cimetidine has been researched along with Diabetic Neuropathies in 3 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Diabetic Neuropathies: Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325)
| Excerpt | Relevance | Reference |
|---|---|---|
| " In our patient, a 34-year-old man with poorly controlled type 1 diabetes and autonomic neuropathy manifested by postural hypotension and diarrhea, treatment with diphenhydramine and cimetidine (H1 and H2 histamine antagonists, respectively) markedly improved the hypotension and diarrhea and led to better blood glucose control." | 3.66 | Combination H1 and H2 receptor antagonist therapy in diabetic autonomic neuropathy. ( Robertson, D; Stacpoole, PW, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tachibana, M | 1 |
| Yamamura, N | 1 |
| Atiee, GJ | 1 |
| Hsu, C | 1 |
| Warren, V | 1 |
| He, L | 1 |
| Dishy, V | 1 |
| Zahir, H | 1 |
| Stacpoole, PW | 1 |
| Robertson, D | 1 |
| Yoshikawa, H | 1 |
| Kawai, K | 1 |
| Inoue, S | 1 |
| Murayama, Y | 1 |
| Kuzuya, N | 1 |
| Fujita, T | 1 |
| Koide, Y | 1 |
| Yamashita, K | 1 |
| Yoshizawa, K | 1 |
| Mizusawa, H | 1 |
1 trial available for cimetidine and Diabetic Neuropathies
| Article | Year |
|---|---|
Coadministration of probenecid and cimetidine with mirogabalin in healthy subjects: A phase 1, randomized, open-label, drug-drug interaction study.
Topics: Administration, Oral; Adult; Area Under Curve; Bridged Bicyclo Compounds; Cimetidine; Cross-Over Stu | 2018 |
2 other studies available for cimetidine and Diabetic Neuropathies
| Article | Year |
|---|---|
Combination H1 and H2 receptor antagonist therapy in diabetic autonomic neuropathy.
Topics: Adult; Cimetidine; Diabetic Neuropathies; Diarrhea; Diphenhydramine; Drug Therapy, Combination; Hist | 1982 |
[A case of diabetic orthostatic hypotension effectively managed with L-dops (L-threo-3,4-dihydroxyphenylserine)].
Topics: Cimetidine; Diabetic Neuropathies; Diarrhea; Diphenhydramine; Droxidopa; Humans; Hypotension, Orthos | 1987 |