cimetidine has been researched along with Dermatitis, Contact in 9 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Dermatitis, Contact: A type of acute or chronic skin reaction in which sensitivity is manifested by reactivity to materials or substances coming in contact with the skin. It may involve allergic or non-allergic mechanisms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Intravenous cimetidine treatment was prescribed for patients suffering from anaphylaxis, urticaria, pruritus, and contact dermatitis." | 7.67 | Intravenous cimetidine as an effective treatment for systemic anaphylaxis and acute allergic skin reactions. ( Asano, M; Au-Yong, TF; Kimura, S; Mayumi, H; Shimokawa, T; Yayama, T, 1987) |
| " Two H2 receptor antagonists, cimetidine and ranitidine, reversed the nonspecific immunosuppression of CS induced by burns." | 3.67 | The effect of histamine receptor antagonists on specific and nonspecific suppression of experimental contact sensitivity. ( Bender, EM; Claman, HN; Hansbrough, JF; Mekori, YA; Zapata-Sirvent, R, 1985) |
| "Intravenous cimetidine treatment was prescribed for patients suffering from anaphylaxis, urticaria, pruritus, and contact dermatitis." | 3.67 | Intravenous cimetidine as an effective treatment for systemic anaphylaxis and acute allergic skin reactions. ( Asano, M; Au-Yong, TF; Kimura, S; Mayumi, H; Shimokawa, T; Yayama, T, 1987) |
| "Treatment with cimetidine during the induction but not the elicitation of allergic contact hypersensitivity (ACH) produced a significant enhancement of the response throughout the first 48 h." | 1.28 | Cimetidine-induced augmentation of allergic contact hypersensitivity reactions in mice. ( Belsito, DV; Kerdel, FA; Potozkin, J; Soter, NA, 1990) |
| "Urticaria is caused by physical factors in almost 12 percent of cases." | 1.26 | Symptomatic dermographism. ( Estes, SA; Margolis, CF, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (55.56) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Lin, TK | 1 |
| Man, MQ | 1 |
| Santiago, JL | 1 |
| Park, K | 1 |
| Roelandt, T | 1 |
| Oda, Y | 1 |
| Hupe, M | 1 |
| Crumrine, D | 1 |
| Lee, HJ | 1 |
| Gschwandtner, M | 1 |
| Thyssen, JP | 1 |
| Trullas, C | 1 |
| Tschachler, E | 1 |
| Feingold, KR | 1 |
| Elias, PM | 1 |
| Margolis, CF | 1 |
| Estes, SA | 1 |
| Olafsson, JH | 1 |
| Granerus, G | 1 |
| Roupe, G | 1 |
| Bellavia, A | 1 |
| Bannera, AF | 1 |
| Marino, V | 1 |
| Arcoleo, V | 1 |
| Ferrara, D | 1 |
| Belsito, DV | 1 |
| Kerdel, FA | 1 |
| Potozkin, J | 1 |
| Soter, NA | 1 |
| Griswold, DE | 1 |
| Alessi, S | 1 |
| Badger, AM | 1 |
| Poste, G | 1 |
| Hanna, N | 1 |
| Mekori, YA | 1 |
| Bender, EM | 1 |
| Zapata-Sirvent, R | 1 |
| Hansbrough, JF | 1 |
| Claman, HN | 1 |
| Mayumi, H | 1 |
| Kimura, S | 1 |
| Asano, M | 1 |
| Shimokawa, T | 1 |
| Au-Yong, TF | 1 |
| Yayama, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Skin Barrier Dysfunction and the Role of Skin Barrier Restoration on Cutaneous and Systemic Inflammation in the Aged Population[NCT03728569] | Early Phase 1 | 14 participants (Actual) | Interventional | 2018-05-16 | Terminated (stopped due to Enrollment and interactions/interventions paused due to COVID-19. Not expected to resume in the future. This is not a suspension of IRB approval) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 other studies available for cimetidine and Dermatitis, Contact
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Topical antihistamines display potent anti-inflammatory activity linked in part to enhanced permeability barrier function.
Topics: Administration, Topical; Animals; Cell Differentiation; Cimetidine; Dermatitis, Atopic; Dermatitis, | 2013 |
Symptomatic dermographism.
Topics: Adult; Cimetidine; Dermatitis, Contact; Diagnosis, Differential; Histamine H1 Antagonists; Humans; M | 1981 |
Effect of antihistamins (H1 and H2), cortisone and beta-adrenergic stimulator on murine contact sensitivity and histamine metabolism.
Topics: Adrenergic beta-Agonists; Animals; Cimetidine; Clemastine; Dermatitis, Contact; Histamine; Histamine | 1983 |
In vivo cimetidine immunomodulatory effects on the cutaneous reaction to oxazolone in the chicken.
Topics: Adjuvants, Immunologic; Albumins; Animals; Antibody Formation; Arthus Reaction; B-Lymphocytes; Bursa | 1997 |
Cimetidine-induced augmentation of allergic contact hypersensitivity reactions in mice.
Topics: Animals; Cell Degranulation; Cimetidine; Dermatitis, Contact; Histamine; Mast Cells; Mice; Mice, Inb | 1990 |
Differential sensitivity of T suppressor cell expression to inhibition by histamine type 2 receptor antagonists.
Topics: Animals; Benzenesulfonates; Cimetidine; Dermatitis, Contact; Diphenhydramine; Dose-Response Relation | 1986 |
The effect of histamine receptor antagonists on specific and nonspecific suppression of experimental contact sensitivity.
Topics: Animals; Burns; Cimetidine; Dermatitis, Contact; Dinitrofluorobenzene; Female; Histamine Antagonists | 1985 |
Intravenous cimetidine as an effective treatment for systemic anaphylaxis and acute allergic skin reactions.
Topics: Acute Disease; Adolescent; Adult; Aged; Anaphylaxis; Child; Cimetidine; Dermatitis, Contact; Drug Ev | 1987 |