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cimetidine and Delayed Effects, Prenatal Exposure

cimetidine has been researched along with Delayed Effects, Prenatal Exposure in 4 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Research Excerpts

ExcerptRelevanceReference
"Cimetidine, ranitidine, or water was administered to pregnant rats from the 12th day of pregnancy through weaning at 21 days of age."3.67Prenatal and neonatal exposure of male rat pups to cimetidine but not ranitidine adversely affects subsequent adult sexual functioning. ( Gavaler, JS; Parker, S; Pohl, CR; Schade, RR; Van Thiel, DH, 1984)
"Cimetidine has been shown to induce gonadal and sexual dysfunction in men."1.31Effects of the prenatal administration of cimetidine on testicular descent and genital differentiation in rats. ( Kai, H; Suita, S; Takeshi, S, 2002)
"Cimetidine was administered in the mothers' drinking water at several levels reflecting both human and rat therapeutic-like doses from day 17 of gestation through day 7 of lactation."1.27Prospective study on the sexual development of male and female rats perinatally exposed to maternally administered cimetidine. ( Babalola, GO; Bitar, MS; Hirst, SA; Shapiro, BH, 1988)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Parker, S1
Schade, RR1
Pohl, CR1
Gavaler, JS1
Van Thiel, DH1
BilynskiÄ­, BT1
Shparik, IaV1
Takeshi, S1
Kai, H1
Suita, S1
Shapiro, BH1
Hirst, SA1
Babalola, GO1
Bitar, MS1

Reviews

1 review available for cimetidine and Delayed Effects, Prenatal Exposure

ArticleYear
[Carcinogenicity of various drugs].
    Voprosy onkologii, 1984, Volume: 30, Issue:8

    Topics: Adult; Animals; Anti-Bacterial Agents; Arsenicals; Barbiturates; Brain Neoplasms; Carcinogens; Child

1984

Other Studies

3 other studies available for cimetidine and Delayed Effects, Prenatal Exposure

ArticleYear
Prenatal and neonatal exposure of male rat pups to cimetidine but not ranitidine adversely affects subsequent adult sexual functioning.
    Gastroenterology, 1984, Volume: 86, Issue:4

    Topics: Animals; Cimetidine; Evaluation Studies as Topic; Female; Gestational Age; Luteinizing Hormone; Male

1984
Effects of the prenatal administration of cimetidine on testicular descent and genital differentiation in rats.
    Surgery, 2002, Volume: 131, Issue:1 Suppl

    Topics: Age Factors; Animals; Anti-Ulcer Agents; Cimetidine; Contraindications; Cryptorchidism; Female; Inci

2002
Prospective study on the sexual development of male and female rats perinatally exposed to maternally administered cimetidine.
    Toxicology letters, 1988, Volume: 44, Issue:3

    Topics: Androgens; Animals; Body Weight; Cimetidine; Estrus; Female; Male; Orchiectomy; Organ Size; Perinato

1988