Page last updated: 2024-10-25

cimetidine and Dermatitis, Atopic

cimetidine has been researched along with Dermatitis, Atopic in 4 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Dermatitis, Atopic: A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lin, TK1
Man, MQ1
Santiago, JL1
Park, K1
Roelandt, T1
Oda, Y1
Hupe, M1
Crumrine, D1
Lee, HJ1
Gschwandtner, M1
Thyssen, JP1
Trullas, C1
Tschachler, E1
Feingold, KR1
Elias, PM1
Deutsch, PH1
Frosch, PJ1
Schwanitz, HJ1
Macher, E1
Foulds, IS1
MacKie, RM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Skin Barrier Dysfunction and the Role of Skin Barrier Restoration on Cutaneous and Systemic Inflammation in the Aged Population[NCT03728569]Early Phase 114 participants (Actual)Interventional2018-05-16Terminated (stopped due to Enrollment and interactions/interventions paused due to COVID-19. Not expected to resume in the future. This is not a suspension of IRB approval)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for cimetidine and Dermatitis, Atopic

ArticleYear
A double blind trial of H1 and H2 receptor antagonists in the treatment of atopic dermatitis.
    Archives of dermatological research, 1984, Volume: 276, Issue:1

    Topics: Adolescent; Adult; Chlorpheniramine; Cimetidine; Clinical Trials as Topic; Dermatitis, Atopic; Doubl

1984
A double-blind trial of the H2 receptor antagonist cimetidine, and the H1 receptor antagonist promethazine hydrochloride in the treatment of atopic dermatitis.
    Clinical allergy, 1981, Volume: 11, Issue:4

    Topics: Adolescent; Adult; Cimetidine; Clinical Trials as Topic; Dermatitis, Atopic; Double-Blind Method; Fe

1981

Other Studies

2 other studies available for cimetidine and Dermatitis, Atopic

ArticleYear
Topical antihistamines display potent anti-inflammatory activity linked in part to enhanced permeability barrier function.
    The Journal of investigative dermatology, 2013, Volume: 133, Issue:2

    Topics: Administration, Topical; Animals; Cell Differentiation; Cimetidine; Dermatitis, Atopic; Dermatitis,

2013
Dermatographism treated with hydroxyzine and cimetidine and ranitidine.
    Annals of internal medicine, 1984, Volume: 101, Issue:4

    Topics: Adult; Cimetidine; Dermatitis, Atopic; Drug Therapy, Combination; Humans; Hydroxyzine; Male; Pruritu

1984