cimetidine has been researched along with Glomerulonephritis, Membranous in 1 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Glomerulonephritis, Membranous: A type of glomerulonephritis that is characterized by the accumulation of immune deposits (COMPLEMENT MEMBRANE ATTACK COMPLEX) on the outer aspect of the GLOMERULAR BASEMENT MEMBRANE. It progresses from subepithelial dense deposits, to basement membrane reaction and eventual thickening of the basement membrane.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Passive Heymann nephritis is an experimental model that mimics membranous nephropathy in humans, wherein the glomerular epithelial cell (GEC) injury induced by complement C5b-9 leads to proteinuria." | 1.36 | Cytochrome P450 2B1 mediates complement-dependent sublytic injury in a model of membranous nephropathy. ( Arany, I; Baliga, R; Bigler, SA; Liu, H; Shah, SV; Tian, N; Waxman, DJ, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, H | 1 |
| Tian, N | 1 |
| Arany, I | 1 |
| Bigler, SA | 1 |
| Waxman, DJ | 1 |
| Shah, SV | 1 |
| Baliga, R | 1 |
1 other study available for cimetidine and Glomerulonephritis, Membranous
| Article | Year |
|---|---|
Cytochrome P450 2B1 mediates complement-dependent sublytic injury in a model of membranous nephropathy.
Topics: Animals; Antibodies; Cimetidine; Complement Membrane Attack Complex; Cytochrome P-450 CYP2B1; Diseas | 2010 |