cimetidine has been researched along with Delayed Effects, Prenatal Exposure in 4 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cimetidine, ranitidine, or water was administered to pregnant rats from the 12th day of pregnancy through weaning at 21 days of age." | 3.67 | Prenatal and neonatal exposure of male rat pups to cimetidine but not ranitidine adversely affects subsequent adult sexual functioning. ( Gavaler, JS; Parker, S; Pohl, CR; Schade, RR; Van Thiel, DH, 1984) |
| "Cimetidine has been shown to induce gonadal and sexual dysfunction in men." | 1.31 | Effects of the prenatal administration of cimetidine on testicular descent and genital differentiation in rats. ( Kai, H; Suita, S; Takeshi, S, 2002) |
| "Cimetidine was administered in the mothers' drinking water at several levels reflecting both human and rat therapeutic-like doses from day 17 of gestation through day 7 of lactation." | 1.27 | Prospective study on the sexual development of male and female rats perinatally exposed to maternally administered cimetidine. ( Babalola, GO; Bitar, MS; Hirst, SA; Shapiro, BH, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Parker, S | 1 |
| Schade, RR | 1 |
| Pohl, CR | 1 |
| Gavaler, JS | 1 |
| Van Thiel, DH | 1 |
| Bilynskiĭ, BT | 1 |
| Shparik, IaV | 1 |
| Takeshi, S | 1 |
| Kai, H | 1 |
| Suita, S | 1 |
| Shapiro, BH | 1 |
| Hirst, SA | 1 |
| Babalola, GO | 1 |
| Bitar, MS | 1 |
1 review available for cimetidine and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
[Carcinogenicity of various drugs].
Topics: Adult; Animals; Anti-Bacterial Agents; Arsenicals; Barbiturates; Brain Neoplasms; Carcinogens; Child | 1984 |
3 other studies available for cimetidine and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Prenatal and neonatal exposure of male rat pups to cimetidine but not ranitidine adversely affects subsequent adult sexual functioning.
Topics: Animals; Cimetidine; Evaluation Studies as Topic; Female; Gestational Age; Luteinizing Hormone; Male | 1984 |
Effects of the prenatal administration of cimetidine on testicular descent and genital differentiation in rats.
Topics: Age Factors; Animals; Anti-Ulcer Agents; Cimetidine; Contraindications; Cryptorchidism; Female; Inci | 2002 |
Prospective study on the sexual development of male and female rats perinatally exposed to maternally administered cimetidine.
Topics: Androgens; Animals; Body Weight; Cimetidine; Estrus; Female; Male; Orchiectomy; Organ Size; Perinato | 1988 |