cimetidine has been researched along with Coronary Disease in 16 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of the H1-receptor antagonists promethazine, mepyramine, and chlorpheniramine on ischemic and reperfusion arrhythmias were studied in the isolated perfused rat heart." | 7.67 | Effects of promethazine on ischemic and reperfusion arrhythmias in rat heart. ( Bralet, J; Opie, LH; Rochette, L; Yao-Kouame, J, 1988) |
| "1 kcal) hemodynamic response (PHR), vegetative reaction and cimetidine effect were registered in 120 coronary patients with duodenal ulcer, 126 patients with duodenal ulcer and 30 healthy controls." | 3.69 | [Cardiovascular responses to feeding in patients with ischemic heart disease combined with duodenal ulcer]. ( Fisher, AA; Naurbieva, EN, 1996) |
| "The effects of ranitidine and cimetidine on ventricular fibrillation threshold and haemodynamics were studied in pentobarbitone-anaesthetized dogs subjected to acute coronary artery ligation." | 3.67 | Cardiovascular effects of ranitidine and cimetidine during acute myocardial ischaemia in anaesthetized dogs. ( Dai, S, 1986) |
| "The effects of the H1-receptor antagonists promethazine, mepyramine, and chlorpheniramine on ischemic and reperfusion arrhythmias were studied in the isolated perfused rat heart." | 3.67 | Effects of promethazine on ischemic and reperfusion arrhythmias in rat heart. ( Bralet, J; Opie, LH; Rochette, L; Yao-Kouame, J, 1988) |
| "Cimetidine treatment results in redistribution of HDL subfractions in favour of HDL2." | 2.66 | The effect of cimetidine and ranitidine on serum high density lipoprotein subfractions. ( Champion, MC; Ooi, TC; Peden, NR; Simo, EI, 1985) |
| "There was no evidence of causes for the anaphylactic reactions over a two and a half year period." | 1.27 | Life-threatening idiopathic anaphylaxis associated with hyperimmunoglobulinemia E. ( Greenberger, PA, 1984) |
| "Dimaprit was able to decrease the number of ventricular extrasystoles and to modulate plasma histamine levels." | 1.27 | Histamine release during an experimental coronary thrombosis in awake dog. ( Gagnol, JP; Gautier, P; Masini, E; Pezziardi, F; Phanchenault, J, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (93.75) | 18.7374 |
| 1990's | 1 (6.25) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Greenberger, PA | 1 |
| Saga, T | 1 |
| Iemura, J | 1 |
| Noritake, S | 1 |
| Oku, H | 1 |
| Kawai, A | 1 |
| Martin, J | 1 |
| Cano, N | 1 |
| Di Costanzo, J | 1 |
| Richieri, JP | 1 |
| Salomon, M | 1 |
| Deveze, JL | 1 |
| Courbier, R | 1 |
| Nikolic, G | 1 |
| Singh, JB | 1 |
| Baumann, G | 1 |
| Loher, U | 1 |
| Felix, SB | 1 |
| Heidecke, CD | 1 |
| Riess, G | 1 |
| Ludwig, L | 1 |
| Blömer, H | 1 |
| Bragotti, R | 1 |
| Binaghi, F | 1 |
| Figus, A | 1 |
| Lippi, M | 1 |
| Fisher, AA | 1 |
| Naurbieva, EN | 1 |
| Masini, E | 1 |
| Phanchenault, J | 1 |
| Pezziardi, F | 1 |
| Gautier, P | 1 |
| Gagnol, JP | 1 |
| Kharlamova, IV | 1 |
| Sivkov, II | 1 |
| Starodubtsev, AK | 1 |
| Bogovskiĭ, BP | 1 |
| Blinkov, IL | 1 |
| Rubin, MP | 1 |
| Dai, S | 1 |
| Fears, R | 1 |
| Rochette, L | 1 |
| Yao-Kouame, J | 1 |
| Bralet, J | 1 |
| Opie, LH | 1 |
| Vigorito, C | 1 |
| Poto, S | 1 |
| Picotti, GB | 1 |
| Triggiani, M | 1 |
| Marone, G | 1 |
| Ooi, TC | 1 |
| Peden, NR | 1 |
| Champion, MC | 1 |
| Simo, EI | 1 |
| Tomoike, H | 1 |
| Tozzi, CA | 1 |
| Dorrell, SG | 1 |
| Merrill, GF | 1 |
1 review available for cimetidine and Coronary Disease
| Article | Year |
|---|---|
Mode of action of lipid-lowering drugs.
Topics: Adrenergic beta-Antagonists; Bile Acids and Salts; Cimetidine; Coronary Disease; Enzyme Induction; H | 1987 |
1 trial available for cimetidine and Coronary Disease
| Article | Year |
|---|---|
The effect of cimetidine and ranitidine on serum high density lipoprotein subfractions.
Topics: Adult; Cholesterol; Cholesterol, HDL; Cimetidine; Clinical Trials as Topic; Coronary Disease; Humans | 1985 |
14 other studies available for cimetidine and Coronary Disease
| Article | Year |
|---|---|
Life-threatening idiopathic anaphylaxis associated with hyperimmunoglobulinemia E.
Topics: Anaphylaxis; Cimetidine; Coronary Disease; Diphenhydramine; Humans; Hydroxyzine; Hypergammaglobuline | 1984 |
[Stress ulcer after open heart surgery].
Topics: Cardiac Surgical Procedures; Cimetidine; Coronary Disease; Duodenal Ulcer; Electrocoagulation; Human | 1983 |
[Prevention of gastroduodenal complications in coronary surgery. Usefulness of preoperative fiberoscopy].
Topics: Antacids; Cimetidine; Coronary Artery Bypass; Coronary Disease; Duodenal Diseases; Endoscopy; Female | 1982 |
Cimetidine, vasopressin and chronotropic incompetence.
Topics: Arrhythmias, Cardiac; Bradycardia; Cimetidine; Coronary Disease; Drug Therapy, Combination; Electroc | 1982 |
Deleterious effects of cimetidine in the presence of histamine on coronary circulation. Possible clinical implications in anaphylactic states in individuals with coronary heart disease.
Topics: Anaphylaxis; Animals; Cimetidine; Coronary Circulation; Coronary Disease; Drug Interactions; Female; | 1982 |
[Pharmacological interference between cimetidine and digoxin].
Topics: Cimetidine; Coronary Disease; Digoxin; Drug Interactions; Gastric Acid; Guanidines; Humans | 1981 |
[Cardiovascular responses to feeding in patients with ischemic heart disease combined with duodenal ulcer].
Topics: Cimetidine; Coronary Disease; Duodenal Ulcer; Female; Food; Heart Function Tests; Histamine H2 Antag | 1996 |
Histamine release during an experimental coronary thrombosis in awake dog.
Topics: Animals; Cimetidine; Coronary Disease; Dimaprit; Dogs; Feedback; Female; Histamine Release; Male; Th | 1985 |
[Treatment of arrhythmia in patients with chronic ischemic heart disease using kinilentin combined with an inhibitor or inductor of microsomal oxidation].
Topics: Arrhythmias, Cardiac; Benzhydryl Compounds; Cimetidine; Coronary Disease; Drug Therapy, Combination; | 1989 |
Cardiovascular effects of ranitidine and cimetidine during acute myocardial ischaemia in anaesthetized dogs.
Topics: Animals; Cimetidine; Coronary Disease; Dogs; Female; Hemodynamics; Histamine; Histamine H2 Antagonis | 1986 |
Effects of promethazine on ischemic and reperfusion arrhythmias in rat heart.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chlorpheniramine; Cimetidine; Coronary Diseas | 1988 |
Effect of activation of the H1 receptor on coronary hemodynamics in man.
Topics: Adult; Angina Pectoris; Cimetidine; Coronary Disease; Coronary Vasospasm; Coronary Vessels; Female; | 1986 |
Animal models of coronary spasm and the pathophysiological events in regional vascular hypercontraction.
Topics: Animals; Cimetidine; Coronary Angiography; Coronary Circulation; Coronary Disease; Coronary Vasospas | 1985 |
Evidence of histamine-induced myocardial ischaemia: reversal by chlorpheniramine and potentiation by atherosclerosis.
Topics: Animals; Arteriosclerosis; Chlorpheniramine; Cimetidine; Coronary Circulation; Coronary Disease; Cor | 1985 |