Page last updated: 2024-10-25

cimetidine and Erythrohepatic Protoporphyria

cimetidine has been researched along with Erythrohepatic Protoporphyria in 4 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Research Excerpts

ExcerptRelevanceReference
"Cimetidine might inhibit δ-aminolevulinic acid synthase influencing the heme biosynthesis."2.82Cimetidine for erythropoietic protoporphyria. ( Heerfordt, IM; Lerche, CM; Wulf, HC, 2022)
"A treatment with cimetidine appears to be an excellent therapeutic option in children with Erythropoietic protoporphyria."1.91Erythropoietic protoporphyria: case reports for clinical and therapeutic hints. ( Berti, I; Burlo, F; De Martino, E; Marchini, S; Pastore, S; Severini, GM; Tommasini, A; Tumminelli, C; Zanon, D, 2023)
"Cimetidine has been shown to inhibit heme biosynthesis and results in symptomatic improvement in patients with acute intermittent porphyria (AIP) and porphyria cutanea tarda (PCT)."1.43Novel Treatment Using Cimetidine for Erythropoietic Protoporphyria in Children. ( Sheu, SL; Teng, JM; Tu, JH, 2016)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Heerfordt, IM1
Lerche, CM1
Wulf, HC1
Tumminelli, C1
Burlo, F1
Pastore, S1
Severini, GM1
Berti, I1
Marchini, S1
Zanon, D1
De Martino, E1
Tommasini, A1
Fujimori, N1
Komatsu, M1
Tanaka, N1
Iwaya, M1
Nakano, H1
Sugiura, A1
Yamazaki, T1
Shibata, S1
Iwaya, Y1
Muraki, T1
Ichikawa, Y1
Kimura, T1
Joshita, S1
Umemura, T1
Matsumoto, A1
Tanaka, E1
Tu, JH1
Sheu, SL1
Teng, JM1

Reviews

1 review available for cimetidine and Erythrohepatic Protoporphyria

ArticleYear
Cimetidine for erythropoietic protoporphyria.
    Photodiagnosis and photodynamic therapy, 2022, Volume: 38

    Topics: Cimetidine; Ferrochelatase; Heme; Humans; Photochemotherapy; Photosensitivity Disorders; Protoporphy

2022

Other Studies

3 other studies available for cimetidine and Erythrohepatic Protoporphyria

ArticleYear
Erythropoietic protoporphyria: case reports for clinical and therapeutic hints.
    Italian journal of pediatrics, 2023, Nov-23, Volume: 49, Issue:1

    Topics: Child; Child, Preschool; Cimetidine; Delayed Diagnosis; Ferrochelatase; Humans; Photosensitivity Dis

2023
Cimetidine/lactulose therapy ameliorates erythropoietic protoporphyria-related liver injury.
    Clinical journal of gastroenterology, 2017, Volume: 10, Issue:5

    Topics: 5-Aminolevulinate Synthetase; Cimetidine; Gastrointestinal Agents; Humans; Lactulose; Liver; Liver C

2017
Novel Treatment Using Cimetidine for Erythropoietic Protoporphyria in Children.
    JAMA dermatology, 2016, 11-01, Volume: 152, Issue:11

    Topics: Administration, Oral; Adolescent; Child; Child, Preschool; Cimetidine; Dermatologic Agents; Female;

2016