cimetidine has been researched along with Esophagitis in 38 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Esophagitis: INFLAMMATION, acute or chronic, of the ESOPHAGUS caused by BACTERIA, chemicals, or TRAUMA.
Excerpt | Relevance | Reference |
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"Previous studies have demonstrated greater efficacy for omeprazole compared with cimetidine in patients with endoscopically verified oesophagitis, but excluded the substantial group of gastro-oesophageal reflux disease (GERD) patients with reflux symptoms but without endoscopic abnormality." | 9.08 | Omeprazole is more effective than cimetidine for the relief of all grades of gastro-oesophageal reflux disease-associated heartburn, irrespective of the presence or absence of endoscopic oesophagitis. ( Axon, AT; Bate, CM; Emmas, CE; Green, JR; Murray, FE; Taylor, MD; Tildesley, G, 1997) |
" is more effective than cimetidine 800 mg nocte in the prevention of recurrence of GERD-associated heartburn and the occurrence of underlying oesophagitis." | 9.08 | Omeprazole is more effective than cimetidine in the prevention of recurrence of GERD-associated heartburn and the occurrence of underlying oesophagitis. ( Axon, AT; Bate, CM; Emmas, C; Green, JR; Murrays, FE; Owen, SM; Taylor, MD; Tildesley, G, 1998) |
"Double-blind randomized controlled trials in single subjects (N of 1 RCTs) have demonstrated a beneficial symptomatic effect of cimetidine in reflux- or ulcer-like non-ulcer dyspepsia (NUD)." | 9.07 | Cimetidine on-demand in dyspepsia. Experience with randomized controlled single-subject trials. ( Dybdahl, J; Fosstvedt, D; Johannessen, T; Kleveland, PM; Kristensen, P; Løge, I; Petersen, H, 1992) |
"Before endoscopy a double-blind, randomized, controlled, single-subject trial comparing the symptomatic effect of 1-day treatment periods with cimetidine and placebo was conducted in patients with dyspepsia." | 9.07 | The symptomatic effect of 1-day treatment periods with cimetidine in dyspepsia. Combined results from randomized, controlled, single-subject trials. ( Dybdahl, J; Fosstvedt, D; Johannessen, T; Kleveland, PM; Kristensen, P; Løge, I; Petersen, H, 1991) |
"In a double-blind, randomized, comparative trial of the prokinetic drug cisapride and the H2-blocker cimetidine, mucosal healing and changes in symptoms of gastroesophageal reflux were evaluated in patients with erosive reflux esophagitis." | 9.06 | Double-blind comparison of cisapride and cimetidine in treatment of reflux esophagitis. ( Evreux, M; Filoche, B; Fournet, J; Fraitag, B; Galmiche, JP; Soule, JC; Vitaux, J; Zeitoun, P, 1990) |
"In a Canadian multicenter trial, a new dosing regimen of cimetidine (Tagamet)-600 mg given twice a day-was compared with the standard regimen of 300 mg four times a day in 118 evaluable patients with endoscopically proved esophagitis." | 9.05 | Cimetidine therapy for gastroesophageal reflux disease. ( Archambault, AP; Cleator, IG; Farley, A; Hershfield, NB; Navert, H; Prokipchuk, EJ; Thomson, AB, 1985) |
"Forty five patients with refractory oesophagitis, defined as persisting erosive changes or ulceration despite a minimum of three months' treatment with cimetidine 3." | 7.68 | Omeprazole in the treatment of erosive oesophagitis refractory to high dose cimetidine and ranitidine. ( Bardhan, KD; Carroll, NJ; Daly, MJ; Dhande, DS; Hinchliffe, RF; Jones, RB; Morris, P; Thompson, M, 1990) |
"The potential mucosal protective effects of a liquid sucralfate preparation and the histamine (H2)-antagonist cimetidine on acid-induced esophagitis were studied." | 7.67 | Comparison of potential cytoprotective action of sucralfate and cimetidine. Studies with experimental feline esophagitis. ( Castell, DO; Clark, S; Geisinger, KR; Katz, PO; Wu, WC, 1987) |
"We conducted a double-blind study to compare the effectiveness of oral bethanechol chloride or cimetidine in treating reflux esophagitis to evaluate the drugs' effects on the symptoms of esophagitis and its verification by endoscopy." | 7.66 | Bethanechol or cimetidine in the treatment of symptomatic reflux esophagitis: a double-blind control study. ( Chey, WY; Hamilton, D; Nadelson, N; Shak, A; Thanik, K, 1982) |
"Cimetidine treatment was successful for seven years but dose reduction was followed by intractable hemorrhage which did not respond to H2-receptor antagonists." | 5.27 | Long term management of hemorrhagic esophagitis with cimetidine and omeprazole. ( Bonnin, M; Hetzel, DJ, 1986) |
"Previous studies have demonstrated greater efficacy for omeprazole compared with cimetidine in patients with endoscopically verified oesophagitis, but excluded the substantial group of gastro-oesophageal reflux disease (GERD) patients with reflux symptoms but without endoscopic abnormality." | 5.08 | Omeprazole is more effective than cimetidine for the relief of all grades of gastro-oesophageal reflux disease-associated heartburn, irrespective of the presence or absence of endoscopic oesophagitis. ( Axon, AT; Bate, CM; Emmas, CE; Green, JR; Murray, FE; Taylor, MD; Tildesley, G, 1997) |
" is more effective than cimetidine 800 mg nocte in the prevention of recurrence of GERD-associated heartburn and the occurrence of underlying oesophagitis." | 5.08 | Omeprazole is more effective than cimetidine in the prevention of recurrence of GERD-associated heartburn and the occurrence of underlying oesophagitis. ( Axon, AT; Bate, CM; Emmas, C; Green, JR; Murrays, FE; Owen, SM; Taylor, MD; Tildesley, G, 1998) |
"Double-blind randomized controlled trials in single subjects (N of 1 RCTs) have demonstrated a beneficial symptomatic effect of cimetidine in reflux- or ulcer-like non-ulcer dyspepsia (NUD)." | 5.07 | Cimetidine on-demand in dyspepsia. Experience with randomized controlled single-subject trials. ( Dybdahl, J; Fosstvedt, D; Johannessen, T; Kleveland, PM; Kristensen, P; Løge, I; Petersen, H, 1992) |
"Before endoscopy a double-blind, randomized, controlled, single-subject trial comparing the symptomatic effect of 1-day treatment periods with cimetidine and placebo was conducted in patients with dyspepsia." | 5.07 | The symptomatic effect of 1-day treatment periods with cimetidine in dyspepsia. Combined results from randomized, controlled, single-subject trials. ( Dybdahl, J; Fosstvedt, D; Johannessen, T; Kleveland, PM; Kristensen, P; Løge, I; Petersen, H, 1991) |
"In a double-blind, randomized, comparative trial of the prokinetic drug cisapride and the H2-blocker cimetidine, mucosal healing and changes in symptoms of gastroesophageal reflux were evaluated in patients with erosive reflux esophagitis." | 5.06 | Double-blind comparison of cisapride and cimetidine in treatment of reflux esophagitis. ( Evreux, M; Filoche, B; Fournet, J; Fraitag, B; Galmiche, JP; Soule, JC; Vitaux, J; Zeitoun, P, 1990) |
"In a Canadian multicenter trial, a new dosing regimen of cimetidine (Tagamet)-600 mg given twice a day-was compared with the standard regimen of 300 mg four times a day in 118 evaluable patients with endoscopically proved esophagitis." | 5.05 | Cimetidine therapy for gastroesophageal reflux disease. ( Archambault, AP; Cleator, IG; Farley, A; Hershfield, NB; Navert, H; Prokipchuk, EJ; Thomson, AB, 1985) |
"To assess the effect of cimetidine and ranitidine on high density lipoprotein (HDL) cholesterol concentration two groups of eight patients with duodenal ulcer or oesophagitis matched for age, sex, and cigarette consumption were given either cimetidine 1 g daily or ranitidine 300 mg daily for one month." | 5.05 | Effects of cimetidine and ranitidine on high density lipoprotein cholesterol concentrations. ( Craig, IF; Wilson, JA, 1985) |
"The effect of the histamine H2-receptor antagonist, cimetidine, on the resistance of esophageal mucosa was investigated in an experimental model of acute esophagitis." | 3.67 | Effect of cimetidine on HCl-taurocholate-induced esophageal mucosal injury. ( Kivilaakso, E; Salo, JA, 1984) |
"The potential mucosal protective effects of a liquid sucralfate preparation and the histamine (H2)-antagonist cimetidine on acid-induced esophagitis were studied." | 3.67 | Comparison of potential cytoprotective action of sucralfate and cimetidine. Studies with experimental feline esophagitis. ( Castell, DO; Clark, S; Geisinger, KR; Katz, PO; Wu, WC, 1987) |
"We conducted a double-blind study to compare the effectiveness of oral bethanechol chloride or cimetidine in treating reflux esophagitis to evaluate the drugs' effects on the symptoms of esophagitis and its verification by endoscopy." | 3.66 | Bethanechol or cimetidine in the treatment of symptomatic reflux esophagitis: a double-blind control study. ( Chey, WY; Hamilton, D; Nadelson, N; Shak, A; Thanik, K, 1982) |
"However as esophagitis is associated with a more severe Knaus index and a greater number of gastric stress ulcer risk factors, it is suggested that decreased defense of the mucosa may be a key factor in the occurrence of this type of esophagitis." | 2.66 | [Attempt at preventive treatment of esophagitis caused by intubation during intensive care]. ( Baccino, E; Boles, JM; Cleuziou, A; Garo, B; Geier, B; Le Guillou, M; Robaszkiewicz, M, 1987) |
"In refractory cases of GERD, eosinophilic esophagitis must be considered before any surgical measure." | 1.32 | Eosinophilic infiltration of the esophagus: gastroesophageal reflux versus eosinophilic esophagitis in children--discussion on daily practice. ( Cury, EK; Faintuch, S; Schraibman, V, 2004) |
"Chest pain was associated with an episode of GER in three patients (43%)." | 1.28 | Esophageal chest pain in children with asthma. ( Berezin, S; Glassman, MS; Medow, MS; Newman, LJ, 1991) |
"Cimetidine treatment was successful for seven years but dose reduction was followed by intractable hemorrhage which did not respond to H2-receptor antagonists." | 1.27 | Long term management of hemorrhagic esophagitis with cimetidine and omeprazole. ( Bonnin, M; Hetzel, DJ, 1986) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 25 (65.79) | 18.7374 |
1990's | 11 (28.95) | 18.2507 |
2000's | 2 (5.26) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Cury, EK | 1 |
Schraibman, V | 1 |
Faintuch, S | 1 |
Hunt, RH | 1 |
Thanik, K | 1 |
Chey, WY | 1 |
Shak, A | 1 |
Hamilton, D | 1 |
Nadelson, N | 1 |
Sitges Serra, A | 1 |
Salo, JA | 1 |
Kivilaakso, E | 1 |
Audebert, M | 1 |
Huguier, M | 1 |
Cunningham, GM | 1 |
Bjark, P | 1 |
Nordgård, K | 1 |
Fahrländer, H | 1 |
Rosioru, C | 1 |
Glassman, MS | 2 |
Halata, MS | 1 |
Schwarz, SM | 1 |
Mascarenhas, MR | 1 |
McGowan, KL | 1 |
Ruchelli, E | 1 |
Athreya, B | 1 |
Altschuler, SM | 1 |
Bate, CM | 2 |
Green, JR | 2 |
Axon, AT | 2 |
Murray, FE | 1 |
Tildesley, G | 2 |
Emmas, CE | 1 |
Taylor, MD | 2 |
Murrays, FE | 1 |
Owen, SM | 1 |
Emmas, C | 1 |
Todd, JA | 1 |
Weston, T | 1 |
MacDonald, TM | 1 |
Johnston, DA | 1 |
Dillon, JF | 1 |
Pavlotzky, M | 1 |
Eschchar, I | 1 |
Neuman, M | 1 |
de Carle, DJ | 1 |
Hradsky, M | 1 |
Wikander, M | 1 |
Bardhan, KD | 2 |
Debray, C | 1 |
Favriel, JM | 1 |
Gouerou, H | 1 |
Leymarios, J | 1 |
Blum, AL | 1 |
Bucher, P | 1 |
Lepsien, G | 1 |
Weber, K | 1 |
Giger, M | 1 |
Sonnenberg, A | 1 |
Shearman, DJ | 1 |
Johannessen, T | 2 |
Petersen, H | 2 |
Kristensen, P | 2 |
Fosstvedt, D | 2 |
Kleveland, PM | 2 |
Dybdahl, J | 2 |
Løge, I | 2 |
Zeitoun, P | 2 |
Thiéfin, G | 1 |
Duchateau, A | 1 |
Diébold, MD | 1 |
Ojeda Casas, JA | 1 |
García Ara, MC | 1 |
Martín Muñoz, F | 1 |
Díaz Pena, JM | 1 |
Añibarro Bausera, B | 1 |
Escobar Castro, H | 1 |
Berezin, S | 1 |
Medow, MS | 1 |
Newman, LJ | 1 |
Galmiche, JP | 1 |
Fraitag, B | 1 |
Filoche, B | 1 |
Evreux, M | 1 |
Vitaux, J | 1 |
Fournet, J | 1 |
Soule, JC | 1 |
Morris, P | 1 |
Thompson, M | 1 |
Dhande, DS | 1 |
Hinchliffe, RF | 1 |
Jones, RB | 1 |
Daly, MJ | 1 |
Carroll, NJ | 1 |
Amair, P | 1 |
Cabrera, I | 1 |
Gonzalez, JC | 1 |
Boissiere, M | 1 |
Borowitz, SM | 1 |
Humphreys, H | 1 |
Bourke, S | 1 |
Dooley, C | 1 |
McKenna, D | 1 |
Power, B | 1 |
Keane, CT | 1 |
Sweeney, EC | 1 |
O'Moráin, C | 1 |
Hetzel, DJ | 1 |
Bonnin, M | 1 |
Baccino, E | 1 |
Boles, JM | 1 |
Le Guillou, M | 1 |
Geier, B | 1 |
Garo, B | 1 |
Robaszkiewicz, M | 1 |
Cleuziou, A | 1 |
Clark, S | 1 |
Katz, PO | 1 |
Wu, WC | 1 |
Geisinger, KR | 1 |
Castell, DO | 1 |
Archambault, AP | 1 |
Farley, A | 1 |
Cleator, IG | 1 |
Hershfield, NB | 1 |
Navert, H | 1 |
Prokipchuk, EJ | 1 |
Thomson, AB | 2 |
Wilson, JA | 1 |
Craig, IF | 1 |
Mahachai, V | 1 |
Walker, K | 1 |
Zuk, L | 1 |
Kirdeikis, P | 1 |
Fisher, D | 1 |
Brunet, K | 1 |
4 reviews available for cimetidine and Esophagitis
Article | Year |
---|---|
[Zollinger-Ellison syndrome. Experience in 14 cases and a review of the recent literature].
Topics: Adult; Cimetidine; Esophagitis; Female; Gastrins; Humans; Male; Middle Aged; Multiple Endocrine Neop | 1984 |
[Cimetidine and other H2 receptor blockers].
Topics: Burimamide; Cimetidine; Esophagitis; Esophagitis, Peptic; Gastrointestinal Hemorrhage; Guanidines; H | 1978 |
[Effects of antisecretory therapy on serum gastrin and argyrophil cells of the fundus mucosa].
Topics: Cimetidine; Duodenal Ulcer; Esophagitis; Gastric Mucosa; Gastrins; Humans; Omeprazole; Ranitidine; V | 1991 |
[Asthma and gastroesophageal reflux. Outcome of asthma after longterm medical treatment of the reflux].
Topics: Adrenal Cortex Hormones; Adrenergic beta-Antagonists; Asthma; Child; Child, Preschool; Cimetidine; E | 1990 |
12 trials available for cimetidine and Esophagitis
Article | Year |
---|---|
Cimetidine now.
Topics: Cimetidine; Clinical Trials as Topic; Esophagitis; Guanidines; Humans; Peptic Ulcer; Zollinger-Ellis | 1981 |
Omeprazole is more effective than cimetidine for the relief of all grades of gastro-oesophageal reflux disease-associated heartburn, irrespective of the presence or absence of endoscopic oesophagitis.
Topics: Adolescent; Adult; Aged; Anti-Ulcer Agents; Cimetidine; Double-Blind Method; Esophagitis; Female; Ga | 1997 |
Omeprazole is more effective than cimetidine in the prevention of recurrence of GERD-associated heartburn and the occurrence of underlying oesophagitis.
Topics: Administration, Oral; Anti-Ulcer Agents; Chi-Square Distribution; Cimetidine; Double-Blind Method; E | 1998 |
[Cimetidine: a pilot study in Falun].
Topics: Cimetidine; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Esophagitis; Guanidines; | 1979 |
Cimetidine on-demand in dyspepsia. Experience with randomized controlled single-subject trials.
Topics: Adult; Aged; Cimetidine; Confidence Intervals; Double-Blind Method; Dyspepsia; Esophagitis; Humans; | 1992 |
The symptomatic effect of 1-day treatment periods with cimetidine in dyspepsia. Combined results from randomized, controlled, single-subject trials.
Topics: Adult; Age Factors; Cimetidine; Double-Blind Method; Dyspepsia; Endoscopy, Gastrointestinal; Esophag | 1991 |
Double-blind comparison of cisapride and cimetidine in treatment of reflux esophagitis.
Topics: Adult; Cimetidine; Cisapride; Double-Blind Method; Drug Evaluation; Esophagitis; Esophagoscopy; Fema | 1990 |
Effect of treatment on Campylobacter pylori in peptic disease: a randomised prospective trial.
Topics: Adult; Campylobacter Infections; Cimetidine; Drug Therapy, Combination; Esophagitis; Female; Gastrit | 1988 |
[Attempt at preventive treatment of esophagitis caused by intubation during intensive care].
Topics: Adult; Aged; Aluminum; Aluminum Compounds; Antacids; Cimetidine; Esophagitis; Female; Humans; Inject | 1987 |
Cimetidine therapy for gastroesophageal reflux disease.
Topics: Adult; Cimetidine; Clinical Trials as Topic; Drug Administration Schedule; Esophagitis; Esophagoscop | 1985 |
Effects of cimetidine and ranitidine on high density lipoprotein cholesterol concentrations.
Topics: Cholesterol, HDL; Cimetidine; Duodenal Ulcer; Esophagitis; Female; Humans; Male; Ranitidine | 1985 |
Comparison of cimetidine and ranitidine on 24-hour intragastric acidity and serum gastrin profile in patients with esophagitis.
Topics: Adult; Aged; Cimetidine; Double-Blind Method; Eating; Esophagitis; Gastric Acid; Gastric Acidity Det | 1985 |
22 other studies available for cimetidine and Esophagitis
Article | Year |
---|---|
Eosinophilic infiltration of the esophagus: gastroesophageal reflux versus eosinophilic esophagitis in children--discussion on daily practice.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Biopsy; Child; Cimetidine; Diagnosis, Differential; Enzyme | 2004 |
Use and abuse of H2 receptor antagonists.
Topics: Cimetidine; Drug Interactions; Duodenal Ulcer; Esophagitis; Furans; Histamine H2 Antagonists; Humans | 1982 |
Bethanechol or cimetidine in the treatment of symptomatic reflux esophagitis: a double-blind control study.
Topics: Administration, Oral; Bethanechol; Bethanechol Compounds; Cimetidine; Double-Blind Method; Endoscopy | 1982 |
Effect of cimetidine on HCl-taurocholate-induced esophageal mucosal injury.
Topics: Animals; Cimetidine; Esophagitis; Hydrochloric Acid; Models, Biological; Mucous Membrane; Permeabili | 1984 |
[Can cimetidine promote the appearance of esophagitis?].
Topics: Aged; Cimetidine; Esophagitis; Female; Humans | 1984 |
Drug-induced internuclear ophthalmoplegia.
Topics: Aged; Cimetidine; Drug Interactions; Esophagitis; Female; Guanidines; Humans; Male; Middle Aged; Mit | 1983 |
[Cimetidine treatment of problem patients. Some clinical experiences in esophagitis and extensive stomach ulcers].
Topics: Aged; Cimetidine; Esophagitis; Female; Gastrectomy; Guanidines; Humans; Male; Middle Aged; Stomach U | 1982 |
[Pathophysiology, clinical aspects and therapy of gastro-esophageal reflux disease].
Topics: Antacids; Barrett Esophagus; Candidiasis; Cholic Acids; Cimetidine; Diagnosis, Differential; Endosco | 1981 |
Esophagitis and Helicobacter pylori in children: incidence and therapeutic implications.
Topics: Adolescent; Amoxicillin; Bismuth; Child; Cimetidine; Esophagitis; Female; Follow-Up Studies; Helicob | 1993 |
Acremonium infection of the esophagus.
Topics: Acremonium; Barrett Esophagus; Child, Preschool; Cimetidine; Connective Tissue Diseases; Esophageal | 1997 |
The prescribing of acid suppressants prior to the endoscopic diagnosis of Barrett's oesophagus and oesophagitis.
Topics: Antacids; Barrett Esophagus; Cimetidine; Drug Prescriptions; Endoscopy; Esophagitis; Female; Humans; | 2001 |
Rational treatment of oesophagitis.
Topics: Alginates; Antacids; Barium Sulfate; Biopsy; Cimetidine; Esophageal Stenosis; Esophagitis; Esophagos | 1978 |
Cimetidine in "chickenpox oesophagitis".
Topics: Chickenpox; Cimetidine; Esophagitis; Guanidines; Humans | 1978 |
[Esophagitis in a patient taking cimetidine].
Topics: Cimetidine; Esophagitis; Guanidines; Humans; Male; Middle Aged; Stomach Ulcer | 1978 |
[Treatment of reflux disease (author's transl)].
Topics: Alginates; Antacids; Body Weight; Cimetidine; Esophagitis; Gastroesophageal Reflux; Humans; Metoclop | 1978 |
The treatment of dyspepsia.
Topics: Antacids; Bismuth; Carbenoxolone; Cimetidine; Dyspepsia; Esophagitis; Humans; Metoclopramide; Parasy | 1977 |
Esophageal chest pain in children with asthma.
Topics: Adolescent; Antacids; Asthma; Chest Pain; Child; Cimetidine; Endoscopy, Digestive System; Esophagiti | 1991 |
Omeprazole in the treatment of erosive oesophagitis refractory to high dose cimetidine and ranitidine.
Topics: Adult; Aged; Aged, 80 and over; Cimetidine; Esophagitis; Female; Humans; Male; Middle Aged; Omeprazo | 1990 |
Relationship between upper gastrointestinal symptoms and lesions on CAPD patients.
Topics: Adult; Cimetidine; Endoscopy, Gastrointestinal; Esophagitis; Female; Gastritis; Gastrointestinal Dis | 1989 |
Ulcerative esophagitis. A rare source of upper gastrointestinal bleeding in a neonate. Use of fiberoptic endoscopy for diagnosis.
Topics: Cimetidine; Esophagitis; Esophagoscopy; Female; Fiber Optic Technology; Hematemesis; Humans; Infant, | 1989 |
Long term management of hemorrhagic esophagitis with cimetidine and omeprazole.
Topics: Anemia; Anti-Ulcer Agents; Benzimidazoles; Cimetidine; Esophagitis; Gastrointestinal Hemorrhage; Hum | 1986 |
Comparison of potential cytoprotective action of sucralfate and cimetidine. Studies with experimental feline esophagitis.
Topics: Animals; Cats; Cimetidine; Endoscopy; Epithelium; Esophagitis; Esophagus; Fiber Optic Technology; Hy | 1987 |