cimetidine has been researched along with Erythema in 12 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Erythema: Redness of the skin produced by congestion of the capillaries. This condition may result from a variety of disease processes.
| Excerpt | Relevance | Reference |
|---|---|---|
| " 2 Simultaneous systemic administration of cimetidine and chlorpheniramine (an H1-receptor antagonist) was more effective than either drug alone in inhibition of the erythematous reaction both to exogenous histamine, and endogenous histamine secreted by skin mast cells in response to compound 48/80." | 5.04 | Vascular reactions to histamine and compound 48/80 in human skin: suppression by a histamine H2-receptor blocking agent. ( Greaves, MW; Marks, R, 1977) |
| "Antihistamine treatment significantly reduced the increase in plasma histamine levels after the first histamine injection but did not alter the levels after subsequent histamine injections." | 2.68 | Administration of H1 and H2 antagonists for chemoprophylaxis: a double-blind, placebo-controlled study in healthy volunteers. ( Doenicke, A; Hoernecke, R; Lorenz, W; Moss, J; Ostwald, P; Toledano, A, 1997) |
| "Cimetidine was without influence on these parameters and the effects of the combined therapy of chlorpheniramine and cimetidine were not significantly different from those due to chlorpheniramine alone." | 2.67 | Effects of selective histamine receptor antagonists on skin responses to intradermal bradykinin in healthy volunteers. ( Cooke, ED; Li Kam Wa, TC; Turner, P, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (50.00) | 18.7374 |
| 1990's | 5 (41.67) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Thomas, RR | 1 |
| Quinn, MG | 1 |
| Schuler, B | 1 |
| Grem, JL | 1 |
| Tan, OT | 1 |
| Stafford, TJ | 1 |
| Sarkany, I | 1 |
| Gaylarde, PM | 1 |
| Tilsey, C | 1 |
| Payne, JP | 1 |
| Argenbright, LW | 1 |
| Forbes, PD | 1 |
| Stewart, GJ | 1 |
| Inoue, A | 1 |
| Teramae, H | 1 |
| Hisa, T | 1 |
| Taniguchi, S | 1 |
| Chanoki, M | 1 |
| Hamada, T | 1 |
| Doenicke, A | 1 |
| Moss, J | 1 |
| Toledano, A | 1 |
| Hoernecke, R | 1 |
| Lorenz, W | 1 |
| Ostwald, P | 1 |
| Helmbold, P | 1 |
| Hegemann, B | 1 |
| Dickert, C | 1 |
| Marsch, WC | 1 |
| Avella, J | 1 |
| Madsen, JE | 1 |
| Binder, HJ | 1 |
| Askenase, PW | 1 |
| Greaves, M | 1 |
| Marks, R | 2 |
| Robertson, I | 1 |
| Greaves, MW | 1 |
| Li Kam Wa, TC | 1 |
| Cooke, ED | 1 |
| Turner, P | 1 |
| Pentland, AP | 1 |
| Mahoney, M | 1 |
| Jacobs, SC | 1 |
| Holtzman, MJ | 1 |
| Ikai, K | 1 |
| Danno, K | 1 |
| Horio, T | 1 |
| Narumiya, S | 1 |
2 reviews available for cimetidine and Erythema
| Article | Year |
|---|---|
Hypersensitivity and idiosyncratic reactions to oxaliplatin.
Topics: Administration, Oral; Adult; Aged; Anti-Inflammatory Agents; Antiemetics; Antineoplastic Agents; Cim | 2003 |
Receptors for histamine in human skin blood vessels: a review.
Topics: Chlorpheniramine; Cimetidine; Erythema; Humans; Receptors, Histamine; Skin | 1977 |
4 trials available for cimetidine and Erythema
| Article | Year |
|---|---|
Administration of H1 and H2 antagonists for chemoprophylaxis: a double-blind, placebo-controlled study in healthy volunteers.
Topics: Adult; Blood Pressure; Cimetidine; Dimethindene; Double-Blind Method; Erythema; Female; Headache; He | 1997 |
Effect of histamine H2-receptor antagonists on delayed hypersensitivity.
Topics: Cimetidine; Drug Hypersensitivity; Duodenal Ulcer; Erythema; Female; Guanidines; Humans; Hypersensit | 1978 |
Vascular reactions to histamine and compound 48/80 in human skin: suppression by a histamine H2-receptor blocking agent.
Topics: Adult; Chlorpheniramine; Cimetidine; Double-Blind Method; Drug Interactions; Erythema; Female; Guani | 1977 |
Effects of selective histamine receptor antagonists on skin responses to intradermal bradykinin in healthy volunteers.
Topics: Adult; Blood Circulation; Bradykinin; Capsules; Chlorpheniramine; Cimetidine; Double-Blind Method; E | 1992 |
6 other studies available for cimetidine and Erythema
| Article | Year |
|---|---|
Suppression of alcohol-induced flushing by a combination of H1 and H2 histamine antagonists.
Topics: Adult; Alcoholic Beverages; Chlorpheniramine; Cimetidine; Drug Therapy, Combination; Erythema; Ethan | 1982 |
Quantitation of phototoxic hyperemia and permeability to protein. I. Inhibition by histamine (H1 and H2) and serotonin receptor antagonists in pig skin.
Topics: Animals; Anthracenes; Capillary Permeability; Cimetidine; Erythema; Female; Histamine Antagonists; M | 1980 |
Fixed drug eruption due to cimetidine.
Topics: Cimetidine; Drug Eruptions; Erythema; Female; Hand Dermatoses; Humans; Middle Aged; Pruritus | 1995 |
Symmetric ptychotropic and nonpigmenting fixed drug eruption due to cimetidine (so-called baboon syndrome)
Topics: Aged; Anal Canal; Analgesics, Non-Narcotic; Cimetidine; Drug Eruptions; Erythema; Genitalia, Male; H | 1998 |
Enhanced prostaglandin synthesis after ultraviolet injury is mediated by endogenous histamine stimulation. A mechanism for irradiation erythema.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Brompheniramine; Cells, Cultured; Chromatography, High | 1990 |
Ear swelling in response to UVB irradiation.
Topics: Animals; Betamethasone; Cimetidine; Diphenhydramine; Ear, External; Edema; Erythema; Indomethacin; M | 1986 |