cimetidine has been researched along with Erythrohepatic Protoporphyria in 4 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cimetidine might inhibit δ-aminolevulinic acid synthase influencing the heme biosynthesis." | 2.82 | Cimetidine for erythropoietic protoporphyria. ( Heerfordt, IM; Lerche, CM; Wulf, HC, 2022) |
| "A treatment with cimetidine appears to be an excellent therapeutic option in children with Erythropoietic protoporphyria." | 1.91 | Erythropoietic protoporphyria: case reports for clinical and therapeutic hints. ( Berti, I; Burlo, F; De Martino, E; Marchini, S; Pastore, S; Severini, GM; Tommasini, A; Tumminelli, C; Zanon, D, 2023) |
| "Cimetidine has been shown to inhibit heme biosynthesis and results in symptomatic improvement in patients with acute intermittent porphyria (AIP) and porphyria cutanea tarda (PCT)." | 1.43 | Novel Treatment Using Cimetidine for Erythropoietic Protoporphyria in Children. ( Sheu, SL; Teng, JM; Tu, JH, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Heerfordt, IM | 1 |
| Lerche, CM | 1 |
| Wulf, HC | 1 |
| Tumminelli, C | 1 |
| Burlo, F | 1 |
| Pastore, S | 1 |
| Severini, GM | 1 |
| Berti, I | 1 |
| Marchini, S | 1 |
| Zanon, D | 1 |
| De Martino, E | 1 |
| Tommasini, A | 1 |
| Fujimori, N | 1 |
| Komatsu, M | 1 |
| Tanaka, N | 1 |
| Iwaya, M | 1 |
| Nakano, H | 1 |
| Sugiura, A | 1 |
| Yamazaki, T | 1 |
| Shibata, S | 1 |
| Iwaya, Y | 1 |
| Muraki, T | 1 |
| Ichikawa, Y | 1 |
| Kimura, T | 1 |
| Joshita, S | 1 |
| Umemura, T | 1 |
| Matsumoto, A | 1 |
| Tanaka, E | 1 |
| Tu, JH | 1 |
| Sheu, SL | 1 |
| Teng, JM | 1 |
1 review available for cimetidine and Erythrohepatic Protoporphyria
| Article | Year |
|---|---|
Cimetidine for erythropoietic protoporphyria.
Topics: Cimetidine; Ferrochelatase; Heme; Humans; Photochemotherapy; Photosensitivity Disorders; Protoporphy | 2022 |
3 other studies available for cimetidine and Erythrohepatic Protoporphyria
| Article | Year |
|---|---|
Erythropoietic protoporphyria: case reports for clinical and therapeutic hints.
Topics: Child; Child, Preschool; Cimetidine; Delayed Diagnosis; Ferrochelatase; Humans; Photosensitivity Dis | 2023 |
Cimetidine/lactulose therapy ameliorates erythropoietic protoporphyria-related liver injury.
Topics: 5-Aminolevulinate Synthetase; Cimetidine; Gastrointestinal Agents; Humans; Lactulose; Liver; Liver C | 2017 |
Novel Treatment Using Cimetidine for Erythropoietic Protoporphyria in Children.
Topics: Administration, Oral; Adolescent; Child; Child, Preschool; Cimetidine; Dermatologic Agents; Female; | 2016 |