cimetidine has been researched along with Gastric Diseases in 46 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Excerpt | Relevance | Reference |
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"Gastroesophageal reflux (GER) is a common episode in pediatric patients with severe motor and intellectual disabilities (SMID) and occasionally leads to a severe clinical state accompanied with nausea, hematemesis, melena, wheezing, pneumonia, anemia and/or failure to thrive." | 5.32 | Treatment of gastric hemorrhage by pulverized omeprazole and antacid--concomitant administration via a nasogastric tube. ( Kinoshita, E; Mukai, S; Ohtani, H; Sawada, Y; Yamaguchi, T, 2004) |
"The work describes the effects of cimetidine on stress-induced gizzard erosions (Experiment A) and the influence of the long-term application (42 days) of the same drug on weight gain and feed consumption during broiler fattening (Experiment B)." | 3.70 | Effects of cimetidine on broiler fattening and on stress-induced gizzard erosion in chicken. ( Bidin, Z; Culjak, K; Dzaja, P; Grabarević, Z; Mas, N; Mazija, H; Mikulec, Z; Njari, B; Perić, J; Serman, V; Simec, Z, 1999) |
"The effects of histamine antagonists, an anticholinergic agent and antacid on gizzard erosion (GE) induced by heated casein-histidine mixture (h-CH), histamine or starvation were examined." | 3.67 | Effects of histamine antagonists, an anticholinergic agent and antacid on gizzard erosions in broiler chicks. ( Miyazaki, S; Umemura, Y, 1987) |
"2 N sodium hydroxide, 25% sodium chloride, or boiling water produced extensive necrosis of the gastric mucosa." | 3.66 | Cytoprotection by prostaglandins in rats. Prevention of gastric necrosis produced by alcohol, HCl, NaOH, hypertonic NaCl, and thermal injury. ( Hanchar, AJ; Lancaster, C; Nezamis, JE; Robert, A, 1979) |
" An initial dose-response study in 48 subjects showed that 200- and 400-mg doses of cimetidine conferred a sufficient reduction in gastric mucosal injury to warrant further study." | 2.66 | Reduction of endoscopically assessed acute aspirin-induced gastric mucosal injury with cimetidine. ( Chapman, RC; Kimmey, MB; Saunders, DR; Silverstein, FE, 1987) |
"Aspirin effects were studied with and without previous treatment with cimetidine." | 2.64 | Protective effect of cimetidine on aspirin-induced gastric mucosal damage. ( Baskin, WN; Ivey, KJ; Krause, WJ; MacKercher, PA, 1977) |
" The use of cimetidina as an inhibitor of gastric secretion in a dosage of 1." | 2.36 | [Prophylaxis of acute gastroduodenal lesions in critically ill patients]. ( Bazzani, G; Dallaglio, JJ; Ferraina, PA; La Mura, R; Morel, CJ, 1981) |
"Gastroesophageal reflux (GER) is a common episode in pediatric patients with severe motor and intellectual disabilities (SMID) and occasionally leads to a severe clinical state accompanied with nausea, hematemesis, melena, wheezing, pneumonia, anemia and/or failure to thrive." | 1.32 | Treatment of gastric hemorrhage by pulverized omeprazole and antacid--concomitant administration via a nasogastric tube. ( Kinoshita, E; Mukai, S; Ohtani, H; Sawada, Y; Yamaguchi, T, 2004) |
"Flavone (1) was found to protect against ethanol-induced gastric damage in rats; however, it is known that certain compounds in the flavone class, including flavone itself, are inducers of hepatic drug metabolizing enzymes." | 1.29 | Synthesis and biological evaluation of substituted flavones as gastroprotective agents. ( Ares, JJ; Ems, BL; Kakodkar, SV; Kelm, GR; Kershaw, WC; Murray, PD; O'Brien, LM; Outt, PE; Randall, JL; Weisshaar, PS, 1995) |
"The risk of gastric cancer after vagotomy for benign gastric and duodenal disease was examined in a population based cohort of 7198 patients operated on during 1971-79 and followed up until 1988." | 1.29 | Gastric cancer risk after vagotomy. ( Ekbom, A; Lundegårdh, G; McLaughlin, JK; Nyrén, O, 1994) |
"Cimetidine was administered intravenously." | 1.28 | [Clinical report of cimetidine therapy for the prevention of the gastro-duodenal bleeding after the open heart surgery]. ( Kodama, T; Maeda, M; Muraki, H; Sasaki, S; Takeuchi, A, 1992) |
"Treatment with cimetidine (50 mg/kg, i." | 1.28 | Fluctuation of the mucosal hydroxyproline content in compound 48/80-induced gastric lesions in rats. ( Arisawa, T; Goto, H; Hase, S; Kawabe, Y; Kuroiwa, M; Nakazawa, S; Osada, T; Segawa, K; Tsuchida, T; Tsukamoto, Y, 1989) |
"Cimetidine was not effective in preventing the gastric damage." | 1.27 | Mucosal damage following electrical stimulation of the anterior cingulate cortex and pretreatment with atropine and cimetidine. ( Henke, PG, 1983) |
"Cimetidine was replaced with mycostatin and after four weeks of treatment, the ulcers healed completely in four patients." | 1.26 | Candidal infection of benign gastric ulcers in aged patients. ( Avidor, I; Kadish, U; Neeman, A, 1981) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 32 (69.57) | 18.7374 |
1990's | 10 (21.74) | 18.2507 |
2000's | 4 (8.70) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Ares, JJ | 1 |
Outt, PE | 1 |
Randall, JL | 1 |
Murray, PD | 1 |
Weisshaar, PS | 1 |
O'Brien, LM | 1 |
Ems, BL | 1 |
Kakodkar, SV | 1 |
Kelm, GR | 1 |
Kershaw, WC | 1 |
Tsai, JJ | 1 |
Lin, HJ | 1 |
Yamaguchi, T | 1 |
Mukai, S | 1 |
Kinoshita, E | 1 |
Ohtani, H | 1 |
Sawada, Y | 1 |
Melo, JR | 1 |
de Araújo, GK | 1 |
da Luz, MM | 1 |
da Conceição, SA | 1 |
Lisboa, FA | 1 |
Moraes-Santos, T | 1 |
Cunha-Melo, JR | 1 |
Raptopoulou-Gigi, M | 1 |
Boura, P | 1 |
Valcanos, N | 1 |
Goulis, G | 1 |
Henke, PG | 1 |
Morón, F | 1 |
Cuesta, E | 1 |
Bata, M | 1 |
Mózsik, G | 1 |
Modena, S | 1 |
Crudo, V | 1 |
Abrescia, F | 1 |
Baratella, M | 1 |
Bertrand, C | 1 |
Salvagno, R | 1 |
Vesentini, S | 1 |
Terano, A | 1 |
Matsumoto, K | 1 |
Motoki, T | 1 |
Murao, S | 1 |
Kamii, K | 1 |
Morel, CJ | 1 |
Ferraina, PA | 1 |
La Mura, R | 1 |
Dallaglio, JJ | 1 |
Bazzani, G | 1 |
Rothmund, M | 1 |
Wagner, PK | 1 |
Malesci, A | 1 |
Bonato, C | 1 |
Neeman, A | 1 |
Avidor, I | 1 |
Kadish, U | 1 |
Cipollini, F | 2 |
Massimi, AR | 1 |
Lamieri, C | 1 |
Altilia, F | 1 |
Grijalva, CV | 1 |
Deregnaucourt, J | 1 |
Code, CF | 1 |
Novin, D | 1 |
Kester, RR | 1 |
Paulshock, BZ | 1 |
Odonkor, P | 1 |
Mowat, C | 1 |
Himal, HS | 1 |
Atherton, JC | 1 |
Cockayne, A | 1 |
Balsitis, M | 1 |
Kirk, GE | 1 |
Hawkey, CJ | 1 |
Spiller, RC | 1 |
Lundegårdh, G | 1 |
Ekbom, A | 1 |
McLaughlin, JK | 1 |
Nyrén, O | 1 |
Murakami, K | 1 |
Okajima, K | 1 |
Uchiba, M | 1 |
Harada, N | 1 |
Liu, W | 1 |
Okabe, H | 1 |
Takatsuki, K | 1 |
Kitano, M | 1 |
Wada, K | 1 |
Kamisaki, Y | 1 |
Nakamoto, K | 1 |
Kishimoto, Y | 1 |
Kawasaki, H | 1 |
Itoh, T | 1 |
Grabarević, Z | 1 |
Dzaja, P | 1 |
Perić, J | 1 |
Serman, V | 1 |
Bidin, Z | 1 |
Mazija, H | 1 |
Mas, N | 1 |
Mikulec, Z | 1 |
Culjak, K | 1 |
Simec, Z | 1 |
Njari, B | 1 |
Bilic, I | 1 |
Zoricic, I | 1 |
Anic, T | 1 |
Separovic, J | 1 |
Stancic-Rokotov, D | 1 |
Mikus, D | 1 |
Buljat, G | 1 |
Ivankovic, D | 1 |
Aralica, G | 1 |
Prkacin, I | 1 |
Perovic, D | 1 |
Mise, S | 1 |
Rotkvic, I | 1 |
Petek, M | 1 |
Rucman, R | 1 |
Seiwerth, S | 1 |
Sikiric, P | 1 |
MacKercher, PA | 1 |
Ivey, KJ | 1 |
Baskin, WN | 1 |
Krause, WJ | 1 |
Cheung, LY | 1 |
Porterfield, G | 1 |
Robert, A | 1 |
Nezamis, JE | 1 |
Lancaster, C | 1 |
Hanchar, AJ | 1 |
Simon, B | 1 |
Kather, H | 1 |
Maeda, M | 1 |
Muraki, H | 1 |
Kodama, T | 1 |
Sasaki, S | 1 |
Takeuchi, A | 1 |
Kappstein, I | 1 |
Schulgen, G | 1 |
Friedrich, T | 1 |
Hellinger, P | 1 |
Benzing, A | 1 |
Geiger, K | 1 |
Daschner, FD | 1 |
Laine, L | 1 |
Lanza, FL | 1 |
Graham, DY | 1 |
Davis, RE | 1 |
Rack, MF | 1 |
Arisawa, T | 1 |
Nakazawa, S | 1 |
Segawa, K | 1 |
Tsukamoto, Y | 1 |
Goto, H | 1 |
Hase, S | 1 |
Osada, T | 1 |
Kawabe, Y | 1 |
Kuroiwa, M | 1 |
Tsuchida, T | 1 |
Di Febo, G | 1 |
Miglioli, M | 1 |
Calò, G | 1 |
Biasco, G | 1 |
Luzza, F | 1 |
Gizzi, G | 1 |
Rossi, A | 1 |
Barbara, L | 1 |
Agrawal, NM | 1 |
Godiwala, T | 1 |
Arimura, A | 1 |
Groot, K | 1 |
Dajani, E | 1 |
Streett, CS | 1 |
Robertson, JL | 1 |
Crissman, JW | 1 |
Hogan, DL | 1 |
Thomas, FJ | 1 |
Isenberg, JI | 1 |
Kimmey, MB | 1 |
Silverstein, FE | 1 |
Saunders, DR | 1 |
Chapman, RC | 1 |
Florent, C | 1 |
Vidon, N | 1 |
Flourié, B | 1 |
Carmantrand, A | 1 |
Zerbani, A | 1 |
Maurel, M | 1 |
Bernier, JJ | 1 |
Vandenplas, Y | 1 |
Sacre, L | 1 |
Miyazaki, S | 1 |
Umemura, Y | 1 |
Townsend, CM | 1 |
Thompson, JC | 1 |
Peura, DA | 1 |
Johnson, LF | 1 |
Pulay, I | 1 |
Farkas, A | 1 |
Máthé, Z | 1 |
Máthé, G | 1 |
Berstad, A | 1 |
Nesland, A | 1 |
Takeuchi, K | 1 |
Ohtsuki, H | 1 |
Okabe, S | 2 |
Hara, N | 1 |
2 reviews available for cimetidine and Gastric Diseases
Article | Year |
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[Prophylaxis of acute gastroduodenal lesions in critically ill patients].
Topics: Acute Disease; Cimetidine; Female; Gastric Acid; Gastric Mucosa; Gastrointestinal Hemorrhage; Guanid | 1981 |
Prepyloric erosions and related changes.
Topics: Cimetidine; Female; Gastric Acid; Gastric Mucosa; Humans; Male; Middle Aged; Pylorus; Stomach Diseas | 1985 |
9 trials available for cimetidine and Gastric Diseases
Article | Year |
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[Effect of cimetidine and secretin on acute bleedings from gastroduodenal ulcers and erosions: a prospective study (author's transl)].
Topics: Cimetidine; Guanidines; Humans; Peptic Ulcer Hemorrhage; Prospective Studies; Recurrence; Secretin; | 1982 |
Protective effect of cimetidine on aspirin-induced gastric mucosal damage.
Topics: Adult; Aspirin; Cimetidine; Gastric Mucosa; Guanidines; Humans; Hydrogen-Ion Concentration; Male; So | 1977 |
NSAID-induced gastroduodenal injury: what's the score?
Topics: Adult; Cimetidine; Duodenal Diseases; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Middle Ag | 1991 |
Endoscopic comparison of cimetidine and sucralfate for prevention of naproxen-induced acute gastroduodenal injury. Effect of scoring method.
Topics: Adult; Cimetidine; Duodenal Diseases; Duodenal Ulcer; Female; Gastric Mucosa; Gastrointestinal Hemor | 1990 |
Protective effects against alcohol insult: does somatostatin play any role?
Topics: Adult; Alprostadil; Anti-Ulcer Agents; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Et | 1988 |
Cimetidine decreases aspirin-induced gastric mucosal damage in humans.
Topics: Adult; Aspirin; Cimetidine; Double-Blind Method; Female; Gastric Mucosa; Gastroscopy; Humans; Male; | 1987 |
Reduction of endoscopically assessed acute aspirin-induced gastric mucosal injury with cimetidine.
Topics: Acute Disease; Adolescent; Adult; Aspirin; Cimetidine; Clinical Trials as Topic; Dose-Response Relat | 1987 |
The use of cimetidine in newborns.
Topics: Bottle Feeding; Cimetidine; Gastrointestinal Hemorrhage; Humans; Infant, Newborn; Random Allocation; | 1987 |
Cimetidine for prevention and treatment of gastroduodenal mucosal lesions in patients in an intensive care unit.
Topics: Adult; Aged; Blood Transfusion; Cimetidine; Critical Care; Double-Blind Method; Duodenal Diseases; D | 1985 |
35 other studies available for cimetidine and Gastric Diseases
Article | Year |
---|---|
Synthesis and biological evaluation of substituted flavones as gastroprotective agents.
Topics: Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Enzyme Induction; Ethanol; Flavono | 1995 |
Intermittent intravenous pantoprazole and continuous cimetidine infusion: effect on gastric pH control in critically ill patients at risk of developing stressed related mucosal disease.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Cimetidine; Critical Illness; Gastric Mu | 2008 |
Treatment of gastric hemorrhage by pulverized omeprazole and antacid--concomitant administration via a nasogastric tube.
Topics: Adolescent; Antacids; Anti-Ulcer Agents; Cimetidine; Drug Therapy, Combination; Gastroesophageal Ref | 2004 |
Effect of acid secretion blockade on acute gastric mucosal lesions induced by Tityus serrulatus scorpion toxin in anaesthetized rats.
Topics: Acute Disease; Anesthesia; Animals; Atropine; Cimetidine; Dose-Response Relationship, Drug; Drug Ant | 2006 |
Lymphocyte subpopulations in gastric disease; effect of histamine and cimetidine on immunoregulatory T cell subsets.
Topics: Cimetidine; Duodenal Ulcer; Gastritis; Histamine; Humans; In Vitro Techniques; Middle Aged; Stomach | 1984 |
Mucosal damage following electrical stimulation of the anterior cingulate cortex and pretreatment with atropine and cimetidine.
Topics: Animals; Atropine; Brain Mapping; Cimetidine; Electric Stimulation; Gastric Mucosa; Gyrus Cinguli; M | 1983 |
Cytoprotecting-effect of cimetidine: experimental evidence in the rat gastric mucosal lesions induced by intragastric administration of necrotizing agents.
Topics: Animals; Cimetidine; Ethanol; Female; Gastric Acid; Gastric Mucosa; Hydrochloric Acid; Male; Rats; S | 1983 |
[Esophago-gastro-enteric manifestations of scleroderma. Apropos of a clinical case].
Topics: Adult; Cimetidine; Diagnosis, Differential; Duodenal Ulcer; Esophageal Diseases; Gastroesophageal Re | 1983 |
[Effect of prostaglandin E2, cimetidine and geranyl-geranyl-acetone on rat gastric mucosal damage (author's transl)].
Topics: Animals; Cimetidine; Dinoprostone; Diterpenes; Gastric Mucosa; Guanidines; Male; Prostaglandins E; R | 1981 |
[Smoke and stomach diseases].
Topics: Antacids; Cimetidine; Duodenal Ulcer; Female; Humans; Lung Neoplasms; Male; Pancreatic Neoplasms; Pe | 1982 |
Candidal infection of benign gastric ulcers in aged patients.
Topics: Aged; Candidiasis; Cimetidine; Female; Humans; Male; Middle Aged; Nystatin; Stomach Diseases; Stomac | 1981 |
[Solitary mycoses of the stomach. Incidence, endoscopic aspects and clinical significance].
Topics: Adult; Aged; Cimetidine; Endoscopy; Female; Gastrectomy; Gastritis, Atrophic; Humans; Male; Middle A | 1981 |
Gastric mucosal damage in rats induced by lateral hypothalamic lesions: protection by propantheline, cimetidine, and vagotomy.
Topics: Animals; Cimetidine; Gastric Mucosa; Guanidines; Hypothalamus; Male; Propantheline; Rats; Stomach Di | 1980 |
Cimetidine: chronicle of a new drug.
Topics: Cimetidine; Guanidines; Humans; Peptic Ulcer; Stomach Diseases; Zollinger-Ellison Syndrome | 1980 |
Prevention of sepsis-induced gastric lesions in dogs by cimetidine via inhibition of gastric secretion and by prostaglandin via cytoprotection.
Topics: Animals; Bacterial Infections; Cimetidine; Dogs; Gastric Acid; Guanidines; Peritonitis; Prostaglandi | 1981 |
Detection of the intragastric sites at which Helicobacter pylori evades treatment with amoxycillin and cimetidine.
Topics: Adult; Aged; Amoxicillin; Cimetidine; Female; Gastric Fundus; Helicobacter Infections; Helicobacter | 1995 |
Gastric cancer risk after vagotomy.
Topics: Aged; Cimetidine; Cohort Studies; Duodenal Diseases; Female; Humans; Male; Medical Record Linkage; M | 1994 |
Role of granulocyte elastase in indomethacin-induced gastric mucosal lesion formation in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cephalosporins; Cimetidine; Gastric Mucosa; Glycin | 1997 |
Effects of cimetidine on acute gastric mucosal injury induced by ischemia-reperfusion in rats.
Topics: Animals; Anti-Ulcer Agents; Cimetidine; Erythrocyte Membrane; Famotidine; Gastric Mucosa; Histamine | 1997 |
Effects of cimetidine on broiler fattening and on stress-induced gizzard erosion in chicken.
Topics: Animals; Body Weight; Bursa of Fabricius; Chickens; Cimetidine; Female; Gizzard, Avian; Histamine H2 | 1999 |
Haloperidol-stomach lesions attenuation by pentadecapeptide BPC 157, omeprazole, bromocriptine, but not atropine, lansoprazole, pantoprazole, ranitidine, cimetidine and misoprostol in mice.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Atropine; Benzimidazoles; Bromo | 2001 |
Is histamine a mediator in bile-induced gastric mucosal injury?
Topics: Animals; Bile; Cimetidine; Disease Models, Animal; Dogs; Gastric Mucosa; Histamine; Histamine Releas | 1978 |
Cytoprotection by prostaglandins in rats. Prevention of gastric necrosis produced by alcohol, HCl, NaOH, hypertonic NaCl, and thermal injury.
Topics: Animals; Antacids; Burns; Cimetidine; Ethanol; Female; Gastric Juice; Gastric Mucosa; Hydrochloric A | 1979 |
Rational basis for the application of cimetidine in the therapy of human gastric hypersecretion.
Topics: Adenylyl Cyclases; Cimetidine; Gastric Mucosa; Guanidines; Histamine; Humans; In Vitro Techniques; S | 1977 |
[Clinical report of cimetidine therapy for the prevention of the gastro-duodenal bleeding after the open heart surgery].
Topics: Adolescent; Adult; Child; Cimetidine; Drug Administration Schedule; Drug Evaluation; Duodenal Diseas | 1992 |
Incidence of pneumonia in mechanically ventilated patients treated with sucralfate or cimetidine as prophylaxis for stress bleeding: bacterial colonization of the stomach.
Topics: Adult; Bacterial Infections; Cimetidine; Colony Count, Microbial; Cross Infection; Female; Gastric A | 1991 |
Fluctuation of the mucosal hydroxyproline content in compound 48/80-induced gastric lesions in rats.
Topics: Animals; Cimetidine; Gastric Mucosa; Hydroxyproline; Male; p-Methoxy-N-methylphenethylamine; Rats; R | 1989 |
Candida albicans infection of gastric ulcer frequency and correlation with medical treatment. Results of a multicenter study.
Topics: Candida; Candidiasis; Cimetidine; Geotrichosis; Histamine H2 Antagonists; Humans; Mycoses; Prospecti | 1985 |
Morphologic stomach findings in rats and mice treated with the H2 receptor antagonists, ICI 125,211 and ICI 162,846.
Topics: Animals; Carcinogens; Cimetidine; Female; Histamine H2 Antagonists; Male; Mice; Mice, Inbred Strains | 1988 |
Gastric clearance of alpha-1-antitrypsin under cimetidine perfusion. New test to detect protein-losing gastropathy?
Topics: Adult; alpha 1-Antitrypsin; Blood Proteins; Chromium Radioisotopes; Cimetidine; Feces; Female; Gastr | 1986 |
Effects of histamine antagonists, an anticholinergic agent and antacid on gizzard erosions in broiler chicks.
Topics: Animals; Antacids; Caseins; Chickens; Cimetidine; Diphenhydramine; Gizzard, Avian; Histamine; Histam | 1987 |
Gastrinoma.
Topics: Cimetidine; Diagnosis, Differential; Female; Gastrectomy; Gastric Juice; Gastrins; Male; Methods; Ra | 1986 |
Effect of cimetidine (Histodil) injection in upper gastro-intestinal haemorrhage.
Topics: Adult; Aged; Aged, 80 and over; Cimetidine; Duodenal Diseases; Esophageal Diseases; Female; Gastroin | 1985 |
Pathogenesis of compound 48/80-induced gastric lesions in rats.
Topics: Animals; Blood Pressure; Chromones; Cimetidine; Cyproheptadine; Drug Interactions; Gastric Mucosa; H | 1986 |
[Effects of gefarnate on acute gastric lesions in rats].
Topics: Acute Disease; Animals; Aspirin; Cimetidine; Ethanol; Gefarnate; Male; Rats; Rats, Inbred Strains; S | 1985 |