Page last updated: 2024-10-25

cimetidine and Gastrinoma

cimetidine has been researched along with Gastrinoma in 3 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Gastrinoma: A GASTRIN-secreting neuroendocrine tumor of the non-beta ISLET CELLS, the GASTRIN-SECRETING CELLS. This type of tumor is primarily located in the PANCREAS or the DUODENUM. Majority of gastrinomas are malignant. They metastasize to the LIVER; LYMPH NODES; and BONE but rarely elsewhere. The presence of gastrinoma is one of three requirements to be met for identification of ZOLLINGER-ELLISON SYNDROME, which sometimes occurs in families with MULTIPLE ENDOCRINE NEOPLASIA TYPE 1; (MEN 1).

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pisegna, JR1
Norton, JA1
Slimak, GG1
Metz, DC1
Maton, PN1
Gardner, JD1
Jensen, RT1
Johnston, SR1
Wright, PL1
Luttwak, EM1
Saltz, NJ1

Trials

1 trial available for cimetidine and Gastrinoma

ArticleYear
Effects of curative gastrinoma resection on gastric secretory function and antisecretory drug requirement in the Zollinger-Ellison syndrome.
    Gastroenterology, 1992, Volume: 102, Issue:3

    Topics: Adult; Aged; Cimetidine; Dose-Response Relationship, Drug; Duodenal Neoplasms; Famotidine; Female; F

1992

Other Studies

2 other studies available for cimetidine and Gastrinoma

ArticleYear
Control of metastatic Zollinger-Ellison syndrome with high-dose H2-receptor antagonists.
    The British journal of clinical practice, 1990, Volume: 44, Issue:12

    Topics: Adult; Cimetidine; Gastrinoma; Humans; Liver Neoplasms; Male; Ranitidine; Zollinger-Ellison Syndrome

1990
The progressive Zollinger-Ellison syndrome in multiple endocrine neoplasia.
    Surgery, gynecology & obstetrics, 1988, Volume: 167, Issue:5

    Topics: Adult; Apudoma; Cimetidine; Follow-Up Studies; Gastrectomy; Gastrinoma; Humans; Male; Middle Aged; M

1988