Page last updated: 2024-10-25

cimetidine and Cross Infection

cimetidine has been researched along with Cross Infection in 13 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Cross Infection: Any infection which a patient contracts in a health-care institution.

Research Excerpts

ExcerptRelevanceReference
"Fifty-six patients were randomized to receive cimetidine and their rate of pneumonia was 12."9.07Nosocomial pneumonia during stress ulcer prophylaxis with cimetidine and sucralfate. ( Celoria, G; Dawson, J; Navab, F; Ryan, P; Teres, D, 1993)
" infusion of cimetidine, a histamine-2 (H2) receptor antagonist, is needed to prevent upper gastrointestinal (GI) hemorrhage when compared with placebo and if that usage is associated with an increased risk of nosocomial pneumonia."9.07Continuous intravenous cimetidine decreases stress-related upper gastrointestinal hemorrhage without promoting pneumonia. ( Booth, FV; Bowman, SC; D'Ambrosio, CA; Hampsey, J; Jacobs, DM; Karlstadt, RG; Martin, LF; Rockhold, FW; Silverstein, JH, 1993)
"The observed effects of cimetidine and sucralfate on the incidence and severity of hemorrhage from stress-related gastritis were not significant when compared with no treatment."5.07Prophylaxis for stress-related gastric hemorrhage in the medical intensive care unit. A randomized, controlled, single-blind study. ( Ben-Menachem, T; Bresalier, RS; Divine, G; Fogel, R; Hadzijahic, N; Patel, RV; Touchette, M; Verter, J; Zarowitz, BJ, 1994)
"Fifty-six patients were randomized to receive cimetidine and their rate of pneumonia was 12."5.07Nosocomial pneumonia during stress ulcer prophylaxis with cimetidine and sucralfate. ( Celoria, G; Dawson, J; Navab, F; Ryan, P; Teres, D, 1993)
" infusion of cimetidine, a histamine-2 (H2) receptor antagonist, is needed to prevent upper gastrointestinal (GI) hemorrhage when compared with placebo and if that usage is associated with an increased risk of nosocomial pneumonia."5.07Continuous intravenous cimetidine decreases stress-related upper gastrointestinal hemorrhage without promoting pneumonia. ( Booth, FV; Bowman, SC; D'Ambrosio, CA; Hampsey, J; Jacobs, DM; Karlstadt, RG; Martin, LF; Rockhold, FW; Silverstein, JH, 1993)
"Critically ill trauma patients were entered in a prospective, randomized trial to determine the role of gastric colonization in the development of pneumonia."2.67Role of gastric colonization in the development of pneumonia in critically ill trauma patients: results of a prospective randomized trial. ( Burchard, KW; DeMaria, E; McDonald, L; Peterson, D; Robinson, A; Simms, HH, 1991)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19906 (46.15)18.7374
1990's7 (53.85)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
GONZALEZ, S1
ILLESCAS, A1
ESCARZAGA, E1
Hillman, KM1
Ben-Menachem, T2
Fogel, R2
Patel, RV2
Touchette, M1
Zarowitz, BJ2
Hadzijahic, N1
Divine, G1
Verter, J1
Bresalier, RS2
Ryan, P1
Dawson, J1
Teres, D1
Celoria, G1
Navab, F1
Martin, LF1
Booth, FV1
Karlstadt, RG2
Silverstein, JH1
Jacobs, DM1
Hampsey, J1
Bowman, SC1
D'Ambrosio, CA1
Rockhold, FW1
McCarthy, BD1
Schiffman, RM1
Nerenz, DR1
Kappstein, I1
Schulgen, G1
Friedrich, T1
Hellinger, P1
Benzing, A1
Geiger, K1
Daschner, FD1
Tryba, M1
Simms, HH1
DeMaria, E1
McDonald, L1
Peterson, D1
Robinson, A1
Burchard, KW1
Palmer, RH1
Donowitz, LG1
Page, MC1
Mileur, BL1
Guenthner, SH1
Craven, DE1
Kunches, LM1
Kilinsky, V1
Lichtenberg, DA1
Make, BJ1
McCabe, WR1
Ho, JL1
Shands, KN1
Friedland, G1
Eckind, P1
Fraser, DW1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Lactobacillus GG in the Prophylaxis of Ventilator Associated Pneumonia: A Prospective, Randomized, Placebo-controlled, Double-blind Study[NCT00613795]Phase 3125 participants (Anticipated)Interventional2004-08-31Completed
Comparison of Esomeprazole and Famotidine for Stress Ulcer Prophylaxis in Neurosurgical Intensive Care Unit[NCT00633035]Phase 460 participants (Actual)Interventional2007-09-30Completed
Comparison of Intravenous Pantoprazole and Famotidine for Stress Ulcer Prophylaxis in Patients After Major Abdominal Surgery[NCT00839488]Phase 46 participants (Actual)Interventional2008-04-30Terminated (stopped due to the chief of GS left the hopsital and the successor did't want to keep on this study)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for cimetidine and Cross Infection

ArticleYear
Prophylaxis for stress-related gastrointestinal hemorrhage: a cost effectiveness analysis.
    Critical care medicine, 1996, Volume: 24, Issue:2

    Topics: Anti-Ulcer Agents; Cimetidine; Cost-Benefit Analysis; Cross Infection; Decision Trees; Drug Costs; G

1996
[Acid reducing drugs for prevention of stress ulcer: cause for the development of nosocomial pneumonia? Arguments pro].
    Zeitschrift fur Gastroenterologie, 1991, Volume: 29 Suppl 1

    Topics: Anti-Ulcer Agents; Cimetidine; Colony Count, Microbial; Critical Care; Cross Infection; Gastric Acid

1991

Trials

4 trials available for cimetidine and Cross Infection

ArticleYear
Prophylaxis for stress-related gastric hemorrhage in the medical intensive care unit. A randomized, controlled, single-blind study.
    Annals of internal medicine, 1994, Oct-15, Volume: 121, Issue:8

    Topics: Adult; Aged; Blood Transfusion; Cimetidine; Critical Illness; Cross Infection; Female; Gastritis; Ga

1994
Nosocomial pneumonia during stress ulcer prophylaxis with cimetidine and sucralfate.
    Archives of surgery (Chicago, Ill. : 1960), 1993, Volume: 128, Issue:12

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Cimetidine; Cross Infection; Femal

1993
Continuous intravenous cimetidine decreases stress-related upper gastrointestinal hemorrhage without promoting pneumonia.
    Critical care medicine, 1993, Volume: 21, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cimetidine; Critical Care; Cross Infection; Double-Blind

1993
Continuous intravenous cimetidine decreases stress-related upper gastrointestinal hemorrhage without promoting pneumonia.
    Critical care medicine, 1993, Volume: 21, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cimetidine; Critical Care; Cross Infection; Double-Blind

1993
Continuous intravenous cimetidine decreases stress-related upper gastrointestinal hemorrhage without promoting pneumonia.
    Critical care medicine, 1993, Volume: 21, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cimetidine; Critical Care; Cross Infection; Double-Blind

1993
Continuous intravenous cimetidine decreases stress-related upper gastrointestinal hemorrhage without promoting pneumonia.
    Critical care medicine, 1993, Volume: 21, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cimetidine; Critical Care; Cross Infection; Double-Blind

1993
Role of gastric colonization in the development of pneumonia in critically ill trauma patients: results of a prospective randomized trial.
    The Journal of trauma, 1991, Volume: 31, Issue:4

    Topics: Adolescent; Adult; Antacids; Bacteria; Cimetidine; Cross Infection; Gastric Juice; Humans; Hydrogen-

1991

Other Studies

7 other studies available for cimetidine and Cross Infection

ArticleYear
[REDUCTION OF BACTERIAL CONTAMINATION OF THE ENVIRONMENT IN A GENERAL HOSPITAL, BY THE USE OF A NEW GERMICIDE: BIOMET 66].
    Revista medica del Hospital General, 1963, Volume: 26

    Topics: Aerosols; Air Pollution; Ammonium Compounds; Anti-Infective Agents, Local; Carrier State; Cimetidine

1963
Colonisation of the gastric contents in critically ill patients.
    Acta anaesthesiologica Belgica, 1983, Volume: 34, Issue:3

    Topics: Cimetidine; Critical Care; Cross Infection; Gastric Acidity Determination; Gastric Mucosa; Humans; S

1983
Incidence of pneumonia in mechanically ventilated patients treated with sucralfate or cimetidine as prophylaxis for stress bleeding: bacterial colonization of the stomach.
    The American journal of medicine, 1991, Aug-08, Volume: 91, Issue:2A

    Topics: Adult; Bacterial Infections; Cimetidine; Colony Count, Microbial; Cross Infection; Female; Gastric A

1991
The effect of H2 receptor antagonists on intragastric pH in critically ill patients.
    Intensive care medicine, 1989, Volume: 15, Issue:7

    Topics: Cimetidine; Critical Care; Cross Infection; Gastric Acid; Gastric Acidity Determination; Humans; Hyd

1989
Alteration of normal gastric flora in critical care patients receiving antacid and cimetidine therapy.
    Infection control : IC, 1986, Volume: 7, Issue:1

    Topics: Antacids; Bacterial Infections; Cimetidine; Critical Care; Cross Infection; Gastric Acidity Determin

1986
Risk factors for pneumonia and fatality in patients receiving continuous mechanical ventilation.
    The American review of respiratory disease, 1986, Volume: 133, Issue:5

    Topics: Adult; Aged; Cimetidine; Cross Infection; Female; Humans; Male; Massachusetts; Middle Aged; Monitori

1986
An outbreak of type 4b Listeria monocytogenes infection involving patients from eight Boston hospitals.
    Archives of internal medicine, 1986, Volume: 146, Issue:3

    Topics: Aged; Antacids; Boston; Cimetidine; Cross Infection; Disease Outbreaks; Epidemiologic Methods; Femal

1986