cimetidine has been researched along with Depressive Disorder in 12 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Depressive Disorder: An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The cyclic adenosine monophosphate (cAMP) responses to histamine, prostaglandin-E1, and isoproterenol in polymorphonuclear leukocytes from drug-free normal controls and patients with schizophrenia or major depressive disorder were compared." | 3.67 | Cyclic-AMP production by polymorphonuclear leukocytes in psychiatric disorders. ( Coccaro, EF; Davidson, M; Davis, KL; Johns, CA; Kanof, PD; Siever, LJ, 1989) |
| "In view of the good tolerability of escitalopram, the pharmacokinetic changes observed on co-administration with cimetidine or omeprazole are unlikely to be of clinical concern." | 2.71 | The effect of cimetidine or omeprazole on the pharmacokinetics of escitalopram in healthy subjects. ( Malling, D; Poulsen, MN; Søgaard, B, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (83.33) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Malling, D | 1 |
| Poulsen, MN | 1 |
| Søgaard, B | 1 |
| Lerro, FA | 1 |
| Miller, DD | 2 |
| Sawyer, JB | 1 |
| Duffy, JP | 1 |
| Macklin, M | 1 |
| Crowder, MK | 2 |
| Billings, RF | 1 |
| Tang, SW | 1 |
| Rakoff, VM | 1 |
| Pate, JK | 1 |
| Leo, RJ | 1 |
| Lichter, DG | 1 |
| Hershey, LA | 1 |
| Kanof, PD | 1 |
| Coccaro, EF | 1 |
| Johns, CA | 1 |
| Davidson, M | 1 |
| Siever, LJ | 1 |
| Davis, KL | 1 |
| Goldstein, JA | 1 |
| Miller, ME | 1 |
| Perry, CJ | 1 |
| Siris, SG | 1 |
1 trial available for cimetidine and Depressive Disorder
| Article | Year |
|---|---|
The effect of cimetidine or omeprazole on the pharmacokinetics of escitalopram in healthy subjects.
Topics: Adolescent; Adult; Anti-Ulcer Agents; Cimetidine; Citalopram; Depressive Disorder; Drug Therapy, Com | 2005 |
11 other studies available for cimetidine and Depressive Disorder
| Article | Year |
|---|---|
Abdominal distention syndrome in a patient receiving cimetidine-nortriptyline therapy.
Topics: Cimetidine; Depressive Disorder; Drug Synergism; Female; Gastric Emptying; Gastritis; Humans; Middle | 1983 |
Cimetidine's effect on steady-state serum nortriptyline concentrations.
Topics: Cimetidine; Depressive Disorder; Drug Interactions; Humans; Male; Middle Aged; Nortriptyline; Peptic | 1983 |
Cimetidine-imipramine interaction: case report and comments.
Topics: Cimetidine; Depressive Disorder; Drug Interactions; Drug Therapy, Combination; Female; Humans; Imipr | 1984 |
Cimetidine-imipramine interaction: a case report.
Topics: Adult; Cimetidine; Depressive Disorder; Desipramine; Drug Interactions; Female; Guanidines; Half-Lif | 1983 |
Central nervous system side effects of cimetidine.
Topics: Cimetidine; Depressive Disorder; Guanidines; Humans; Male; Middle Aged | 1981 |
Depression associated with cimetidine.
Topics: Adult; Aged; Cimetidine; Depressive Disorder; Esophagitis, Peptic; Female; Guanidines; Humans; Male; | 1981 |
A case report of cimetidine-induce depressive syndrome.
Topics: Cimetidine; Depressive Disorder; Guanidines; Humans; Male; Middle Aged; Peptic Ulcer | 1980 |
Parkinsonism associated with fluoxetine and cimetidine: a case report.
Topics: Aged; Cimetidine; Depressive Disorder; Drug Therapy, Combination; Fluoxetine; Humans; Male; Parkinso | 1995 |
Cyclic-AMP production by polymorphonuclear leukocytes in psychiatric disorders.
Topics: Adult; Alprostadil; Chronic Disease; Cimetidine; Cyclic AMP; Depressive Disorder; Female; Humans; Is | 1989 |
Treatment of chronic Epstein-Barr virus disease with H2 blockers.
Topics: Cimetidine; Cognition Disorders; Depressive Disorder; Herpesviridae Infections; Herpesvirus 4, Human | 1986 |
Psychosis in association with combined cimetidine and imipramine treatment.
Topics: Adult; Cimetidine; Depressive Disorder; Drug Therapy, Combination; Female; Gastroesophageal Reflux; | 1987 |