Page last updated: 2024-10-25

cimetidine and Dyspepsia

cimetidine has been researched along with Dyspepsia in 58 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Dyspepsia: Impaired digestion, especially after eating.

Research Excerpts

ExcerptRelevanceReference
"To compare ecabet sodium and cimetidine in relieving symptoms of functional dyspepsia."9.12Efficacy and safety of ecabet sodium on functional dyspepsia: a prospective, double-blinded, randomized, multi-center controlled trial. ( Choi, SR; Hahm, KB; Kim, JJ; Kim, N; Kim, SK; Lee, DH; Lee, EH; Lee, JH; Lee, ST; Park, JJ; Rhee, JC, 2006)
"Double-blind randomized controlled trials in single subjects (N of 1 RCTs) have demonstrated a beneficial symptomatic effect of cimetidine in reflux- or ulcer-like non-ulcer dyspepsia (NUD)."9.07Cimetidine on-demand in dyspepsia. Experience with randomized controlled single-subject trials. ( Dybdahl, J; Fosstvedt, D; Johannessen, T; Kleveland, PM; Kristensen, P; Løge, I; Petersen, H, 1992)
"Before endoscopy a double-blind, randomized, controlled, single-subject trial comparing the symptomatic effect of 1-day treatment periods with cimetidine and placebo was conducted in patients with dyspepsia."9.07The symptomatic effect of 1-day treatment periods with cimetidine in dyspepsia. Combined results from randomized, controlled, single-subject trials. ( Dybdahl, J; Fosstvedt, D; Johannessen, T; Kleveland, PM; Kristensen, P; Løge, I; Petersen, H, 1991)
"A randomized double-blind antacid-controlled study was carried out to investigate the speed of onset of relief from dyspeptic pain with a novel, chewable formulation of cimetidine in 80 patients with persistent dyspepsia."9.06Chewable cimetidine versus chewable antacid in dyspepsia: which provides faster pain relief? ( Parr, SN, 1989)
"The effect of cimetidine and placebo was examined in 123 patients with non-ulcer dyspepsia (NUD) by means of a 12-day multi-crossover model with 5 regular interchanges between cimetidine and placebo."9.06Cimetidine responders in non-ulcer dyspepsia. ( Fjøsne, U; Hafstad, PE; Halvorsen, T; Johannessen, T; Kleveland, PM; Kristensen, P; Løge, I; Petersen, H; Sandbakken, P, 1988)
"A randomized double-blind, placebo-controlled study was carried out in 56 patients with essential dyspepsia to investigate the therapeutic efficacy of cimetidine in providing symptomatic relief."9.06Cimetidine in the treatment of non-ulcer dyspepsia: results of a randomized double-blind, placebo-controlled study. ( Broor, SL; Kumar, A; Singal, AK, 1989)
"Patients with dyspepsia of unknown origin were randomly allocated to a controlled double-blind study to examine the symptomatic effect of cimetidine and antacid especially on the relief of pain, nausea, and bloating."9.06Treatment with cimetidine, antacid, or placebo in patients with dyspepsia of unknown origin. ( Bodemar, G; Brodin, U; Gotthard, R; Jönsson, KA, 1988)
"Sixty patients with nonulcer dyspepsia took cimetidine 1 g daily or a placebo for 5 weeks in a double-blind trial."9.06A controlled trial of cimetidine for the treatment of nonulcer dyspepsia. ( Lance, P; Schiller, KF; Wastell, C, 1986)
"We randomly assigned 159 patients with non-ulcer dyspepsia, defined as chronic or recurrent epigastric pain without concomitant symptoms of the irritable bowel syndrome and with no evidence of organic disease, to treatment for three weeks with an antacid suspension one and three hours after meals, 400 mg of cimetidine twice a day, or placebo, according to a double-blind, double-dummy model."9.06Absence of therapeutic benefit from antacids or cimetidine in non-ulcer dyspepsia. ( Adami, HO; Bates, S; Bergström, R; Gustavsson, S; Lööf, L; Nyberg, A; Nyrén, O, 1986)
"A double-blind, placebo-controlled trial was performed, using 400-mg cimetidine tablets or placebo twice daily for 4 weeks in 100 patients with non-ulcer dyspepsia (NUD) and erosive prepyloric changes (EPC) grade 2 or 3."9.05Effect of cimetidine in patients with non-ulcer dyspepsia and erosive prepyloric changes. ( Berstad, A; Nesland, AA, 1985)
"The symptomatic effect of cimetidine was examined in 27 patients with non-ulcer dyspepsia (NUD) by means of a multi-cross-over model (MCO model) for testing the symptomatic effect of drugs in individual patients."9.05The effect of cimetidine in non-ulcer dyspepsia. Experience with a multi-cross-over model. ( Fjøsne, U; Hafstad, PE; Johannessen, T; Kleveland, PM; Kristensen, P; Larsen, S; Løge, I; Petersen, H; Sandbakken, P; Sandvik, L, 1985)
"The effect of cimetidine (1 g daily) and placebo was studied in a controlled clinical trial comprising 50 patients with non-ulcer dyspepsia in whom an organic abnormality responsible for the dyspeptic symptoms was not disclosed by a standardized and extensive examination programme."9.05Controlled clinical trial of treatment with cimetidine for non-ulcer dyspepsia. ( Bonnevie, O; Eriksen, J; Kelbaek, H; Linde, J; Moesgaard, F; Mungaard, S, 1985)
"Fifty patients with active peptic ulcers on endoscopy were randomly allocated for treatment with placebo or cimetidine (1."9.05The relationship between active peptic ulcer, endoscopic duodenitis and symptomatic state after treatment with cimetidine. ( Danielsson, A; Ek, B; Nyhlin, H; Steen, L, 1980)
"Functional dyspepsia is a major diagnostic and therapeutic challenge for the clinician."6.67Cisapride or cimetidine in the treatment of functional dyspepsia. Results of a double-blind, randomized, Swiss multicentre study. ( Brignoli, R; Halter, F; Miazza, B, 1994)
"Pirenzepine was not superior to placebo in decreasing symptoms."6.66Randomized, double-blind, placebo-controlled crossover trial of cimetidine and pirenzepine in nonulcer dyspepsia. ( Hayden, A; McNeil, D; Piper, DW; Talley, NJ, 1986)
"To compare ecabet sodium and cimetidine in relieving symptoms of functional dyspepsia."5.12Efficacy and safety of ecabet sodium on functional dyspepsia: a prospective, double-blinded, randomized, multi-center controlled trial. ( Choi, SR; Hahm, KB; Kim, JJ; Kim, N; Kim, SK; Lee, DH; Lee, EH; Lee, JH; Lee, ST; Park, JJ; Rhee, JC, 2006)
" Ulcer-like dyspepsia seemed to benefit from omeprazole."5.09A randomised controlled trial of four management strategies for dyspepsia: relationships between symptom subgroups and strategy outcome. ( Buskens, E; de Wit, NJ; Lewin van den Broek, NT; Numans, ME; Smout, AJ; Verheij, TJ, 2001)
"Before endoscopy a double-blind, randomized, controlled, single-subject trial comparing the symptomatic effect of 1-day treatment periods with cimetidine and placebo was conducted in patients with dyspepsia."5.07The symptomatic effect of 1-day treatment periods with cimetidine in dyspepsia. Combined results from randomized, controlled, single-subject trials. ( Dybdahl, J; Fosstvedt, D; Johannessen, T; Kleveland, PM; Kristensen, P; Løge, I; Petersen, H, 1991)
"Double-blind randomized controlled trials in single subjects (N of 1 RCTs) have demonstrated a beneficial symptomatic effect of cimetidine in reflux- or ulcer-like non-ulcer dyspepsia (NUD)."5.07Cimetidine on-demand in dyspepsia. Experience with randomized controlled single-subject trials. ( Dybdahl, J; Fosstvedt, D; Johannessen, T; Kleveland, PM; Kristensen, P; Løge, I; Petersen, H, 1992)
"A randomized double-blind antacid-controlled study was carried out to investigate the speed of onset of relief from dyspeptic pain with a novel, chewable formulation of cimetidine in 80 patients with persistent dyspepsia."5.06Chewable cimetidine versus chewable antacid in dyspepsia: which provides faster pain relief? ( Parr, SN, 1989)
"The effect of cimetidine and placebo was examined in 123 patients with non-ulcer dyspepsia (NUD) by means of a 12-day multi-crossover model with 5 regular interchanges between cimetidine and placebo."5.06Cimetidine responders in non-ulcer dyspepsia. ( Fjøsne, U; Hafstad, PE; Halvorsen, T; Johannessen, T; Kleveland, PM; Kristensen, P; Løge, I; Petersen, H; Sandbakken, P, 1988)
"A randomized double-blind, placebo-controlled study was carried out in 56 patients with essential dyspepsia to investigate the therapeutic efficacy of cimetidine in providing symptomatic relief."5.06Cimetidine in the treatment of non-ulcer dyspepsia: results of a randomized double-blind, placebo-controlled study. ( Broor, SL; Kumar, A; Singal, AK, 1989)
"We randomly assigned 159 patients with non-ulcer dyspepsia, defined as chronic or recurrent epigastric pain without concomitant symptoms of the irritable bowel syndrome and with no evidence of organic disease, to treatment for three weeks with an antacid suspension one and three hours after meals, 400 mg of cimetidine twice a day, or placebo, according to a double-blind, double-dummy model."5.06Absence of therapeutic benefit from antacids or cimetidine in non-ulcer dyspepsia. ( Adami, HO; Bates, S; Bergström, R; Gustavsson, S; Lööf, L; Nyberg, A; Nyrén, O, 1986)
"Sixty patients with nonulcer dyspepsia took cimetidine 1 g daily or a placebo for 5 weeks in a double-blind trial."5.06A controlled trial of cimetidine for the treatment of nonulcer dyspepsia. ( Lance, P; Schiller, KF; Wastell, C, 1986)
"Patients with dyspepsia of unknown origin were randomly allocated to a controlled double-blind study to examine the symptomatic effect of cimetidine and antacid especially on the relief of pain, nausea, and bloating."5.06Treatment with cimetidine, antacid, or placebo in patients with dyspepsia of unknown origin. ( Bodemar, G; Brodin, U; Gotthard, R; Jönsson, KA, 1988)
"Fifty patients with active peptic ulcers on endoscopy were randomly allocated for treatment with placebo or cimetidine (1."5.05The relationship between active peptic ulcer, endoscopic duodenitis and symptomatic state after treatment with cimetidine. ( Danielsson, A; Ek, B; Nyhlin, H; Steen, L, 1980)
"The symptomatic effect of cimetidine was examined in 27 patients with non-ulcer dyspepsia (NUD) by means of a multi-cross-over model (MCO model) for testing the symptomatic effect of drugs in individual patients."5.05The effect of cimetidine in non-ulcer dyspepsia. Experience with a multi-cross-over model. ( Fjøsne, U; Hafstad, PE; Johannessen, T; Kleveland, PM; Kristensen, P; Larsen, S; Løge, I; Petersen, H; Sandbakken, P; Sandvik, L, 1985)
"The effect of cimetidine (1 g daily) and placebo was studied in a controlled clinical trial comprising 50 patients with non-ulcer dyspepsia in whom an organic abnormality responsible for the dyspeptic symptoms was not disclosed by a standardized and extensive examination programme."5.05Controlled clinical trial of treatment with cimetidine for non-ulcer dyspepsia. ( Bonnevie, O; Eriksen, J; Kelbaek, H; Linde, J; Moesgaard, F; Mungaard, S, 1985)
"A double-blind, placebo-controlled trial was performed, using 400-mg cimetidine tablets or placebo twice daily for 4 weeks in 100 patients with non-ulcer dyspepsia (NUD) and erosive prepyloric changes (EPC) grade 2 or 3."5.05Effect of cimetidine in patients with non-ulcer dyspepsia and erosive prepyloric changes. ( Berstad, A; Nesland, AA, 1985)
"Based on these data both treatments are significantly more effective than placebo in the symptomatic treatment of non-ulcer dyspepsia, with gastroprokinetics (cisapride, domperidone) being more effective than histamine H2-receptor antagonists (cimetidine, ranitidine)."4.81Treatment of non-ulcer dyspepsia: a meta-analysis of placebo-controlled prospective studies. ( Allescher, HD; Böckenhoff, A; Hartung, J; Knapp, G; Wienbeck, M, 2001)
"A theoretical investigation was carried out to determine whether the use of an antibody test for Helicobacter pylori (HP) and the use of bismuth oxide with optional antibiotics, would be cost effective in the diagnosis and treatment of patients with dyspepsia."3.68[Costs and effectiveness of diagnosis and treatment of patients with dyspepsia, determined with the aid of a computer model]. ( Loffeld, RJ; Rutten, FF; Schipper, CK, 1993)
" The advantages of the single case approach and the impact of the MCOM is illustrated by the results from a study of the effect of cimetidine in non ulcer dyspepsia."3.67Experience with a multi crossover model in dyspepsia. ( Fosstvedt, D; Johannessen, T; Petersen, H, 1988)
" pylori eradication (which was possible in 84% of the patients), at the end of the 1-year study period, on an intention to treat basis 62% of the patients could either stop or significantly reduce dosage of their H2RA."2.70Helicobacter pylori eradication in patients on long-term H2 receptor antagonists. Economic and symptomatic benefits. A large prospective study in primary care. ( Giaffer, MH; Verma, S, 2002)
"Functional dyspepsia is a major diagnostic and therapeutic challenge for the clinician."2.67Cisapride or cimetidine in the treatment of functional dyspepsia. Results of a double-blind, randomized, Swiss multicentre study. ( Brignoli, R; Halter, F; Miazza, B, 1994)
"Pirenzepine was not superior to placebo in decreasing symptoms."2.66Randomized, double-blind, placebo-controlled crossover trial of cimetidine and pirenzepine in nonulcer dyspepsia. ( Hayden, A; McNeil, D; Piper, DW; Talley, NJ, 1986)
"Cimetidine treatment resulted in a significant increase in plasma testosterone levels which was not found in the ranitidine group."2.66A comparative study of the effects of ranitidine and cimetidine on carbohydrate tolerance, growth hormone secretion and the hypothalamic-pituitary-gonadal axis in man. ( Amphlett, G; Barnes, GD; Hoad, J; Lowry, C; Riley, AJ; Saunders, J; Scobie, IN; Sonksen, PH; Wheeler, MJ, 1986)
"Acute hypocalcemia is generally caused by a sudden drop in serum calcium ion and presents with a mild or severe form of tetany."1.91Hypocalcemic tetany associated with simultaneous administration of cimetidine and nifedipine: a case report. ( Bezabhe, WM; Bezabih, YM; Bimrew, MA, 2023)
" To examine the potential for drug-drug interactions at these two transporters, the pharmacokinetics of gabapentin enacarbil were evaluated in healthy adults after administration alone or in combination with either naproxen (an MCT-1 substrate) or cimetidine (an OCT2 substrate)."1.36Clinical pharmacokinetic drug interaction studies of gabapentin enacarbil, a novel transported prodrug of gabapentin, with naproxen and cimetidine. ( Blumenthal, R; Cundy, KC; Ho, J; Lal, R; Luo, W; Sukbuntherng, J; Vicente, V, 2010)
"Cimetidine was found to have no effect on the histological features of chronic/acute inflammation and erosion."1.27Histological findings in erosive prepyloric changes. ( Berstad, A; Nesland, AA; Serck-Hanssen, A, 1986)

Research

Studies (58)

TimeframeStudies, this research(%)All Research%
pre-199040 (68.97)18.7374
1990's10 (17.24)18.2507
2000's6 (10.34)29.6817
2010's1 (1.72)24.3611
2020's1 (1.72)2.80

Authors

AuthorsStudies
Bezabih, YM1
Bimrew, MA1
Bezabhe, WM1
Lal, R1
Sukbuntherng, J1
Luo, W1
Vicente, V1
Blumenthal, R1
Ho, J1
Cundy, KC1
Lee, JH2
Kim, JJ1
Hahm, KB1
Lee, DH1
Kim, N1
Kim, SK1
Park, JJ1
Choi, SR1
Lee, ST1
Lee, EH1
Rhee, JC1
Sakamoto, C1
Ogoshi, K1
Saigenji, K1
Narisawa, R1
Nagura, H1
Mine, T1
Tada, M1
Umegaki, E1
Maekawa, T1
Maekawa, R1
Maeda, K1
Reed, PI1
Smith, PL1
Haines, K1
House, FR1
Walters, CL1
Gray, GR2
McWhinnie, D1
Smith, IS2
Gillespie, G2
Schiller, KF2
Bendtsen, F2
Danø, P2
Guldhammer, B2
Remvig, L2
Krogsøe, O1
Kang, JY1
Ng, SK1
Guan, R1
Kaye, WA1
Passero, MA1
Solomon, RJ1
Johnson, LA1
Thomson, AB1
Brust, R1
Dwyer, JM1
Wensel, R1
Sherbaniuk, R1
Walker, K1
Barbezat, GO1
Marks, IN1
Wright, JP1
Denyer, M1
Garisch, JA1
Lucke, W1
Danielsson, A1
Ek, B1
Nyhlin, H1
Steen, L1
Halter, F1
Miazza, B1
Brignoli, R1
Saha, N1
Sachdev, A1
Bhasin, DK1
Sankaranahyanan, A1
Khosla, PP1
Singh, K1
Sharma, PL1
Schipper, CK1
Rutten, FF1
Loffeld, RJ1
Trimble, I1
Derrett, C1
Lamers, CB1
Lewin van den Broek, NT1
Numans, ME1
Buskens, E1
Verheij, TJ1
de Wit, NJ1
Smout, AJ1
Allescher, HD1
Böckenhoff, A1
Knapp, G1
Wienbeck, M1
Hartung, J1
Redstone, HA1
Barrowman, N1
Veldhuyzen Van Zanten, SJ1
Verma, S1
Giaffer, MH1
Mullen, PW1
Mackenzie, I1
Campa, PP1
Tomassini, T1
De Curtis, G1
Attili, AF1
Shearman, DJ1
Johannessen, T8
Petersen, H7
Kristensen, P7
Fosstvedt, D3
Kleveland, PM7
Dybdahl, J2
Løge, I7
Singh, S1
Singh, N1
Kochhar, R1
Talwar, P1
Mehta, SK1
Jensen, SL1
Funch Jensen, P1
Singal, AK1
Kumar, A1
Broor, SL1
Jönsson, KA2
Gotthard, R2
Bodemar, G2
Brodin, U2
Parr, SN1
Hernandez Avila, M1
Walker, AM1
Romieu, I1
Spiegelman, DL1
Perera, DR1
Jick, H1
Rokkas, T1
Sladen, GE1
Zuberi, SJ1
Qureshi, H1
Banatwala, NS1
Rehman, R1
Alam, E1
Fjøsne, U5
Halvorsen, T2
Hafstad, PE5
Sandbakken, P5
Berstad, A3
Nesland, A1
Nyrén, O1
Adami, HO1
Bates, S1
Bergström, R1
Gustavsson, S1
Lööf, L1
Nyberg, A1
Talley, NJ1
McNeil, D1
Hayden, A1
Piper, DW1
Rappaport, BS1
Lance, P1
Wastell, C1
Scobie, IN1
Saunders, J1
Barnes, GD1
Hoad, J1
Wheeler, MJ1
Lowry, C1
Sonksen, PH1
Amphlett, G1
Riley, AJ1
Nesland, AA2
Serck-Hanssen, A1
Larsen, S3
Sandvik, L3
Kelbaek, H1
Linde, J1
Eriksen, J1
Mungaard, S1
Moesgaard, F1
Bonnevie, O1
Johannesen, T1
Pettersen, H1

Reviews

6 reviews available for cimetidine and Dyspepsia

ArticleYear
[25 years of gastric acid blockers].
    Nederlands tijdschrift voor geneeskunde, 1999, Dec-11, Volume: 143, Issue:50

    Topics: Anti-Ulcer Agents; Cimetidine; Dyspepsia; Gastroesophageal Reflux; Histamine H2 Antagonists; Humans;

1999
Treatment of non-ulcer dyspepsia: a meta-analysis of placebo-controlled prospective studies.
    Scandinavian journal of gastroenterology, 2001, Volume: 36, Issue:9

    Topics: Cimetidine; Cisapride; Domperidone; Dyspepsia; Gastrointestinal Agents; Histamine H2 Antagonists; Hu

2001
H2-receptor antagonists in the treatment of functional (nonulcer) dyspepsia: a meta-analysis of randomized controlled clinical trials.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:9

    Topics: Cimetidine; Dyspepsia; Histamine H2 Antagonists; Humans; Pain; Randomized Controlled Trials as Topic

2001
Role of sucralfate in peptic disease.
    Digestive diseases (Basel, Switzerland), 1992, Volume: 10, Issue:3

    Topics: Cimetidine; Dyspepsia; Esophagitis, Peptic; Gastritis; Humans; Peptic Ulcer; Ranitidine; Recurrence;

1992
The clinical relevance of endoscopic and histologic inflammation of gastroduodenal mucosa in dyspepsia of unknown origin.
    Scandinavian journal of gastroenterology, 1989, Volume: 24, Issue:4

    Topics: Adult; Antacids; Cimetidine; Duodenitis; Duodenoscopy; Dyspepsia; Female; Gastric Acid; Gastric Muco

1989
Bismuth: effects on gastritis and peptic ulcer.
    Scandinavian journal of gastroenterology. Supplement, 1988, Volume: 142

    Topics: Cimetidine; Duodenal Ulcer; Dyspepsia; Gastritis; Humans; Organometallic Compounds; Peptic Ulcer; Re

1988

Trials

31 trials available for cimetidine and Dyspepsia

ArticleYear
Efficacy and safety of ecabet sodium on functional dyspepsia: a prospective, double-blinded, randomized, multi-center controlled trial.
    World journal of gastroenterology, 2006, May-07, Volume: 12, Issue:17

    Topics: Abietanes; Adult; Age Factors; Anti-Ulcer Agents; Cimetidine; Double-Blind Method; Dyspepsia; Female

2006
Comparison of the effectiveness of geranylgeranylacetone with cimetidine in gastritis patients with dyspeptic symptoms and gastric lesions: a randomized, double-blind trial in Japan.
    Digestion, 2007, Volume: 75, Issue:4

    Topics: Anti-Ulcer Agents; Cimetidine; Diterpenes; Double-Blind Method; Dyspepsia; Female; Gastritis; Gastro

2007
Five-year study of cimetidine or surgery for severe duodenal ulcer dyspepsia.
    Lancet (London, England), 1982, Apr-03, Volume: 1, Issue:8275

    Topics: Cimetidine; Clinical Trials as Topic; Double-Blind Method; Duodenal Ulcer; Dyspepsia; Female; Follow

1982
[Cimetidine therapy in radio-negative dyspepsia].
    Ugeskrift for laeger, 1983, Oct-03, Volume: 145, Issue:40

    Topics: Adolescent; Adult; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Dyspepsia; Female; Hum

1983
[The histological picture of the gastric and duodenal mucosa in X-ray negative dyspepsia. Before and after treatment with cimetidine].
    Ugeskrift for laeger, 1984, Dec-17, Volume: 146, Issue:51

    Topics: Adolescent; Adult; Cimetidine; Duodenum; Dyspepsia; Female; Gastric Mucosa; Humans; Intestinal Mucos

1984
Comparison of sucralfate with cimetidine in the short-term treatment of chronic peptic ulcers.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1980, Apr-12, Volume: 57, Issue:15

    Topics: Adult; Aluminum; Antacids; Cimetidine; Clinical Trials as Topic; Disaccharides; Drug Evaluation; Duo

1980
The relationship between active peptic ulcer, endoscopic duodenitis and symptomatic state after treatment with cimetidine.
    Annals of clinical research, 1980, Volume: 12, Issue:1

    Topics: Adolescent; Adult; Cimetidine; Clinical Trials as Topic; Creatinine; Double-Blind Method; Duodenitis

1980
Cisapride or cimetidine in the treatment of functional dyspepsia. Results of a double-blind, randomized, Swiss multicentre study.
    Scandinavian journal of gastroenterology, 1994, Volume: 29, Issue:7

    Topics: Adult; Cimetidine; Cisapride; Double-Blind Method; Dyspepsia; Female; Humans; Male; Piperidines; Tre

1994
Clinical evaluation of the effect of omeprazole, cimetidine, famotidine and ranitidine on histamine induced cutaneous wheal and flare response.
    International journal of clinical pharmacology, therapy, and toxicology, 1993, Volume: 31, Issue:7

    Topics: Adult; Cimetidine; Drug Hypersensitivity; Dyspepsia; Famotidine; Female; Histamine; Histamine H2 Ant

1993
A randomised controlled trial of four management strategies for dyspepsia: relationships between symptom subgroups and strategy outcome.
    The British journal of general practice : the journal of the Royal College of General Practitioners, 2001, Volume: 51, Issue:469

    Topics: Anti-Ulcer Agents; Cimetidine; Cisapride; Clinical Protocols; Dyspepsia; Endoscopy, Gastrointestinal

2001
Helicobacter pylori eradication in patients on long-term H2 receptor antagonists. Economic and symptomatic benefits. A large prospective study in primary care.
    Helicobacter, 2002, Volume: 7, Issue:2

    Topics: Cimetidine; Cost Savings; Dyspepsia; Female; Follow-Up Studies; Gastric Acid; Gastritis; Helicobacte

2002
Long term cimetidine in the management of severe duodenal ulcer dyspepsia.
    Gastroenterology, 1978, Volume: 74, Issue:2 Pt 2

    Topics: Adult; Chronic Disease; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Duodenal Ulcer; D

1978
Cimetidine on-demand in dyspepsia. Experience with randomized controlled single-subject trials.
    Scandinavian journal of gastroenterology, 1992, Volume: 27, Issue:3

    Topics: Adult; Aged; Cimetidine; Confidence Intervals; Double-Blind Method; Dyspepsia; Esophagitis; Humans;

1992
The symptomatic effect of 1-day treatment periods with cimetidine in dyspepsia. Combined results from randomized, controlled, single-subject trials.
    Scandinavian journal of gastroenterology, 1991, Volume: 26, Issue:9

    Topics: Adult; Age Factors; Cimetidine; Double-Blind Method; Dyspepsia; Endoscopy, Gastrointestinal; Esophag

1991
Cimetidine in the treatment of non-ulcer dyspepsia: results of a randomized double-blind, placebo-controlled study.
    Current medical research and opinion, 1989, Volume: 11, Issue:6

    Topics: Adolescent; Adult; Aged; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Dyspepsia; Femal

1989
The clinical relevance of endoscopic and histologic inflammation of gastroduodenal mucosa in dyspepsia of unknown origin.
    Scandinavian journal of gastroenterology, 1989, Volume: 24, Issue:4

    Topics: Adult; Antacids; Cimetidine; Duodenitis; Duodenoscopy; Dyspepsia; Female; Gastric Acid; Gastric Muco

1989
Chewable cimetidine versus chewable antacid in dyspepsia: which provides faster pain relief?
    Current medical research and opinion, 1989, Volume: 11, Issue:9

    Topics: Administration, Oral; Adult; Aged; Antacids; Cimetidine; Double-Blind Method; Dyspepsia; Female; Hum

1989
Lack of therapeutic effect of cimetidine in non-ulcer dyspepsia.
    JPMA. The Journal of the Pakistan Medical Association, 1988, Volume: 38, Issue:6

    Topics: Adolescent; Adult; Cimetidine; Clinical Trials as Topic; Dyspepsia; Female; Humans; Male; Middle Age

1988
Treatment with cimetidine, antacid, or placebo in patients with dyspepsia of unknown origin.
    Scandinavian journal of gastroenterology, 1988, Volume: 23, Issue:1

    Topics: Adolescent; Adult; Aged; Antacids; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Dyspep

1988
Cimetidine responders in non-ulcer dyspepsia.
    Scandinavian journal of gastroenterology, 1988, Volume: 23, Issue:3

    Topics: Adult; Aged; Cimetidine; Clinical Trials as Topic; Dyspepsia; Female; Humans; Male; Middle Aged

1988
Absence of therapeutic benefit from antacids or cimetidine in non-ulcer dyspepsia.
    The New England journal of medicine, 1986, Feb-06, Volume: 314, Issue:6

    Topics: Adolescent; Adult; Antacids; Chronic Disease; Cimetidine; Clinical Trials as Topic; Double-Blind Met

1986
Cimetidine and non-ulcer dyspepsia.
    Drug and therapeutics bulletin, 1986, Jan-13, Volume: 24, Issue:1

    Topics: Cimetidine; Clinical Trials as Topic; Dyspepsia; Humans

1986
Randomized, double-blind, placebo-controlled crossover trial of cimetidine and pirenzepine in nonulcer dyspepsia.
    Gastroenterology, 1986, Volume: 91, Issue:1

    Topics: Adult; Aged; Benzodiazepinones; Cimetidine; Clinical Trials as Topic; Dyspepsia; Female; Humans; Mal

1986
Absence of therapeutic benefit from antacids or cimetidine in non-ulcer dyspepsia.
    The New England journal of medicine, 1986, Sep-18, Volume: 315, Issue:12

    Topics: Antacids; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Dyspepsia; Humans; Random Alloc

1986
A controlled trial of cimetidine for the treatment of nonulcer dyspepsia.
    Journal of clinical gastroenterology, 1986, Volume: 8, Issue:4

    Topics: Adult; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Duodenitis; Dyspepsia; Female; Hum

1986
A comparative study of the effects of ranitidine and cimetidine on carbohydrate tolerance, growth hormone secretion and the hypothalamic-pituitary-gonadal axis in man.
    Current medical research and opinion, 1986, Volume: 10, Issue:5

    Topics: Adult; Blood Glucose; Cimetidine; Dyspepsia; Glucose Tolerance Test; Gonadal Steroid Hormones; Growt

1986
The effect of cimetidine in non-ulcer dyspepsia. Experience with a multi-cross-over model.
    Scandinavian journal of gastroenterology, 1985, Volume: 20, Issue:1

    Topics: Adult; Aged; Cimetidine; Clinical Trials as Topic; Dyspepsia; Female; Humans; Male; Middle Aged; Pla

1985
Controlled clinical trial of treatment with cimetidine for non-ulcer dyspepsia.
    Acta medica Scandinavica, 1985, Volume: 217, Issue:3

    Topics: Adolescent; Adult; Aged; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Dyspepsia; Femal

1985
Effect of cimetidine in patients with non-ulcer dyspepsia and erosive prepyloric changes.
    Scandinavian journal of gastroenterology, 1985, Volume: 20, Issue:5

    Topics: Adult; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Dyspepsia; Female; Gastric Mucosa;

1985
Controlled trials in gastrodyspepsia: a methodological aspect.
    Scandinavian journal of gastroenterology. Supplement, 1985, Volume: 109

    Topics: Cimetidine; Clinical Trials as Topic; Drug Administration Schedule; Drug Evaluation; Dyspepsia; Huma

1985
[Cimetidine in non-ulcer dyspepsia. Preliminary results with a multi-crossover model].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1985, Aug-20, Volume: 105, Issue:23

    Topics: Adult; Aged; Cimetidine; Clinical Trials as Topic; Dyspepsia; Female; Humans; Male; Middle Aged; Pep

1985

Other Studies

22 other studies available for cimetidine and Dyspepsia

ArticleYear
Hypocalcemic tetany associated with simultaneous administration of cimetidine and nifedipine: a case report.
    Journal of medical case reports, 2023, Jul-28, Volume: 17, Issue:1

    Topics: Calcium Gluconate; Cimetidine; Dyspepsia; Female; Humans; Hypocalcemia; Middle Aged; Nifedipine; Spa

2023
Clinical pharmacokinetic drug interaction studies of gabapentin enacarbil, a novel transported prodrug of gabapentin, with naproxen and cimetidine.
    British journal of clinical pharmacology, 2010, Volume: 69, Issue:5

    Topics: Adolescent; Adult; Biological Transport; Carbamates; Cimetidine; Constipation; Dose-Response Relatio

2010
Effect of cimetidine on gastric juice N-nitrosamine concentration.
    Lancet (London, England), 1981, Sep-12, Volume: 2, Issue:8246

    Topics: Achlorhydria; Adolescent; Adult; Aged; Bacteria; Cimetidine; Digestive System; Dyspepsia; Fasting; F

1981
Cimetidine for dyspepsia?
    Lancet (London, England), 1984, Aug-04, Volume: 2, Issue:8397

    Topics: Cimetidine; Dyspepsia; Humans

1984
The use of one gram daily cimetidine in the treatment of peptic ulcer in Singapore.
    Annals of the Academy of Medicine, Singapore, 1983, Volume: 12, Issue:4

    Topics: Adult; Aged; Cimetidine; Drug Evaluation; Duodenal Ulcer; Dyspepsia; Female; Humans; Male; Middle Ag

1983
Cimetidine-induced interstitial nephritis with response to prednisone therapy.
    Archives of internal medicine, 1983, Volume: 143, Issue:4

    Topics: Acute Disease; Aged; Cimetidine; Dyspepsia; Female; Guanidines; Humans; Nephritis, Interstitial; Pre

1983
Cimetidine for recurrent ulcer after gastric surgery.
    Journal of clinical gastroenterology, 1983, Volume: 5, Issue:2

    Topics: Adult; Aged; Cimetidine; Dyspepsia; Female; Follow-Up Studies; Gastrectomy; Gastrins; Gastroscopy; G

1983
The treatment of peptic ulcer.
    The New Zealand medical journal, 1982, Nov-24, Volume: 95, Issue:720

    Topics: Anti-Ulcer Agents; Bismuth; Cimetidine; Diagnosis, Differential; Dyspepsia; Humans; Organometallic C

1982
[Costs and effectiveness of diagnosis and treatment of patients with dyspepsia, determined with the aid of a computer model].
    Nederlands tijdschrift voor geneeskunde, 1993, Aug-28, Volume: 137, Issue:35

    Topics: Bismuth; Cimetidine; Clinical Protocols; Computer Simulation; Cost-Benefit Analysis; Drug Therapy, C

1993
Cost effectiveness of screening for and eradication of Helicobacter pylori in young patients with dyspepsia. Studies'assumptions are removed from clinical practice.
    BMJ (Clinical research ed.), 1996, Sep-07, Volume: 313, Issue:7057

    Topics: Anti-Ulcer Agents; Cimetidine; Drug Costs; Dyspepsia; Endoscopy, Gastrointestinal; Helicobacter Infe

1996
Gastric cancer in patients who have taken cimetidine.
    Lancet (London, England), 1979, Jun-30, Volume: 1, Issue:8131

    Topics: Cimetidine; Dyspepsia; Guanidines; Humans; Stomach Neoplasms

1979
[Effect of cimetidine on gastric secretion in the interdigestive phase and after pentagastrin stimulation in patients with dyspepsia].
    Bollettino della Societa italiana di biologia sperimentale, 1978, Apr-15, Volume: 54, Issue:7

    Topics: Adult; Cimetidine; Dyspepsia; Female; Gastric Acidity Determination; Gastric Juice; Guanidines; Huma

1978
The treatment of dyspepsia.
    Australian family physician, 1977, Volume: 6, Issue:8

    Topics: Antacids; Bismuth; Carbenoxolone; Cimetidine; Dyspepsia; Esophagitis; Humans; Metoclopramide; Parasy

1977
Cimetidine therapy and duodenal candidiasis: role in healing process.
    Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 1992, Volume: 11, Issue:1

    Topics: Candidiasis; Cimetidine; Colony Count, Microbial; Duodenal Diseases; Duodenal Ulcer; Dyspepsia; Fema

1992
Controlled trials in single subjects. 1. Value in clinical medicine.
    BMJ (Clinical research ed.), 1991, Jul-20, Volume: 303, Issue:6795

    Topics: Cimetidine; Dyspepsia; Humans; Patient Compliance; Physician-Patient Relations; Placebo Effect; Rand

1991
Non-ulcer dyspepsia.
    Lancet (London, England), 1986, Jul-12, Volume: 2, Issue:8498

    Topics: Cimetidine; Dyspepsia; Gastric Mucosa; Humans

1986
Management of dyspepsia: report of a working party.
    Lancet (London, England), 1988, Mar-12, Volume: 1, Issue:8585

    Topics: Adult; Antacids; Bismuth; Cimetidine; Diagnosis, Differential; Domperidone; Dyspepsia; Histamine H2

1988
Choice of non-steroidal anti-inflammatory drug in persons treated for dyspepsia.
    Lancet (London, England), 1988, Sep-03, Volume: 2, Issue:8610

    Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics; Antacids; Anti-Inflammatory Agents, Non-Steroida

1988
Experience with a multi crossover model in dyspepsia.
    Scandinavian journal of gastroenterology. Supplement, 1988, Volume: 147

    Topics: Cimetidine; Clinical Trials as Topic; Data Interpretation, Statistical; Dyspepsia; Humans; Medical R

1988
Dyspepsia: Therapeutic response as a diagnostic tool.
    Scandinavian journal of gastroenterology. Supplement, 1987, Volume: 128

    Topics: Cimetidine; Dyspepsia; Gastric Acid; Humans; Pilot Projects

1987
Erosive prepyloric changes (EPC)--a new entity.
    Scandinavian journal of gastroenterology. Supplement, 1987, Volume: 128

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Cimetidine; Double-Blind Method; Dyspepsia; Gastr

1987
Histological findings in erosive prepyloric changes.
    Scandinavian journal of gastroenterology, 1986, Volume: 21, Issue:2

    Topics: Biopsy; Cimetidine; Dyspepsia; Endoscopy; Gastric Mucosa; Humans; Inflammation; Pylorus

1986