cimetidine has been researched along with Diarrhea in 29 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Diarrhea: An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fifty consecutive patients with symptomatic endoscopically proven duodenal ulcer were randomized double-blind to Mylanta II or cimetidine treatment schedules." | 9.05 | Influence of smoking on healing rate of duodenal ulcer in response to cimetidine or high-dose antacid. ( Hansky, J; Korman, MG; Schmidt, GT; Shaw, RG; Stern, AI, 1981) |
| "In a randomized double blind multicenter trial, patients treated with cimetidine (800 or 1200 mg daily) or an intensive regimen of Al-Mg antacid (210 ml daily) had similar rates of duodenal ulcer healing and pain relief." | 9.04 | Cimetidine versus intensive antacid therapy for duodenal ulcer: a multicenter trial. ( Binder, M; Camacho, R; Cano, R; Cooney, C; Ippoliti, AF; Isenberg, JI; Kline, MM; Koretz, RL; Meyer, JH; Samloff, IM; Schwabe, AD; Strom, EA; Sturdevant, RA; Valenzuela, JE; Wintroub, RH, 1978) |
| "Two hundred forty patients with benign gastric ulcer were treated in a controlled clinical trial to assess the effect on healing of cimetidine, antacids, and hospitalization." | 9.04 | Cimetidine, antacid, and hospitalization in the treatment of benign gastric ulcer: a multicenter double blind study. ( Crossley, RJ; Englert, E; Finkelstein, W; Freston, JW; Graham, DY; Kruss, DM; Priest, RJ; Raskin, JB; Rhodes, JB; Rogers, AI; Wenger, J; Wilcox, LL, 1978) |
| "Cimetidine and ranitidine are specific and potent H2-receptor antagonists widely used in the effective therapy of peptic ulcer disease." | 8.77 | Actions of cimetidine and ranitidine at some cholinergic sites: implications in toxicology and anesthesia. ( Cheah, LS; Gwee, MC, 1986) |
| " The misoprostol healing rates obtained in duodenal ulcer and gastric ulcer therapy at 200 micrograms qid are not significantly different from those seen in the same studies with cimetidine at a dose of 300 mg qid." | 6.15 | Overview of misoprostol clinical experience. ( Herting, RL; Nissen, CH, 1986) |
| "HCl/hr." | 5.26 | A case of Brunner's glands hyperplasia with diarrhea responsive to cimetidine. ( Spellberg, MA; Vucelic, B, 1980) |
| "Fifty consecutive patients with symptomatic endoscopically proven duodenal ulcer were randomized double-blind to Mylanta II or cimetidine treatment schedules." | 5.05 | Influence of smoking on healing rate of duodenal ulcer in response to cimetidine or high-dose antacid. ( Hansky, J; Korman, MG; Schmidt, GT; Shaw, RG; Stern, AI, 1981) |
| "In a randomized double blind multicenter trial, patients treated with cimetidine (800 or 1200 mg daily) or an intensive regimen of Al-Mg antacid (210 ml daily) had similar rates of duodenal ulcer healing and pain relief." | 5.04 | Cimetidine versus intensive antacid therapy for duodenal ulcer: a multicenter trial. ( Binder, M; Camacho, R; Cano, R; Cooney, C; Ippoliti, AF; Isenberg, JI; Kline, MM; Koretz, RL; Meyer, JH; Samloff, IM; Schwabe, AD; Strom, EA; Sturdevant, RA; Valenzuela, JE; Wintroub, RH, 1978) |
| "Two hundred forty patients with benign gastric ulcer were treated in a controlled clinical trial to assess the effect on healing of cimetidine, antacids, and hospitalization." | 5.04 | Cimetidine, antacid, and hospitalization in the treatment of benign gastric ulcer: a multicenter double blind study. ( Crossley, RJ; Englert, E; Finkelstein, W; Freston, JW; Graham, DY; Kruss, DM; Priest, RJ; Raskin, JB; Rhodes, JB; Rogers, AI; Wenger, J; Wilcox, LL, 1978) |
| "Cimetidine and ranitidine are specific and potent H2-receptor antagonists widely used in the effective therapy of peptic ulcer disease." | 4.77 | Actions of cimetidine and ranitidine at some cholinergic sites: implications in toxicology and anesthesia. ( Cheah, LS; Gwee, MC, 1986) |
| " Treatment with cimetidine (H2 receptor antagonist) resulted in diarrhea, however, the addition of cyproheptadine (H1 receptor antagonist) was beneficial in amelioration of the cutaneous symptoms of mastocytosis." | 3.68 | Systemic mastocytosis treated with histamine H1 and H2 receptor antagonists. ( Falk, ES; Gasior-Chrzan, B, 1992) |
| " In our patient, a 34-year-old man with poorly controlled type 1 diabetes and autonomic neuropathy manifested by postural hypotension and diarrhea, treatment with diphenhydramine and cimetidine (H1 and H2 histamine antagonists, respectively) markedly improved the hypotension and diarrhea and led to better blood glucose control." | 3.66 | Combination H1 and H2 receptor antagonist therapy in diabetic autonomic neuropathy. ( Robertson, D; Stacpoole, PW, 1982) |
| "Diarrhea is the most common complication and occurs more frequently in patients who receive antacids." | 1.28 | Nonhemorrhagic gastrointestinal complications in acute respiratory failure. ( Dark, DS; Pingleton, SK, 1989) |
| "A patient with acquired immune deficiency syndrome who developed symptoms of partial gastric outlet obstruction during the course of a severe diarrheal illness due to cryptosporidiosis is presented." | 1.27 | Cryptosporidiosis of the stomach. ( Garone, MA; Lewis, JH; Winston, BJ, 1986) |
| "A symptomatic recurrence was controlled with the addition of propantheline." | 1.26 | The effect of cimetidine and propantheline on the symptoms of a patient with systemic mastocytosis. ( Achord, JL; Langford, H, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (89.66) | 18.7374 |
| 1990's | 3 (10.34) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aly, A | 1 |
| Bárány, F | 1 |
| Kollberg, B | 1 |
| Monsén, U | 1 |
| Wisén, O | 1 |
| Johansson, C | 1 |
| Stacpoole, PW | 1 |
| Robertson, D | 1 |
| Becker, HD | 1 |
| de la Pierre, M | 1 |
| Aricò, S | 1 |
| Capussotti, L | 1 |
| Dellepiane, M | 1 |
| Marucci, M | 1 |
| Gandini, G | 1 |
| Imarisio, P | 1 |
| Achord, JL | 1 |
| Langford, H | 1 |
| Kelly, TW | 1 |
| Patrick, MR | 1 |
| Hillman, KM | 1 |
| Ewe, K | 1 |
| Vantrappen, G | 1 |
| Janssens, J | 1 |
| Popiela, T | 1 |
| Kulig, J | 1 |
| Tytgat, GN | 1 |
| Huibregtse, K | 1 |
| Lambert, R | 1 |
| Pauchard, JP | 1 |
| Robert, A | 1 |
| Korman, MG | 1 |
| Shaw, RG | 1 |
| Hansky, J | 1 |
| Schmidt, GT | 1 |
| Stern, AI | 1 |
| Spellberg, MA | 1 |
| Vucelic, B | 1 |
| Ruddell, WS | 1 |
| Losowsky, MS | 1 |
| Naveh, Y | 1 |
| Kleinhaus, U | 1 |
| Kerner, E | 1 |
| Berant, M | 1 |
| Duncan, HD | 1 |
| Talbot, IC | 1 |
| Silk, DB | 1 |
| Voget, E | 1 |
| Schollmeyer, P | 1 |
| Ippoliti, AF | 1 |
| Sturdevant, RA | 1 |
| Isenberg, JI | 1 |
| Binder, M | 1 |
| Camacho, R | 1 |
| Cano, R | 1 |
| Cooney, C | 1 |
| Kline, MM | 1 |
| Koretz, RL | 1 |
| Meyer, JH | 1 |
| Samloff, IM | 1 |
| Schwabe, AD | 1 |
| Strom, EA | 1 |
| Valenzuela, JE | 1 |
| Wintroub, RH | 1 |
| Englert, E | 1 |
| Freston, JW | 1 |
| Graham, DY | 1 |
| Finkelstein, W | 1 |
| Kruss, DM | 1 |
| Priest, RJ | 1 |
| Raskin, JB | 1 |
| Rhodes, JB | 1 |
| Rogers, AI | 1 |
| Wenger, J | 1 |
| Wilcox, LL | 1 |
| Crossley, RJ | 1 |
| Hirschowitz, BI | 1 |
| Groarke, JF | 1 |
| Theodore, C | 1 |
| Mendez, J | 1 |
| Paolaggi, JA | 1 |
| Field, R | 1 |
| Meyer, GW | 1 |
| Gasior-Chrzan, B | 1 |
| Falk, ES | 1 |
| Dark, DS | 1 |
| Pingleton, SK | 1 |
| Gwee, MC | 1 |
| Cheah, LS | 1 |
| Raimes, SA | 1 |
| Smirniotis, V | 1 |
| Wheldon, EJ | 1 |
| Venables, CW | 1 |
| Johnston, ID | 1 |
| Herting, RL | 2 |
| Nissen, CH | 1 |
| Yoshikawa, H | 1 |
| Kawai, K | 1 |
| Inoue, S | 1 |
| Murayama, Y | 1 |
| Kuzuya, N | 1 |
| Fujita, T | 1 |
| Koide, Y | 1 |
| Yamashita, K | 1 |
| Yoshizawa, K | 1 |
| Mizusawa, H | 1 |
| Garone, MA | 1 |
| Winston, BJ | 1 |
| Lewis, JH | 1 |
| Achkar, E | 1 |
| Clay, GA | 1 |
| Serrano Sánchez, PA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparing Buccal and Vaginal Misoprostol in Management of Early Pregnancy Loss: a Pilot Randomized Controlled Trial[NCT02141555] | Phase 2/Phase 3 | 4 participants (Actual) | Interventional | 2014-08-31 | Completed | ||
| Immune Modulation by Misoprostol[NCT02259309] | Early Phase 1 | 15 participants (Actual) | Interventional | 2014-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Assessment of medication side effects including: nausea, vomiting, headache, fever (over 100.4 F), dizziness, diarrhea, bad taste, dry mouth Did you experience any of these side effects? If so, how long did they last?~Patients asked on a scale of 0 to 3, where:~Side Effect scale:~0 = never~1= less than one day 2 = 1 to 2 days 3 = more than 2 days" (NCT02141555)
Timeframe: one week
| Intervention | Participants (Count of Participants) |
|---|---|
| Vaginal Misoprostol | 0 |
| Buccal Misoprostol | 0 |
"Written surveys patients will fill out at follow up visit assessing patient's satisfaction with the procedure.~How satisfied were you with your procedure?~The satisfaction scale used was:~1 =Very Satisfied, comfortable, likely to recommend 3= Neutral 5= Very unsatisfied/uncomfortable, unlike to recommend" (NCT02141555)
Timeframe: one week
| Intervention | Participants (Count of Participants) |
|---|---|
| Vaginal Misoprostol | 2 |
| Buccal Misoprostol | 2 |
Number of participants with complete abortion without surgical intervention defined as no evidence of a gestational sac on transvaginal ultrasound at the follow up visit. (NCT02141555)
Timeframe: one week
| Intervention | Participants (Count of Participants) |
|---|---|
| Vaginal Misoprostol | 1 |
| Buccal Misoprostol | 2 |
The percentage of women who are offered enrollment and accept. (NCT02141555)
Timeframe: One year
| Intervention | Participants (Count of Participants) |
|---|---|
| Vaginal Misoprostol | 2 |
| Buccal Misoprostol | 2 |
4 reviews available for cimetidine and Diarrhea
| Article | Year |
|---|---|
[Zollinger-Ellison syndrome].
Topics: Benzimidazoles; Calcium; Cimetidine; Diarrhea; Duodenal Ulcer; Female; Fluorouracil; Gastrectomy; Ga | 1984 |
[The therapeutic importance of cimetidine (Tagamet) (author's transl)].
Topics: Adult; Cimetidine; Diarrhea; Female; Galactorrhea; Gastritis; Guanidines; Gynecomastia; Headache; Hu | 1978 |
Actions of cimetidine and ranitidine at some cholinergic sites: implications in toxicology and anesthesia.
Topics: Anesthesia; Animals; Antihypertensive Agents; Bradycardia; Cholinesterase Inhibitors; Cimetidine; Co | 1986 |
Overview of misoprostol clinical experience.
Topics: Alprostadil; Anti-Ulcer Agents; Cimetidine; Clinical Trials as Topic; Diarrhea; Duodenal Ulcer; Fema | 1986 |
7 trials available for cimetidine and Diarrhea
| Article | Year |
|---|---|
Effect of an H2-receptor blocking agent on diarrhoeas after extensive small bowel resection in Crohn's disease.
Topics: Adult; Cimetidine; Crohn Disease; Defecation; Diarrhea; Double-Blind Method; Feces; Female; Guanidin | 1980 |
Effect of 15(R)-15-methyl prostaglandin E2 (arbaprostil) on the healing of duodenal ulcer: a double-blind multicenter study.
Topics: Adolescent; Adult; Aged; Arbaprostil; Cimetidine; Clinical Trials as Topic; Diarrhea; Double-Blind M | 1982 |
Influence of smoking on healing rate of duodenal ulcer in response to cimetidine or high-dose antacid.
Topics: Adolescent; Adult; Aged; Aluminum Hydroxide; Antacids; Cimetidine; Diarrhea; Double-Blind Method; Dr | 1981 |
Cimetidine versus intensive antacid therapy for duodenal ulcer: a multicenter trial.
Topics: Adult; Antacids; Cimetidine; Clinical Trials as Topic; Diarrhea; Double-Blind Method; Duodenal Ulcer | 1978 |
Cimetidine, antacid, and hospitalization in the treatment of benign gastric ulcer: a multicenter double blind study.
Topics: Adult; Aged; Antacids; Cimetidine; Clinical Trials as Topic; Diarrhea; Double-Blind Method; Female; | 1978 |
Overview of misoprostol clinical experience.
Topics: Alprostadil; Anti-Ulcer Agents; Cimetidine; Clinical Trials as Topic; Diarrhea; Duodenal Ulcer; Fema | 1986 |
Overview of clinical safety with misoprostol.
Topics: Alprostadil; Anti-Ulcer Agents; Biopsy; Cimetidine; Clinical Trials as Topic; Diarrhea; Double-Blind | 1985 |
Overview of clinical safety with misoprostol.
Topics: Alprostadil; Anti-Ulcer Agents; Biopsy; Cimetidine; Clinical Trials as Topic; Diarrhea; Double-Blind | 1985 |
Overview of clinical safety with misoprostol.
Topics: Alprostadil; Anti-Ulcer Agents; Biopsy; Cimetidine; Clinical Trials as Topic; Diarrhea; Double-Blind | 1985 |
Overview of clinical safety with misoprostol.
Topics: Alprostadil; Anti-Ulcer Agents; Biopsy; Cimetidine; Clinical Trials as Topic; Diarrhea; Double-Blind | 1985 |
19 other studies available for cimetidine and Diarrhea
| Article | Year |
|---|---|
Combination H1 and H2 receptor antagonist therapy in diabetic autonomic neuropathy.
Topics: Adult; Cimetidine; Diabetic Neuropathies; Diarrhea; Diphenhydramine; Drug Therapy, Combination; Hist | 1982 |
[Description of a case of Zollinger-Ellison syndrome].
Topics: Benzodiazepinones; Body Weight; Cimetidine; Diarrhea; Female; Gastrectomy; Gastric Acid; Humans; Mid | 1984 |
The effect of cimetidine and propantheline on the symptoms of a patient with systemic mastocytosis.
Topics: Adult; Celiac Disease; Cimetidine; Diarrhea; Female; Gastric Juice; Guanidines; Humans; Pepsin A; Pr | 1980 |
Study of diarrhea in critically ill patients.
Topics: Anti-Bacterial Agents; Cimetidine; Critical Care; Diarrhea; Female; Food, Formulated; Humans; Intuba | 1983 |
[Preventive measures in gastroenterology].
Topics: Cimetidine; Colonic Neoplasms; Diarrhea; Doxycycline; Esophageal and Gastric Varices; Gastrointestin | 1981 |
A case of Brunner's glands hyperplasia with diarrhea responsive to cimetidine.
Topics: Brunner Glands; Cimetidine; Diarrhea; Duodenum; Female; Guanidines; Humans; Hyperplasia; Middle Aged | 1980 |
Severe diarrehoea due to small intestinal colonisation during cimetidine treatment.
Topics: Aged; Bacteria; Cimetidine; Diarrhea; Female; Guanidines; Humans; Intestine, Small | 1980 |
Nonspecific duodenitis: an unusual presentation.
Topics: Abdominal Pain; Adolescent; Anti-Ulcer Agents; Child; Cimetidine; Diarrhea; Duodenitis; Duodenum; En | 1997 |
Collagenous colitis and cimetidine.
Topics: Antidiarrheals; Biopsy; Cimetidine; Colitis; Collagen; Diarrhea; Humans; Male; Middle Aged | 1997 |
Effect of cimetidine on gastric hypersecretion and diarrhea in systemic mastocytosis.
Topics: Adult; Cimetidine; Diarrhea; Female; Gastric Juice; Guanidines; Histamine Antagonists; Humans; Male; | 1979 |
[Diarrhea during cimetidine treatment].
Topics: Cimetidine; Dehydration; Diarrhea; Esophagitis, Peptic; Female; Guanidines; Humans; Male; Middle Age | 1979 |
Diarrhea from cimetidine [letrrr].
Topics: Cimetidine; Diarrhea; Guanidines; Humans; Male; Middle Aged | 1978 |
Systemic mastocytosis treated with histamine H1 and H2 receptor antagonists.
Topics: Biopsy; Cimetidine; Colon; Cyproheptadine; Diarrhea; Drug Therapy, Combination; Humans; Liver; Male; | 1992 |
Nonhemorrhagic gastrointestinal complications in acute respiratory failure.
Topics: Acute Disease; Antacids; Cimetidine; Diarrhea; Female; Gastrointestinal Diseases; Humans; Intensive | 1989 |
Postvagotomy diarrhoea put into perspective.
Topics: Adult; Aged; Cimetidine; Diarrhea; Duodenal Ulcer; Evaluation Studies as Topic; Follow-Up Studies; H | 1986 |
[A case of diabetic orthostatic hypotension effectively managed with L-dops (L-threo-3,4-dihydroxyphenylserine)].
Topics: Cimetidine; Diabetic Neuropathies; Diarrhea; Diphenhydramine; Droxidopa; Humans; Hypotension, Orthos | 1987 |
Cryptosporidiosis of the stomach.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antidiarrheals; Cimetidine; Cryptosporidiosis; Diarrhea; | 1986 |
Peptic ulcer disease: current management in the elderly.
Topics: Aged; Aluminum; Antacids; Antidepressive Agents; Cimetidine; Constipation; Diarrhea; Duodenal Ulcer; | 1985 |
[Gastrointestinal manifestations of systemic mastocytosis and its treatment with antagonists of H1 and H2 receptors. Experimental study].
Topics: Animals; Cimetidine; Diarrhea; Diphenhydramine; Duodenal Ulcer; Exocytosis; Female; Male; Rats; Stom | 1985 |