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cimetidine and Esophageal Stenosis

cimetidine has been researched along with Esophageal Stenosis in 14 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Esophageal Stenosis: A stricture of the ESOPHAGUS. Most are acquired but can be congenital.

Research Excerpts

ExcerptRelevanceReference
"We conclude that conservative treatment of peptic esophageal strictures yields good long-term results in 85% of patients, provided that a high dose of cimetidine is taken on a life-long basis."6.66Long-term treatment of peptic esophageal stenosis with dilatation and cimetidine: factors influencing clinical result. ( Appel, WH; Schemper, M; Schiessel, R; Starlinger, M, 1985)
"Twenty patients with reflux oesophagitis causing a tight peptic oesophageal stricture entered a randomised double-blind crossover trial in which they received cimetidine, 1."5.04Cimetidine in treatment of reflux oesophagitis with peptic stricture. ( Atkinson, M; Dronfield, MW; Ferguson, R, 1979)
"We conclude that conservative treatment of peptic esophageal strictures yields good long-term results in 85% of patients, provided that a high dose of cimetidine is taken on a life-long basis."2.66Long-term treatment of peptic esophageal stenosis with dilatation and cimetidine: factors influencing clinical result. ( Appel, WH; Schemper, M; Schiessel, R; Starlinger, M, 1985)
"Peptic esophageal strictures are a common sequelae of long-standing reflux esophagitis."2.38Peptic strictures of the esophagus. ( Marks, RD; Richter, JE, 1993)
"Between 1965 and 1990 200 patients were treated for peptic esophageal stricture by surgery or bougienage with antisecretory medication."1.29Peptic esophageal stricture: is surgery still necessary? ( Bischof, G; Feil, W; Riegler, M; Schiessel, R; Wenzl, E, 1996)
"Cimetidine therapy was not effective in preventing restricture of the esophagus."1.26Barrett's ulcer and treatment with cimetidine. ( Kalra, TM; Kothari, T; Mangla, JC, 1980)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-199010 (71.43)18.7374
1990's4 (28.57)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Noya, G1
Dettori, G1
Muscas, AG1
Delogu, L1
Niolu, P1
Marongiu, G1
Spirito, R1
Biglioli, P1
Bendig, DW1
Seilheimer, DK1
Wagner, ML1
Ferry, GD1
Barrison, GM1
Saltzman, M1
Barwick, K1
McCallum, RW1
Siewert, R1
Lepsien, G1
Schattenmann, G1
Weiser, HF1
Kothari, T1
Mangla, JC1
Kalra, TM1
Jönsson, P1
Högström, H1
Marks, RD1
Richter, JE1
Bischof, G1
Feil, W1
Riegler, M1
Wenzl, E1
Schiessel, R3
Mascarenhas, MR1
McGowan, KL1
Ruchelli, E1
Athreya, B1
Altschuler, SM1
de Carle, DJ1
Ferguson, R1
Dronfield, MW1
Atkinson, M1
Starlinger, M2
Appel, WH2
Schemper, M2
Leahy, AL1
Gorey, TF1
McMullin, JP1

Reviews

1 review available for cimetidine and Esophageal Stenosis

ArticleYear
Peptic strictures of the esophagus.
    The American journal of gastroenterology, 1993, Volume: 88, Issue:8

    Topics: Behavior Therapy; Causality; Cimetidine; Diagnosis, Differential; Dilatation; Esophageal Stenosis; E

1993

Trials

2 trials available for cimetidine and Esophageal Stenosis

ArticleYear
Cimetidine in treatment of reflux oesophagitis with peptic stricture.
    British medical journal, 1979, Aug-25, Volume: 2, Issue:6188

    Topics: Aged; Cimetidine; Clinical Trials as Topic; Dilatation; Double-Blind Method; Esophageal Stenosis; Es

1979
Long-term treatment of peptic esophageal stenosis with dilatation and cimetidine: factors influencing clinical result.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1985, Volume: 17, Issue:4

    Topics: Adult; Aged; Cimetidine; Clinical Trials as Topic; Combined Modality Therapy; Dilatation; Esophageal

1985

Other Studies

11 other studies available for cimetidine and Esophageal Stenosis

ArticleYear
[Cimetidine in the treatment of peptic esophagitis. Clinical findings and results with 171 patients].
    Minerva medica, 1983, Apr-07, Volume: 74, Issue:14-15

    Topics: Adolescent; Adult; Aged; Cimetidine; Drug Evaluation; Esophageal Stenosis; Esophagitis, Peptic; Fema

1983
Complications of gastroesophageal reflux in patients with cystic fibrosis.
    The Journal of pediatrics, 1982, Volume: 100, Issue:4

    Topics: Adolescent; Adult; Antacids; Child; Cimetidine; Cystic Fibrosis; Esophageal Stenosis; Esophagitis, P

1982
Progression of cimetidine-treated reflux esophagitis to a Barrett's stricture.
    Digestive diseases and sciences, 1982, Volume: 27, Issue:2

    Topics: Aged; Barrett Esophagus; Cimetidine; Esophageal Diseases; Esophageal Stenosis; Esophagitis, Peptic;

1982
[Therapeutic results of peptic stenosis in the esophagus (author's transl)].
    Langenbecks Archiv fur Chirurgie, 1980, Volume: 353, Issue:3

    Topics: Adult; Aged; Antacids; Cimetidine; Dilatation; Esophageal Stenosis; Esophagitis, Peptic; Esophagopla

1980
Barrett's ulcer and treatment with cimetidine.
    Archives of internal medicine, 1980, Volume: 140, Issue:4

    Topics: Aged; Cimetidine; Esophageal Diseases; Esophageal Stenosis; Female; Guanidines; Humans; Male; Middle

1980
Non-operative treatment of benign oesophageal strictures: results after endoscopic balloon dilatation and H2-antagonists.
    The European journal of surgery = Acta chirurgica, 1993, Volume: 159, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Catheterization; Cimetidine; Combined Modality Therapy; Esophageal S

1993
Peptic esophageal stricture: is surgery still necessary?
    Wiener klinische Wochenschrift, 1996, Volume: 108, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Cimetidine; Combined Modality Therapy

1996
Acremonium infection of the esophagus.
    Journal of pediatric gastroenterology and nutrition, 1997, Volume: 24, Issue:3

    Topics: Acremonium; Barrett Esophagus; Child, Preschool; Cimetidine; Connective Tissue Diseases; Esophageal

1997
Rational treatment of oesophagitis.
    Drugs, 1978, Volume: 15, Issue:3

    Topics: Alginates; Antacids; Barium Sulfate; Biopsy; Cimetidine; Esophageal Stenosis; Esophagitis; Esophagos

1978
[Conservative treatment of peptic esophageal stenoses. Results of a prospective long-term study].
    Wiener klinische Wochenschrift, 1986, May-30, Volume: 98, Issue:11

    Topics: Cimetidine; Combined Modality Therapy; Dilatation; Esophageal Stenosis; Esophagitis, Peptic; Esophag

1986
Serial dilatation of peptic strictures of the oesophagus: a planned approach.
    Irish journal of medical science, 1986, Volume: 155, Issue:11

    Topics: Adult; Aged; Alginates; Aluminum Hydroxide; Bicarbonates; Cimetidine; Dilatation; Drug Combinations;

1986