect of cimetidine and ranitidine on absorption of [125I]levothyroxine administered orally. ( Jonderko, G; Jonderko, K; Kotulska, A; Marcisz, C, 1992)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jonderko, G2
Jonderko, K1
Marcisz, C2
Kotulska, A2

Trials

1 trial available for cimetidine and Goiter

ArticleYear
Effect of cimetidine and ranitidine on absorption of [125I]levothyroxine administered orally.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1992, Volume: 13, Issue:5

    Topics: Absorption; Administration, Oral; Adult; Cimetidine; Double-Blind Method; Drug Interactions; Drug Th

1992

Other Studies

1 other study available for cimetidine and Goiter

ArticleYear
[Effect of cimetidine on radioisotope-labeled thyroxine absorption from the digestive tract].
    Polskie Archiwum Medycyny Wewnetrznej, 1988, Volume: 79, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Biological Availability; Cimetidine; Depression, Chemical;

1988