cimetidine has been researched along with Flushing in 5 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Flushing: A transient reddening of the face that may be due to fever, certain drugs, exertion, or stress.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mesenteric traction syndrome is described as sudden tachycardia, hypotension and flush." | 2.70 | Histamine release in mesenteric traction syndrome during abdominal aortic aneurysm surgery: prophylaxis with H1 and H2 antihistamines. ( Celik, I; Duda, D; Lorenz, W, 2002) |
| "Diphenhydramine was similar to placebo in its effect on the flushing reaction." | 2.66 | Histamine receptor antagonism of intolerance to alcohol in the Oriental population. ( Anand, MM; Gabrielli, WF; Goodwin, DW; Hall, TB; Jones, FC; Miller, NS; Pardo, MP, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Duda, D | 1 |
| Lorenz, W | 1 |
| Celik, I | 1 |
| Shuster, J | 1 |
| Yarbrough, JA | 1 |
| Moffitt, JE | 1 |
| Brown, DA | 1 |
| Stafford, CT | 1 |
| Miller, NS | 2 |
| Goodwin, DW | 2 |
| Jones, FC | 2 |
| Gabrielli, WF | 2 |
| Pardo, MP | 2 |
| Anand, MM | 2 |
| Hall, TB | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Treatment of Asian Flushing Syndrome With Topical Alpha Agonists[NCT03497442] | Early Phase 1 | 20 participants (Actual) | Interventional | 2018-07-12 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for cimetidine and Flushing
| Article | Year |
|---|---|
Histamine release in mesenteric traction syndrome during abdominal aortic aneurysm surgery: prophylaxis with H1 and H2 antihistamines.
Topics: Aortic Aneurysm, Abdominal; Blood Pressure; Cardiac Output; Cimetidine; Dimethindene; Double-Blind M | 2002 |
Antihistamine blockade of alcohol-induced flushing in orientals.
Topics: Adolescent; Adult; Alcoholism; Asian People; Blood Pressure; Cimetidine; Diphenhydramine; Ethanol; F | 1988 |
Histamine receptor antagonism of intolerance to alcohol in the Oriental population.
Topics: Adolescent; Adult; Asian People; Blood Pressure; Cimetidine; Diphenhydramine; Drug Synergism; Ethano | 1987 |
2 other studies available for cimetidine and Flushing
| Article | Year |
|---|---|
Cimetidine and hot flashes.
Topics: Adult; Anti-Ulcer Agents; Cimetidine; Flushing; Humans; Kidney Failure, Chronic; Male; Nonprescripti | 2000 |
Cimetidine in the treatment of refractory anaphylaxis.
Topics: Anaphylaxis; Cefuroxime; Cimetidine; Drug Hypersensitivity; Female; Flushing; Humans; Hypotension; I | 1989 |