cimetidine has been researched along with Goiter in 2 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Goiter: Enlargement of the THYROID GLAND that may increase from about 20 grams to hundreds of grams in human adults. Goiter is observed in individuals with normal thyroid function (euthyroidism), thyroid deficiency (HYPOTHYROIDISM), or hormone overproduction (HYPERTHYROIDISM). Goiter may be congenital or acquired, sporadic or endemic (GOITER, ENDEMIC).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Female patients with a simple goiter were pretreated on 2 occasions (at an interval of 4 wk) with po placebo or 400 mg cimetidine (Cim) (Group A, n = 10), or with placebo or 30 mg ranitidine (Ran) (Group B, n = 10), 90 and 150 min, respectively, prior to the po gelatin capsules containing [125I]levothyroxine ([125I]LT4)." | 5.07 | Effect of cimetidine and ranitidine on absorption of [125I]levothyroxine administered orally. ( Jonderko, G; Jonderko, K; Kotulska, A; Marcisz, C, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jonderko, G | 2 |
| Jonderko, K | 1 |
| Marcisz, C | 2 |
| Kotulska, A | 2 |
1 trial available for cimetidine and Goiter
| Article | Year |
|---|---|
Effect of cimetidine and ranitidine on absorption of [125I]levothyroxine administered orally.
Topics: Absorption; Administration, Oral; Adult; Cimetidine; Double-Blind Method; Drug Interactions; Drug Th | 1992 |
1 other study available for cimetidine and Goiter
| Article | Year |
|---|---|
[Effect of cimetidine on radioisotope-labeled thyroxine absorption from the digestive tract].
Topics: Administration, Oral; Adolescent; Adult; Biological Availability; Cimetidine; Depression, Chemical; | 1988 |