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cimetidine and Galactorrhea

cimetidine has been researched along with Galactorrhea in 10 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Galactorrhea: Excessive or inappropriate LACTATION in females or males, and not necessarily related to PREGNANCY. Galactorrhea can occur either unilaterally or bilaterally, and be profuse or sparse. Its most common cause is HYPERPROLACTINEMIA.

Research Excerpts

ExcerptRelevanceReference
"Various breast abnormalities have been described in patients treated chronically with cimetidine, but galactorrhea has been reported only twice in the medical literature."7.67Cimetidine-induced galactorrhea. ( Dhar, R; Ehrinpreis, MN; Narula, A, 1989)
" e) The gynaecomastia, galactorrhoea, amenorrhoea and impotence--reported only after long-term cimetidine treatment--can probably be attributed to the specific antiandrogen receptor property of CMT."4.77[Dysfunction of the hypothalamo-hypophyseal-gonadal axis induced by histamine H2 antagonists. Review of the literature and personal observations]. ( Biagi, P; Milani, G, 1985)
"Various breast abnormalities have been described in patients treated chronically with cimetidine, but galactorrhea has been reported only twice in the medical literature."3.67Cimetidine-induced galactorrhea. ( Dhar, R; Ehrinpreis, MN; Narula, A, 1989)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-199010 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
De Martiis, M1
D'Ottavi, R1
Patrizi, P1
Bacchi Modena, A1
Vadora, E1
Fiaschetti, D1
Micucci, G1
Lombardozzi, L1
de Rosa, G1
Gulino, A1
de Rosa, E1
Satta, MA1
Aiello, A1
Makhoul, O1
Pasargiklian, E1
Voget, E1
Schollmeyer, P1
Bezuidenhout, DJ1
Ehrinpreis, MN1
Dhar, R1
Narula, A1
Estrada Rodríguez, M1
Izquierdo de la Rosa, H1
González Peláez, J1
Arredondo Bruce, A1
Nucete, HJ1
Bravo, M1
Somoza, B1
Jauhari, J1
Biagi, P1
Milani, G1

Reviews

2 reviews available for cimetidine and Galactorrhea

ArticleYear
[The therapeutic importance of cimetidine (Tagamet) (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1978, Nov-03, Volume: 120, Issue:44

    Topics: Adult; Cimetidine; Diarrhea; Female; Galactorrhea; Gastritis; Guanidines; Gynecomastia; Headache; Hu

1978
[Dysfunction of the hypothalamo-hypophyseal-gonadal axis induced by histamine H2 antagonists. Review of the literature and personal observations].
    Minerva medica, 1985, Mar-24, Volume: 76, Issue:12

    Topics: Amenorrhea; Androgens; Cimetidine; Erectile Dysfunction; Female; Follicle Stimulating Hormone; Galac

1985

Other Studies

8 other studies available for cimetidine and Galactorrhea

ArticleYear
[Relationship between cimetidine and prolactin].
    La Clinica terapeutica, 1982, Mar-15, Volume: 100, Issue:5

    Topics: Breast Diseases; Cimetidine; Female; Galactorrhea; Guanidines; Gynecomastia; Humans; Male; Pregnancy

1982
[Role of H2 receptors in controlling prolactin release. Decreased response to cimetidine in patients with prolactin-secreting adenoma and idiopathic hyperprolactinemia].
    Minerva ginecologica, 1984, Volume: 36, Issue:6

    Topics: Adenoma; Adult; Cimetidine; Female; Galactorrhea; Humans; Pituitary Neoplasms; Pregnancy; Prolactin;

1984
[Effects of citicholine on pituitary gland function in normal subjects and in cases of idiopathic galactorrhea].
    La Clinica terapeutica, 1980, Aug-31, Volume: 94, Issue:4

    Topics: Adolescent; Adult; Choline; Cimetidine; Cytidine Diphosphate Choline; Female; Galactorrhea; Growth H

1980
[Gynaecomastia during treatment with cimetidine].
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1978, Aug-12, Volume: 54, Issue:7

    Topics: Cimetidine; Female; Galactorrhea; Guanidines; Gynecomastia; Humans; Male; Middle Aged; Pregnancy

1978
Cimetidine-induced galactorrhea.
    The American journal of gastroenterology, 1989, Volume: 84, Issue:5

    Topics: Cimetidine; Female; Galactorrhea; Humans; Lactation Disorders; Middle Aged

1989
[Adverse clinico-humoral manifestations in ulcer patients treated with cimetidine. Our experience in 488 patients].
    Revista espanola de las enfermedades del aparato digestivo, 1988, Volume: 73, Issue:6

    Topics: Cimetidine; Drug Eruptions; Duodenal Ulcer; Erectile Dysfunction; Galactorrhea; Gastrointestinal Dis

1988
[Prolactin: a function test with cimetidine].
    Acta cientifica venezolana, 1986, Volume: 37, Issue:2

    Topics: Adult; Cimetidine; Female; Galactorrhea; Humans; Injections, Intravenous; Lactation Disorders; Pregn

1986
Gynaecomastia, galactorrhoea and impotence--the uncommon side effects of cimetidine therapy.
    The Journal of the Association of Physicians of India, 1987, Volume: 35, Issue:6

    Topics: Adult; Cimetidine; Erectile Dysfunction; Female; Galactorrhea; Gynecomastia; Humans; Lactation Disor

1987