cimetidine has been researched along with Chronic Kidney Diseases in 3 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cimetidine is a potent organic cation transporter 2/multidrug and toxin extrusion protein inhibitor." | 1.56 | A Comprehensive Whole-Body Physiologically Based Pharmacokinetic Drug-Drug-Gene Interaction Model of Metformin and Cimetidine in Healthy Adults and Renally Impaired Individuals. ( Ebner, T; Hanke, N; Ishiguro, N; Lehr, T; Müller, F; Nock, V; Selzer, D; Stopfer, P; Türk, D; Wiebe, S, 2020) |
| " The aim of this study was to assess whether appropriate dosage adjustments were made in hospitalized patients with renal impairment." | 1.42 | Drug dosage adjustment in hospitalized patients with renal impairment at Tikur Anbessa specialized hospital, Addis Ababa, Ethiopia. ( Getachew, H; Shibeshi, W; Tadesse, Y, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Hanke, N | 1 |
| Türk, D | 1 |
| Selzer, D | 1 |
| Ishiguro, N | 1 |
| Ebner, T | 1 |
| Wiebe, S | 1 |
| Müller, F | 1 |
| Stopfer, P | 1 |
| Nock, V | 1 |
| Lehr, T | 1 |
| Getachew, H | 1 |
| Tadesse, Y | 1 |
| Shibeshi, W | 1 |
| Musso, CG | 1 |
| Michelángelo, H | 1 |
| Vilas, M | 1 |
| Martinez, B | 1 |
| Bonetto, A | 1 |
| Jauregui, R | 1 |
| Algranati, L | 1 |
3 other studies available for cimetidine and Chronic Kidney Diseases
| Article | Year |
|---|---|
A Comprehensive Whole-Body Physiologically Based Pharmacokinetic Drug-Drug-Gene Interaction Model of Metformin and Cimetidine in Healthy Adults and Renally Impaired Individuals.
Topics: Adult; Cimetidine; Drug Interactions; Humans; Hypoglycemic Agents; Metformin; Pharmacogenetics; Rena | 2020 |
Drug dosage adjustment in hospitalized patients with renal impairment at Tikur Anbessa specialized hospital, Addis Ababa, Ethiopia.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Allopurinol; Anti-Arrhythmia Agents | 2015 |
Renal creatinine handling in very old patients with chronic renal disease.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Cimetidine; Creatinine; Female; Glomerular Filtration R | 2011 |