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cimetidine and Chronic Illness

cimetidine has been researched along with Chronic Illness in 120 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Research Excerpts

ExcerptRelevanceReference
"In a randomized, double-blind, parallel-group study in 16 patients with chronic urticaria, we investigated the pharmacokinetics and suppressive effect on the histamine-induced wheal and flare of a single dose of hydroxyzine 25 mg or cetirizine 10 mg, given before and after treatment with cimetidine 600 mg every 12 hours for 10 days."9.08Effect of the H2-antagonist cimetidine on the pharmacokinetics and pharmacodynamics of the H1-antagonists hydroxyzine and cetirizine in patients with chronic urticaria. ( Simons, FE; Simons, KJ; Sussman, GL, 1995)
"To assess the effect of the H2-antagonist cimetidine in the treatment of patients with interstitial cystitis (IC) refractory to other conservative therapies."9.07Cimetidine in the treatment of interstitial cystitis. ( Emerson, L; Morales, A; Seshadri, P, 1994)
"Twelve patients with stable congestive heart failure and left ventricular dysfunction were enrolled in a double-blind, randomized crossover trial of famotidine, cimetidine and placebo to determine whether histamine type 2 (H2) antagonists adversely affect left ventricular systolic performance."9.07Effects of histamine type 2-receptor antagonists cimetidine and famotidine on left ventricular systolic function in chronic congestive heart failure. ( Jarboe, LA; Lee, RT; Solomon, SD; Wolfe, MM; Wolff, S, 1993)
"We randomly assigned 159 patients with non-ulcer dyspepsia, defined as chronic or recurrent epigastric pain without concomitant symptoms of the irritable bowel syndrome and with no evidence of organic disease, to treatment for three weeks with an antacid suspension one and three hours after meals, 400 mg of cimetidine twice a day, or placebo, according to a double-blind, double-dummy model."9.06Absence of therapeutic benefit from antacids or cimetidine in non-ulcer dyspepsia. ( Adami, HO; Bates, S; Bergström, R; Gustavsson, S; Lööf, L; Nyberg, A; Nyrén, O, 1986)
"We compared ranitidine and cimetidine in maintenance therapy to prevent duodenal ulcer recurrence over a period of 24 months."9.06Prevention of duodenal ulcer occurrence. Double-blind comparison of ranitidine and cimetidine. ( Billington, B; Bolin, TD; Davis, AE, 1987)
"We studied the effect of cimetidine maintenance therapy on the socioeconomic life of patients with gastric ulcers in the year after healing and the extent to which treatment was cost-effective."9.06The effect of maintenance cimetidine therapy on the medical, social and economic aspects of patients with chronic gastric ulcers. A placebo-controlled prospective study. ( Byth, K; Gellatly, R; Piper, DW; Pym, BM; Seville, P; Toy, S, 1986)
"The efficacy of a 4-week cimetidine treatment was examined by a double-blind randomized study in 37 outpatients with endoscopically verified chronic gastric ulcer."9.06Cimetidine and placebo-cimetidine in the treatment of patients with chronic gastric ulcer (a multiclinical randomized double-blind comparative study). ( Deák, G; Mózsik, G; Patty, I; Tárnok, F, 1988)
"The course of gastritis and Campylobacter pylori was studied in a single-blind randomized trial comparing cimetidine 200 mg three times a day and 400 mg at night and sucralfate 1 g four times a day orally for four weeks in 140 patients with proved duodenal ulcer."9.06Effect of sucralfate and cimetidine on duodenal ulcer-associated antral gastritis and Campylobacter pylori. ( Branicki, FJ; Fok, J; Ho, J; Hui, WM; Lai, CL; Lam, SK; Lau, WY; Lok, AS; Ng, I; Ng, MM, 1989)
"Sixty patients with chronic gastric ulcer (UGC) received randomly cimetidine (CMT) or ranitidine (RNT) for 2 years, at a dose of 400 mg/night CMT or 150 mg/night RNT, in a prospective, controlled, simple blind clinical trial of these medications and endoscopy findings."9.06[Ranitidine and cimetidine in long-term (2 years) maintenance therapy of chronic gastric ulcer]. ( Varas, MJ, 1989)
"Thirty-seven patients with chronic duodenal ulceration were entered into an endoscopically controlled trial of cimetidine (Tagamet) versus tri-potassium di-citrato bismuthate (De-Nol)."9.05Double-blind trial of cimetidine versus tri-potassium di-citrato bismuthate in chronic duodenal ulceration. ( Cowen, A; Pollard, EJ; Ward, M, 1981)
"Forty patients with endoscopically proven persistent duodenal ulcer who had been treated for six weeks with cimetidine (1 g/day) were randomly allocated to receive a further six weeks' treatment with cimetidine (1 g/day) or ranitidine (300 mg/day)."9.05Treatment of 'cimetidine-resistant' chronic duodenal ulcers with ranitidine or cimetidine: a randomised multicentre study. ( Basilisco, G; Bianchi, PA; Quatrini, M, 1984)
"The aim of the study was to compare the effectiveness of ranitidine and cimetidine in accelerating the healing of chronic gastric ulcer."9.05Comparison of ranitidine and cimetidine in the treatment of chronic gastric ulcer. A double-blind trial. ( Barr, GD; Cowen, AE; Kellow, JE; Piper, DW; Ward, M; Wood, L, 1983)
"Forty-eight patients with chronic duodenal ulcers which were healed with cimetidine were allocated at random into two equal groups to assess different ways of using cimetidine during one year of treatment."9.05Long-term treatment of duodenal ulcer with cimetidine. Intermittent or continuous therapy? ( Hecker, R; Hetzel, DJ; Shearman, DJ, 1980)
"Recurrence rates of chronic duodenal ulcer after initial therapy with pirenzepine or cimetidine were investigated in a prospective, randomized trial with a total of 80 patients."9.05[Recurrence of chronic duodenal ulcer following initial therapy with pirenzepine or cimetidine]. ( Dufek, W; Hentschel, E; Schütze, K, 1985)
"The new H2 receptor antagonist, famotidine, has been tested in open and double-blind studies in over 2,000 acute duodenal or gastric ulcer patients as well as in the maintenance of chronic duodenal ulcer patients."9.05Famotidine in the treatment of gastric and duodenal ulceration: overview of clinical experience. ( Bianchi Porro, G, 1985)
"68 patients with chronic peptic ulcer took part in a double-blind trial in which 32 received the histamine H2-receptor antagonist cimetidine, (400 mg twice daily) and 36 received a placebo, for a year."9.04Maintenance treatment of recurrent peptic ulcer by cimetidine. ( Bodemar, G; Walan, A, 1978)
"The effect of cimetidine in the daily dose of 1200 mg on the healing rate of chronic gastric ulcer was assessed in a randomized double-blind trial in 48 patients."9.04Cimetidine and gastric ulcer healing: a double-blind controlled trial. ( Crawford, J; Gillespie, P; Hunt, JH; Landecker, KD; Piper, DW, 1979)
"Patients suffering from chronic duodenal ulceration were allocated at random to treatment with either cimetidine (400 mg twice daily) or matching placebo for six months."9.04Double-blind comparison of cimetidine and placebo in the maintenance of healing of chronic duodenal ulceration. ( Bardhan, KD; Duthie, HL; Edwards, JL; Fussey, IV; Haggie, SJ; Saul, DM; Smith, PM; Wyllie, JH, 1979)
"Sixty patients with benign chronic gastric ulcer were treated in a controlled clinical trial to assess the relative efficacy of cimetidine and tri-potassium di-citrato bismuthate (De-Nol)."9.04Efficacy of cimetidine and tri-potassium di-citrato bismuthate (De-Nol) in chronic gastric ulceration: a comparative study. ( Cowen, AE; Cowlishaw, JL; Tanner, AR; Ward, M, 1979)
"This study examined the relationship between healing of acetic acid-induced chronic gastric ulcer and connexin formation."7.69Relationship between healing of acetic acid-induced chronic gastric ulcer and connexin. ( Fujita, T; Kushima, R; Mine, T, 1997)
"The results of patients with chronic erosive gastritis treated with sucralfate (Venter) and cimetidine (Altramet) were compared."7.69[Comparative evaluation of sucralfate (Venter) and cimetidine (Altramet) efficiency in treatment of chronic erosive gastritis]. ( Kula, Z; Rudziński, J; Walasek, L, 1994)
"Capsaicin promotes the healing of acetic acid induced gastric ulcer, probably by its gastric hyperaemic effect."7.69Effect of capsaicin and cimetidine on the healing of acetic acid induced gastric ulceration in the rat. ( Chen, FC; Kang, JY; Teng, CH, 1996)
"Penetrated cysteamine-induced duodenal ulcers in rats have a very prolonged course of healing."7.67Effect of antisecretory agents and vagotomy on healing of "chronic" cysteamine-induced duodenal ulcers in rats. ( Kirkegaard, P; Poulsen, SS; Raaberg, L; Skov Olsen, P; Therkelsen, K, 1986)
"The effects of cimetidine on healing of gastric and duodenal ulcers induced in mongrel dogs were studied."7.66Effects of cimetidine on healing of chronic gastric and duodenal ulcers in dogs. ( Murata, T; Okabe, S; Takeuchi, K; Urushidani, T, 1978)
"Thirteen patients with Zollinger-Ellison syndrome (ZES) were treated with cimetidine."7.66Cimetidine treatment of acute and chronic Zollinger-Ellison syndrome. ( Bonfils, S; Gratton, J; Mignon, M, 1979)
"The authors have studied the effects of cimetidine on the healing of chronic gastric ulcers induced in rats."7.66Effect of cimetidine on chronic gastric ulcers produced experimentally in rats. ( Kilam, SK; MacPherson, BR, 1979)
"Quantitative ultrastructural analyses of the parietal cells have been performed on eleven patients with chronic duodenal ulcer, before and after 8 weeks' treatment with a histamine H2-receptor antagonist (cimetidine, 1 g/day)."7.66The parietal cells in duodenal ulcer patients. A quantitative ultrastructural study before and during treatment with cimetidine. ( Christiansen, LA; Madsen, PE; Nielsen, H, 1980)
"Cimetidine was cost-effective in both gastric ulcer and duodenal ulcer patients in the first 2 years after healing."6.67Cost-effectiveness of cimetidine maintenance therapy in chronic gastric and duodenal ulcer. ( Byth, K; Middleton, WR; Piper, DW; Pym, B; Sandstad, J; Seville, P; Talley, NJ, 1990)
"When lafutidine (3, 10 mg/kg) was administered orally once daily for one week after the withdrawal of ammonia or TCA solution, the recovery of the mucosal thickness in the fundic gland area and the parietal cell number were significantly accelerated, and the recovery of mucosal thickness in the pyloric gland area also tended to be accelerated."5.30[Effect of a novel antiulcer drug, lafutidine, on experimental chronic gastritis in rats]. ( Inaba, N; Onodera, S; Shibata, M; Suzuki, T; Tanaka, M; Yamaura, T, 1997)
"Histamine was tested during hypoxic vasoconstriction."5.29Histamine induced pulmonary vasodilatation in the rat: site of action and changes in chronic hypoxia. ( Barer, GR; Howard, P; Russell, PC; Wright, CE, 1994)
"The influence of KU-1257 on the recurrence and relapse of acetic acid ulcers in rats was investigated grossly and histologically in comparison with that of cimetidine."5.29[Influence of KU-1257 on the recurrence and relapse of acetic acid-induced chronic gastric ulcers in rats]. ( Kobayashi, F; Ohkubo, H; Ohsawa, A; Sekiguchi, H; Taga, F, 1996)
"In a randomized, double-blind, parallel-group study in 16 patients with chronic urticaria, we investigated the pharmacokinetics and suppressive effect on the histamine-induced wheal and flare of a single dose of hydroxyzine 25 mg or cetirizine 10 mg, given before and after treatment with cimetidine 600 mg every 12 hours for 10 days."5.08Effect of the H2-antagonist cimetidine on the pharmacokinetics and pharmacodynamics of the H1-antagonists hydroxyzine and cetirizine in patients with chronic urticaria. ( Simons, FE; Simons, KJ; Sussman, GL, 1995)
"Twelve patients with stable congestive heart failure and left ventricular dysfunction were enrolled in a double-blind, randomized crossover trial of famotidine, cimetidine and placebo to determine whether histamine type 2 (H2) antagonists adversely affect left ventricular systolic performance."5.07Effects of histamine type 2-receptor antagonists cimetidine and famotidine on left ventricular systolic function in chronic congestive heart failure. ( Jarboe, LA; Lee, RT; Solomon, SD; Wolfe, MM; Wolff, S, 1993)
"To assess the effect of the H2-antagonist cimetidine in the treatment of patients with interstitial cystitis (IC) refractory to other conservative therapies."5.07Cimetidine in the treatment of interstitial cystitis. ( Emerson, L; Morales, A; Seshadri, P, 1994)
"Sixty patients with chronic gastric ulcer (UGC) received randomly cimetidine (CMT) or ranitidine (RNT) for 2 years, at a dose of 400 mg/night CMT or 150 mg/night RNT, in a prospective, controlled, simple blind clinical trial of these medications and endoscopy findings."5.06[Ranitidine and cimetidine in long-term (2 years) maintenance therapy of chronic gastric ulcer]. ( Varas, MJ, 1989)
"The course of gastritis and Campylobacter pylori was studied in a single-blind randomized trial comparing cimetidine 200 mg three times a day and 400 mg at night and sucralfate 1 g four times a day orally for four weeks in 140 patients with proved duodenal ulcer."5.06Effect of sucralfate and cimetidine on duodenal ulcer-associated antral gastritis and Campylobacter pylori. ( Branicki, FJ; Fok, J; Ho, J; Hui, WM; Lai, CL; Lam, SK; Lau, WY; Lok, AS; Ng, I; Ng, MM, 1989)
"The efficacy of a 4-week cimetidine treatment was examined by a double-blind randomized study in 37 outpatients with endoscopically verified chronic gastric ulcer."5.06Cimetidine and placebo-cimetidine in the treatment of patients with chronic gastric ulcer (a multiclinical randomized double-blind comparative study). ( Deák, G; Mózsik, G; Patty, I; Tárnok, F, 1988)
"We studied the effect of cimetidine maintenance therapy on the socioeconomic life of patients with gastric ulcers in the year after healing and the extent to which treatment was cost-effective."5.06The effect of maintenance cimetidine therapy on the medical, social and economic aspects of patients with chronic gastric ulcers. A placebo-controlled prospective study. ( Byth, K; Gellatly, R; Piper, DW; Pym, BM; Seville, P; Toy, S, 1986)
"We compared ranitidine and cimetidine in maintenance therapy to prevent duodenal ulcer recurrence over a period of 24 months."5.06Prevention of duodenal ulcer occurrence. Double-blind comparison of ranitidine and cimetidine. ( Billington, B; Bolin, TD; Davis, AE, 1987)
"We randomly assigned 159 patients with non-ulcer dyspepsia, defined as chronic or recurrent epigastric pain without concomitant symptoms of the irritable bowel syndrome and with no evidence of organic disease, to treatment for three weeks with an antacid suspension one and three hours after meals, 400 mg of cimetidine twice a day, or placebo, according to a double-blind, double-dummy model."5.06Absence of therapeutic benefit from antacids or cimetidine in non-ulcer dyspepsia. ( Adami, HO; Bates, S; Bergström, R; Gustavsson, S; Lööf, L; Nyberg, A; Nyrén, O, 1986)
" In this controlled randomized study, 8 hospitalized patients with severe exocrine pancreatic insufficiency and considerable steatorrhoea (greater than 15 g faecal fat/day) were treated with a conventional pancreatic enzyme preparation (Pankreon 700; 3 X 3 dragees daily), with (300 mg) and without cimetidine before meals, and with a new pH-sensitive enzyme preparation (Kreon; 3 X 6 capsules daily) comprising acid-protected granules."5.06Therapy of pancreatogenic steatorrhoea: does acid protection of pancreatic enzymes offer any advantage? ( Creutzfeldt, W; Göke, B; Lankisch, PG; Lembcke, B, 1986)
"Forty patients with endoscopically proven persistent duodenal ulcer who had been treated for six weeks with cimetidine (1 g/day) were randomly allocated to receive a further six weeks' treatment with cimetidine (1 g/day) or ranitidine (300 mg/day)."5.05Treatment of 'cimetidine-resistant' chronic duodenal ulcers with ranitidine or cimetidine: a randomised multicentre study. ( Basilisco, G; Bianchi, PA; Quatrini, M, 1984)
"The aim of the study was to compare the effectiveness of ranitidine and cimetidine in accelerating the healing of chronic gastric ulcer."5.05Comparison of ranitidine and cimetidine in the treatment of chronic gastric ulcer. A double-blind trial. ( Barr, GD; Cowen, AE; Kellow, JE; Piper, DW; Ward, M; Wood, L, 1983)
"Forty-eight patients with chronic duodenal ulcers which were healed with cimetidine were allocated at random into two equal groups to assess different ways of using cimetidine during one year of treatment."5.05Long-term treatment of duodenal ulcer with cimetidine. Intermittent or continuous therapy? ( Hecker, R; Hetzel, DJ; Shearman, DJ, 1980)
"Thirty-seven patients with chronic duodenal ulceration were entered into an endoscopically controlled trial of cimetidine (Tagamet) versus tri-potassium di-citrato bismuthate (De-Nol)."5.05Double-blind trial of cimetidine versus tri-potassium di-citrato bismuthate in chronic duodenal ulceration. ( Cowen, A; Pollard, EJ; Ward, M, 1981)
"The new H2 receptor antagonist, famotidine, has been tested in open and double-blind studies in over 2,000 acute duodenal or gastric ulcer patients as well as in the maintenance of chronic duodenal ulcer patients."5.05Famotidine in the treatment of gastric and duodenal ulceration: overview of clinical experience. ( Bianchi Porro, G, 1985)
"Recurrence rates of chronic duodenal ulcer after initial therapy with pirenzepine or cimetidine were investigated in a prospective, randomized trial with a total of 80 patients."5.05[Recurrence of chronic duodenal ulcer following initial therapy with pirenzepine or cimetidine]. ( Dufek, W; Hentschel, E; Schütze, K, 1985)
"Patients suffering from chronic duodenal ulceration were allocated at random to treatment with either cimetidine (400 mg twice daily) or matching placebo for six months."5.04Double-blind comparison of cimetidine and placebo in the maintenance of healing of chronic duodenal ulceration. ( Bardhan, KD; Duthie, HL; Edwards, JL; Fussey, IV; Haggie, SJ; Saul, DM; Smith, PM; Wyllie, JH, 1979)
"68 patients with chronic peptic ulcer took part in a double-blind trial in which 32 received the histamine H2-receptor antagonist cimetidine, (400 mg twice daily) and 36 received a placebo, for a year."5.04Maintenance treatment of recurrent peptic ulcer by cimetidine. ( Bodemar, G; Walan, A, 1978)
"Sixty patients with benign chronic gastric ulcer were treated in a controlled clinical trial to assess the relative efficacy of cimetidine and tri-potassium di-citrato bismuthate (De-Nol)."5.04Efficacy of cimetidine and tri-potassium di-citrato bismuthate (De-Nol) in chronic gastric ulceration: a comparative study. ( Cowen, AE; Cowlishaw, JL; Tanner, AR; Ward, M, 1979)
"The effect of cimetidine in the daily dose of 1200 mg on the healing rate of chronic gastric ulcer was assessed in a randomized double-blind trial in 48 patients."5.04Cimetidine and gastric ulcer healing: a double-blind controlled trial. ( Crawford, J; Gillespie, P; Hunt, JH; Landecker, KD; Piper, DW, 1979)
"We investigated the effect of probucol, a lipid-lowering agent with antioxidant properties, on HCl plus ethanol-induced gastric mucosal injury and on the healing of acetic acid-induced gastric ulcers in rats."3.70Anti-ulcer effects of antioxidants: effect of probucol. ( Ishihara, M; Ito, M; Suzuki, Y, 1998)
"We investigated the effects of cimetidine, omeprazole and atropine, antisecretory anti-ulcer agents, on the healing of gastric and duodenal ulcers simultaneously induced in the same rats."3.69Simultaneous evaluation of gastric and duodenal ulcers-healing activities of anti-ulcer agents in rats. ( Ito, M; Segami, T; Suzuki, Y, 1996)
"This study examined the relationship between healing of acetic acid-induced chronic gastric ulcer and connexin formation."3.69Relationship between healing of acetic acid-induced chronic gastric ulcer and connexin. ( Fujita, T; Kushima, R; Mine, T, 1997)
"Capsaicin promotes the healing of acetic acid induced gastric ulcer, probably by its gastric hyperaemic effect."3.69Effect of capsaicin and cimetidine on the healing of acetic acid induced gastric ulceration in the rat. ( Chen, FC; Kang, JY; Teng, CH, 1996)
"The results of patients with chronic erosive gastritis treated with sucralfate (Venter) and cimetidine (Altramet) were compared."3.69[Comparative evaluation of sucralfate (Venter) and cimetidine (Altramet) efficiency in treatment of chronic erosive gastritis]. ( Kula, Z; Rudziński, J; Walasek, L, 1994)
"The combination of hydroxyzine and cimetidine is reported to be more effective than hydroxyzine alone in chronic urticaria."3.67Cimetidine increases the plasma concentration of hydroxyzine. ( Kauppinen, K; Männistö, PT; Salo, OP, 1986)
"The cyclic adenosine monophosphate (cAMP) responses to histamine, prostaglandin-E1, and isoproterenol in polymorphonuclear leukocytes from drug-free normal controls and patients with schizophrenia or major depressive disorder were compared."3.67Cyclic-AMP production by polymorphonuclear leukocytes in psychiatric disorders. ( Coccaro, EF; Davidson, M; Davis, KL; Johns, CA; Kanof, PD; Siever, LJ, 1989)
"Gastric acid secretion in response to a protein meal and to exogenously administered synthetic human gastrin 17-I was measured in patients with Barrett's esophagus, patients with uncomplicated gastroesophageal reflux, and normal age- and sex-matched controls."3.67Elevated gastric acid secretion in patients with Barrett's metaplastic epithelium. ( Levine, DS; Mulholland, MW; Reid, BJ; Rubin, CE, 1989)
"Fifty-seven patients, with chronic duodenal ulceration resistant to cimetidine therapy, underwent proximal gastric vagotomy during the period August 1979 to May 1984."3.67Proximal gastric vagotomy in patients resistant to cimetidine. ( Temple, JG; Weaver, RM, 1985)
"The effect of extirpation of the submandibular glands, an exocrine organ for epidermal growth factor/urogastrone (EGF/URO), and the effect of oral administration of synthetic human (EGF/URO) on healing of chronic gastric ulcers in rats has been investigated."3.67Effect of sialoadenectomy and synthetic human urogastrone on healing of chronic gastric ulcers in rats. ( Nexø, E; Olsen, PS; Poulsen, SS; Therkelsen, K, 1986)
"Penetrated cysteamine-induced duodenal ulcers in rats have a very prolonged course of healing."3.67Effect of antisecretory agents and vagotomy on healing of "chronic" cysteamine-induced duodenal ulcers in rats. ( Kirkegaard, P; Poulsen, SS; Raaberg, L; Skov Olsen, P; Therkelsen, K, 1986)
"The authors have studied the effects of cimetidine on the healing of chronic gastric ulcers induced in rats."3.66Effect of cimetidine on chronic gastric ulcers produced experimentally in rats. ( Kilam, SK; MacPherson, BR, 1979)
"Thirteen patients with Zollinger-Ellison syndrome (ZES) were treated with cimetidine."3.66Cimetidine treatment of acute and chronic Zollinger-Ellison syndrome. ( Bonfils, S; Gratton, J; Mignon, M, 1979)
"Combined H1 (cyproheptadine) and H2 antihistamines (cimetidine) were tried in eight patients with chronic urticaria who were previously unresponsive to conventional anti-urticarial regimens, including type I antihistamines, hydroxyzine, ephedrine and corticosteroids."3.66Treatment of chronic idiopathic urticaria with combined H1 and H2 blockers. ( Kohler, PF; Phanuphak, P; Schocket, A, 1978)
"The effects of cimetidine on healing of gastric and duodenal ulcers induced in mongrel dogs were studied."3.66Effects of cimetidine on healing of chronic gastric and duodenal ulcers in dogs. ( Murata, T; Okabe, S; Takeuchi, K; Urushidani, T, 1978)
"Quantitative ultrastructural analyses of the parietal cells have been performed on eleven patients with chronic duodenal ulcer, before and after 8 weeks' treatment with a histamine H2-receptor antagonist (cimetidine, 1 g/day)."3.66The parietal cells in duodenal ulcer patients. A quantitative ultrastructural study before and during treatment with cimetidine. ( Christiansen, LA; Madsen, PE; Nielsen, H, 1980)
"Cimetidine was cost-effective in both gastric ulcer and duodenal ulcer patients in the first 2 years after healing."2.67Cost-effectiveness of cimetidine maintenance therapy in chronic gastric and duodenal ulcer. ( Byth, K; Middleton, WR; Piper, DW; Pym, B; Sandstad, J; Seville, P; Talley, NJ, 1990)
"Chronic urticaria is a frustrating problem for the patient and the physician."2.65Combined H1 and H2 antihistamine therapy in chronic urticaria. ( Cohen, SH; Kalbfleisch, J; Monroe, EW; Schulz, CI, 1981)
"Therapeutic measures for acute pancreatitis depend on the severity of the disease and its complications."2.37Acute and chronic pancreatitis. An update on management. ( Lankisch, PG, 1984)
"When lafutidine (3, 10 mg/kg) was administered orally once daily for one week after the withdrawal of ammonia or TCA solution, the recovery of the mucosal thickness in the fundic gland area and the parietal cell number were significantly accelerated, and the recovery of mucosal thickness in the pyloric gland area also tended to be accelerated."1.30[Effect of a novel antiulcer drug, lafutidine, on experimental chronic gastritis in rats]. ( Inaba, N; Onodera, S; Shibata, M; Suzuki, T; Tanaka, M; Yamaura, T, 1997)
"The influence of KU-1257 on the recurrence and relapse of acetic acid ulcers in rats was investigated grossly and histologically in comparison with that of cimetidine."1.29[Influence of KU-1257 on the recurrence and relapse of acetic acid-induced chronic gastric ulcers in rats]. ( Kobayashi, F; Ohkubo, H; Ohsawa, A; Sekiguchi, H; Taga, F, 1996)
"Histamine was tested during hypoxic vasoconstriction."1.29Histamine induced pulmonary vasodilatation in the rat: site of action and changes in chronic hypoxia. ( Barer, GR; Howard, P; Russell, PC; Wright, CE, 1994)
"Although gastro-esophageal reflux (GER) is one of the major causes of chronic persistent cough (CPC) in the USA and in Europe, it is a rare cause of CPC in Japan."1.29[A case of chronic persistent cough caused by gastro-esophageal reflux]. ( Amemiya, T; Fujimura, M; Matsuda, T; Mizuguchi, M; Nishi, K; Ooka, T, 1995)
"Chronic duodenal ulcer is diagnosed more frequently in children since recent advances in panendoscopy techniques."1.28Chronic duodenal ulcer in children: clinical observation and response to treatment. ( Chang, MH; Chiang, BL; Hsu, JY; Lin, MI; Wang, CY; Wang, TH, 1989)
" The authors report increased serum clozapine levels and adverse side effects during clozapine and cimetidine treatment but not during clozapine and ranitidine treatment in a patient with chronic paranoid schizophrenia."1.28A case report of cimetidine-induced clozapine toxicity. ( Cooper, T; Lieberman, JA; Masiar, S; Picou, D; Szymanski, S, 1991)
"Pretreatment with Cimetidine did not increase the enzyme concentrations further."1.27Exocrine pancreatic substitution: facts and controversies. ( Worning, H, 1986)
" However, the patients' compliance is just as important; the dosage must be individualized."1.27Enzyme substitution in pancreatic disease. ( Andrén-Sandberg, A, 1987)
"Cimetidine clearance was affected little by age."1.26Age, disease, and cimetidine disposition in healthy subjects and chronically ill patients. ( Bernhard, H; Calleri, GM; Cerra, FB; French, MA; Leising, ME; Schentag, JJ, 1981)

Research

Studies (120)

TimeframeStudies, this research(%)All Research%
pre-199093 (77.50)18.7374
1990's23 (19.17)18.2507
2000's3 (2.50)29.6817
2010's1 (0.83)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Palioura, S1
Nikpoor, N1
Yoo, SH1
Ohtani, T1
Aiba, S1
Mizuashi, M1
Kawamoto, Y1
Tagami, H1
Cotton, RB1
Hazinski, TA1
Morrow, JD1
Roberts, LJ1
Zeldin, DC1
Lindstrom, DP1
Lappalainen, U1
Law, AB1
Steele, S1
Mainra, R1
Gallo, K1
Moist, L1
Lankisch, PG2
Quatrini, M2
Basilisco, G2
Bianchi, PA2
Kaiser, HB1
Weisberg, SC1
Morris, RJ1
Monroe, EW1
Cohen, SH1
Kalbfleisch, J1
Schulz, CI1
Harvey, RP1
Wegs, J1
Schocket, AL1
Piper, DW7
Barr, GD2
Brailski, Kh2
Dimitrov, B2
Mendizova, A2
Kelly, KA1
Malagelada, JR2
Singh, G1
Cook, LJ1
Shuster, S2
Richelson, E1
Kellow, JE1
Cowen, AE2
Ward, M3
Wood, L1
Ananthakrishnan, N1
Van Deventer, GM1
White, A1
Carachi, R1
Young, DG1
Conte, D1
Bardella, MT1
Bozzani, A1
Sherlock, DJ1
Holl-Allen, RT1
Nanivadekar, SA1
Govindani, NF1
Tandon, NH1
Dixit, SD1
Thomas, G1
Szadkowski, M1
Muszyński, J1
Röllinghoff, W1
Paumgartner, G1
Weinstock, JV1
Boros, DL1
Marks, R1
Hetzel, DJ1
Hecker, R1
Shearman, DJ1
Pollard, EJ1
Cowen, A1
Aguilar Angeles, D1
Orea Solano, M1
Chen, PH1
Jenq, YS1
Lin, KY1
Liu, TD1
Wei, CF1
Siauw, CP1
Koo, J1
Lam, SK2
Ong, GB1
Vestal, RE1
Thummel, KE1
Musser, B1
Jue, SG1
Mercer, GD1
Howald, WN1
Nielsen, H1
Madsen, PE1
Christiansen, LA1
Schentag, JJ1
Cerra, FB1
Calleri, GM1
Leising, ME1
French, MA1
Bernhard, H1
Shanahan, F1
Crowe, J1
Jorizzo, JL2
Sams, WM2
Jegasothy, BV1
Olansky, AJ1
Nishi, K1
Amemiya, T1
Mizuguchi, M1
Ooka, T1
Fujimura, M1
Matsuda, T1
Simons, FE1
Sussman, GL1
Simons, KJ1
Russell, PC1
Wright, CE1
Barer, GR1
Howard, P1
Seshadri, P1
Emerson, L1
Morales, A1
Long, DS1
Li, CM1
Yang, QG1
Mine, T2
Kataoka, A1
Fujisaki, J1
Sato, E1
Yasuda, H1
Inaba, Y1
Akimoto, K1
Mashima, H1
Ogata, E1
Kula, Z1
Rudziński, J1
Walasek, L1
Leistra, HP1
Dietrich, WD1
Kondratenko, TY1
Zacharova, IV1
Kuzina, NV1
Severin, ES1
Kornilova, ZCh1
Perelman, MI1
Solomon, SD1
Wolff, S1
Jarboe, LA1
Wolfe, MM1
Lee, RT1
Sekiguchi, H1
Ohsawa, A1
Kobayashi, F1
Ohkubo, H1
Taga, F1
Segami, T1
Suzuki, Y3
Ito, M2
Kirchner, JT1
Kang, JY1
Teng, CH1
Chen, FC1
Onodera, S1
Tanaka, M1
Inaba, N1
Suzuki, T1
Shibata, M1
Yamaura, T1
San Miguel, P1
Sancho, M1
Enriquez, JL1
Fernandez, J1
Gonzalez-Palacios, F1
Kushima, R1
Fujita, T1
Ishihara, M1
Regan, PT1
DiMagno, EP1
Glanzman, SL1
Go, VL1
Phanuphak, P1
Schocket, A1
Kohler, PF1
Bodemar, G1
Walan, A1
Gray, GR1
Smith, IS1
Mackenzie, I1
Gillespie, G1
Misiewicz, JJ1
Commens, CA1
Greaves, MW1
Bardhan, KD1
Saul, DM1
Edwards, JL1
Smith, PM1
Haggie, SJ1
Wyllie, JH1
Duthie, HL1
Fussey, IV1
Maleev, A1
Konstantinova, N1
Vradzhaliev, Zh1
Shipkov, T1
Deredzhan, S1
Cook, J1
Landecker, KD1
Crawford, J1
Hunt, JH1
Gillespie, P1
MacPherson, BR1
Kilam, SK1
Ianev, P1
Karadzhova, R1
Tilkiian, E1
Bonfils, S1
Mignon, M1
Gratton, J1
Okabe, S1
Takeuchi, K1
Murata, T1
Urushidani, T1
Weinstein, GS1
Dupont, PJ1
Hadas, N1
Wapnick, S1
Grosberg, SJ1
Tanner, AR1
Cowlishaw, JL1
Joffe, SN1
Thomson, TJ1
Arakawa, T1
Kobayashi, K1
Dajani, EZ1
Salim, AS1
Szymanski, S1
Lieberman, JA1
Picou, D1
Masiar, S1
Cooper, T1
Wozel, G1
Sahre, EM1
Barth, J1
Pym, B1
Sandstad, J1
Seville, P2
Byth, K2
Middleton, WR1
Talley, NJ1
Salo, OP1
Kauppinen, K1
Männistö, PT1
Kanof, PD1
Coccaro, EF1
Johns, CA1
Davidson, M1
Siever, LJ1
Davis, KL1
Quaranta, JH1
Rohr, AS1
Rachelefsky, GS1
Siegel, SC1
Katz, RM1
Spector, SL1
Mickey, MR1
Novikov, DK1
Dotsenko, EA1
Kolosova, TS1
Antell, LA1
Murabito, AS1
Karlstadt, RG1
Varas, MJ2
Hui, WM1
Ho, J1
Ng, I1
Lau, WY1
Branicki, FJ1
Lai, CL1
Lok, AS1
Ng, MM1
Fok, J1
Chiang, BL1
Chang, MH1
Lin, MI1
Hsu, JY1
Wang, CY1
Wang, TH1
Mulholland, MW1
Reid, BJ1
Levine, DS1
Rubin, CE1
Kobayashi, H1
Adachi, M1
Takahashi, T1
Bianchi Porro, G1
Gordillo, J1
Youngchaiyud, U1
Patty, I1
Tárnok, F1
Deák, G1
Mózsik, G1
Pym, BM1
Toy, S1
Gellatly, R1
Castell, DO1
Lieberman, DA1
Fritsch, WP1
Bolin, TD1
Davis, AE1
Billington, B1
Busman, DC1
Brombacher, PJ1
Munting, JD1
Zhou, ZH1
Singh, DS1
Sunder, S1
Tripathi, KK1
Worning, H1
Olsen, PS1
Poulsen, SS2
Therkelsen, K2
Nexø, E1
Nyrén, O1
Adami, HO1
Bates, S1
Bergström, R1
Gustavsson, S1
Lööf, L1
Nyberg, A1
Lembcke, B1
Göke, B1
Creutzfeldt, W1
Gallagher, CG1
Lennon, JR1
Crowe, JP1
Andrén-Sandberg, A1
Raaberg, L1
Skov Olsen, P1
Kirkegaard, P1
Gillen, P1
Ryan, W1
Peel, AL1
Devlin, HB1
Clarke, B1
Yoong, A1
Marks, IN1
Boyd, E1
Kassir, ZA1
Hentschel, E1
Schütze, K1
Dufek, W1
Weaver, RM1
Temple, JG1
McIntosh, JH1
Hudson, HM1
Ohnishi, K1
Nakayama, T1
Saito, M1
Hatano, H1
Nomura, F1
Iida, S1
Okuda, K1
Murashko, VV1
Zhuravlev, AK1
Shylle, ChI1
Shabashova, NI1
Skliarova, MA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pancreatic Enzyme Replacement Therapy (PERT) for Treatment of Exocrine Pancreatic Insufficiency in Patients With Unresectable Pancreatic Cancer[NCT02985801]Phase 1/Phase 216 participants (Actual)Interventional2016-12-31Terminated (stopped due to Study was terminated due to difficulty in recruiting subjects.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

8 reviews available for cimetidine and Chronic Illness

ArticleYear
Acute and chronic pancreatitis. An update on management.
    Drugs, 1984, Volume: 28, Issue:6

    Topics: Acute Disease; Animals; Aprotinin; Chronic Disease; Cimetidine; Dogs; Enzyme Inhibitors; Enzyme Ther

1984
Medical and surgical treatment of chronic gastric ulcer.
    Clinics in gastroenterology, 1984, Volume: 13, Issue:2

    Topics: Antacids; Chronic Disease; Cimetidine; Gastrectomy; Histamine H2 Antagonists; Humans; Peptic Ulcer;

1984
The use of tricyclic antidepressants in chronic gastrointestinal pain.
    The Journal of clinical psychiatry, 1982, Volume: 43, Issue:8 Pt 2

    Topics: Abdomen; Antidepressive Agents, Tricyclic; Chronic Disease; Cimetidine; Doxepin; Humans; Pain; Pepti

1982
The treatment of chronic peptic ulcer.
    Frontiers of gastrointestinal research, 1980, Volume: 6

    Topics: Antacids; Bismuth; Carbenoxolone; Chronic Disease; Cimetidine; Duodenal Ulcer; Evaluation Studies as

1980
Lobular carcinoma of the male breast associated with the use of cimetidine.
    Virchows Archiv : an international journal of pathology, 1997, Volume: 430, Issue:3

    Topics: Anti-Ulcer Agents; Breast Neoplasms, Male; Carcinoma, Lobular; Chronic Disease; Cimetidine; Humans;

1997
Peptic ulceration and its correlation with symptoms.
    Clinics in gastroenterology, 1978, Volume: 7, Issue:3

    Topics: Carbenoxolone; Chronic Disease; Cimetidine; Clinical Trials as Topic; Duodenal Ulcer; Duodenum; Endo

1978
Refractory peptic ulcers.
    Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians, 1992, Volume: 3, Issue:3

    Topics: Anti-Ulcer Agents; Chronic Disease; Cimetidine; Gastric Mucosa; Humans; Meta-Analysis as Topic; Omep

1992
Highly selective vagotomy and serum gastrin levels.
    Surgery, gynecology & obstetrics, 1987, Volume: 165, Issue:5

    Topics: Adult; Chronic Disease; Cimetidine; Duodenal Ulcer; Evaluation Studies as Topic; Female; Follow-Up S

1987

Trials

41 trials available for cimetidine and Chronic Illness

ArticleYear
Cimetidine does not prevent lung injury in newborn premature infants.
    Pediatric research, 2006, Volume: 59, Issue:6

    Topics: Animals; Chronic Disease; Cimetidine; Humans; Infant, Newborn; Lung Diseases; Placebos; Sheep

2006
Treatment of 'cimetidine-resistant' chronic duodenal ulcers with ranitidine or cimetidine: a randomised multicentre study.
    Gut, 1984, Volume: 25, Issue:10

    Topics: Adolescent; Adult; Aged; Chronic Disease; Cimetidine; Clinical Trials as Topic; Drug Resistance; Duo

1984
Combined H1 and H2 antihistamine therapy in chronic urticaria.
    Archives of dermatology, 1981, Volume: 117, Issue:7

    Topics: Adult; Aged; Chronic Disease; Cimetidine; Double-Blind Method; Drug Therapy, Combination; Evaluation

1981
A controlled trial of therapy in chronic urticaria.
    The Journal of allergy and clinical immunology, 1981, Volume: 68, Issue:4

    Topics: Adult; Chlorpheniramine; Chronic Disease; Cimetidine; Clinical Trials as Topic; Cyproheptadine; Drug

1981
[Treatment of duodenal ulcer with biomet].
    Vutreshni bolesti, 1983, Volume: 22, Issue:5

    Topics: Adult; Anti-Ulcer Agents; Bulgaria; Chronic Disease; Cimetidine; Clinical Trials as Topic; Dose-Resp

1983
Lack of effect of cimetidine in chronic-idiopathic urticaria.
    Acta dermato-venereologica, 1983, Volume: 63, Issue:3

    Topics: Adolescent; Adult; Chlorpheniramine; Chronic Disease; Cimetidine; Double-Blind Method; Drug Therapy,

1983
Comparison of ranitidine and cimetidine in the treatment of chronic gastric ulcer. A double-blind trial.
    Digestion, 1983, Volume: 27, Issue:2

    Topics: Adolescent; Adult; Aged; Alcohol Drinking; Anti-Ulcer Agents; Chronic Disease; Cimetidine; Clinical

1983
Short term therapy with cimetidine of endoscopically proved chronic duodenal ulcer.
    Journal of postgraduate medicine, 1982, Volume: 28, Issue:2

    Topics: Adult; Chronic Disease; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Duodenal Ulcer; E

1982
Treatment of chronic urticaria.
    The British journal of dermatology, 1980, Volume: 102, Issue:2

    Topics: Chlorpheniramine; Chronic Disease; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Drug T

1980
Long-term treatment of duodenal ulcer with cimetidine. Intermittent or continuous therapy?
    The Medical journal of Australia, 1980, Nov-29, Volume: 2, Issue:11

    Topics: Adult; Chronic Disease; Cimetidine; Clinical Trials as Topic; Drug Administration Schedule; Duodenal

1980
Double-blind trial of cimetidine versus tri-potassium di-citrato bismuthate in chronic duodenal ulceration.
    The Medical journal of Australia, 1981, Apr-04, Volume: 1, Issue:7

    Topics: Adult; Aged; Alcohol Drinking; Anti-Ulcer Agents; Bismuth; Chronic Disease; Cimetidine; Clinical Tri

1981
[Cimetidine (clinical trial in 30 patients with chronic urticaria)].
    Alergia, 1981, Volume: 28, Issue:1

    Topics: Adolescent; Adult; Chronic Disease; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Femal

1981
A double blind study on short-term cimetidine in the treatment of duodenal ulcer.
    Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association, 1980, Volume: 79, Issue:12

    Topics: Adult; Aged; Chronic Disease; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Duodenal Ul

1980
Effect of the H2-antagonist cimetidine on the pharmacokinetics and pharmacodynamics of the H1-antagonists hydroxyzine and cetirizine in patients with chronic urticaria.
    The Journal of allergy and clinical immunology, 1995, Volume: 95, Issue:3

    Topics: Adolescent; Adult; Aged; Cetirizine; Chronic Disease; Cimetidine; Double-Blind Method; Drug Combinat

1995
Cimetidine in the treatment of interstitial cystitis.
    Urology, 1994, Volume: 44, Issue:4

    Topics: Administration, Oral; Biopsy; Chronic Disease; Cimetidine; Cystitis; Female; Follow-Up Studies; Huma

1994
[Clinical observation on verrucous gastritis with combined therapy of traditional Chinese and Western medicine].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1994, Volume: 14, Issue:3

    Topics: Adolescent; Adult; Chronic Disease; Cimetidine; Drug Therapy, Combination; Drugs, Chinese Herbal; Fe

1994
Effects of histamine type 2-receptor antagonists cimetidine and famotidine on left ventricular systolic function in chronic congestive heart failure.
    The American journal of cardiology, 1993, Nov-15, Volume: 72, Issue:15

    Topics: Aged; Analysis of Variance; Chronic Disease; Cimetidine; Double-Blind Method; Echocardiography; Famo

1993
Comparative effects of antacids, cimetidine and enteric coating on the therapeutic response to oral enzymes in severe pancreatic insufficiency.
    The New England journal of medicine, 1977, Oct-20, Volume: 297, Issue:16

    Topics: Administration, Oral; Antacids; Celiac Disease; Chronic Disease; Cimetidine; Clinical Trials as Topi

1977
Maintenance treatment of recurrent peptic ulcer by cimetidine.
    Lancet (London, England), 1978, Feb-25, Volume: 1, Issue:8061

    Topics: Adult; Aged; Chronic Disease; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Female; Fol

1978
Long term cimetidine in the management of severe duodenal ulcer dyspepsia.
    Gastroenterology, 1978, Volume: 74, Issue:2 Pt 2

    Topics: Adult; Chronic Disease; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Duodenal Ulcer; D

1978
Peptic ulceration and its correlation with symptoms.
    Clinics in gastroenterology, 1978, Volume: 7, Issue:3

    Topics: Carbenoxolone; Chronic Disease; Cimetidine; Clinical Trials as Topic; Duodenal Ulcer; Duodenum; Endo

1978
Cimetidine in chronic idiopathic urticaria: a randomized double-blind study.
    The British journal of dermatology, 1978, Volume: 99, Issue:6

    Topics: Adolescent; Adult; Aged; Chlorpheniramine; Chronic Disease; Cimetidine; Clinical Trials as Topic; Do

1978
Double-blind comparison of cimetidine and placebo in the maintenance of healing of chronic duodenal ulceration.
    Gut, 1979, Volume: 20, Issue:2

    Topics: Chronic Disease; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Duodenal Ulcer; Female;

1979
[Results of the short-term (28 days) cimetidine treatment of duodenal ulcer].
    Vutreshni bolesti, 1979, Volume: 18, Issue:2

    Topics: Adolescent; Adult; Chronic Disease; Cimetidine; Clinical Trials as Topic; Drug Evaluation; Duodenal

1979
Lack of effect of H2 blockade in chronic urticaria [proceedings].
    The British journal of dermatology, 1979, Volume: 101 Suppl 17

    Topics: Adolescent; Adult; Chlorpheniramine; Chronic Disease; Cimetidine; Clinical Trials as Topic; Double-B

1979
Cimetidine and gastric ulcer healing: a double-blind controlled trial.
    The Medical journal of Australia, 1979, Jul-14, Volume: 2, Issue:1

    Topics: Chronic Disease; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Female; Guanidines; Huma

1979
Efficacy of cimetidine and tri-potassium di-citrato bismuthate (De-Nol) in chronic gastric ulceration: a comparative study.
    The Medical journal of Australia, 1979, Jan-13, Volume: 1, Issue:1

    Topics: Analgesics; Anti-Inflammatory Agents; Bismuth; Chronic Disease; Cimetidine; Citrates; Female; Gastro

1979
[Effectiveness of combination treatment with H1-(Tavegyl) and H2-antagonists (Altramet) in chronic/chronically-recurrent urticaria].
    Dermatologische Monatschrift, 1990, Volume: 176, Issue:11

    Topics: Adult; Chronic Disease; Cimetidine; Clemastine; Double-Blind Method; Female; Humans; Male; Middle Ag

1990
Cost-effectiveness of cimetidine maintenance therapy in chronic gastric and duodenal ulcer.
    Gastroenterology, 1990, Volume: 99, Issue:1

    Topics: Absenteeism; Aged; Chronic Disease; Cimetidine; Cost-Benefit Analysis; Demography; Double-Blind Meth

1990
[Ranitidine and cimetidine in long-term (2 years) maintenance therapy of chronic gastric ulcer].
    Revista espanola de las enfermedades del aparato digestivo, 1989, Volume: 75, Issue:2

    Topics: Adult; Aged; Chronic Disease; Cimetidine; Clinical Trials as Topic; Female; Gastroscopy; Humans; Mal

1989
Effect of sucralfate and cimetidine on duodenal ulcer-associated antral gastritis and Campylobacter pylori.
    The American journal of medicine, 1989, Jun-09, Volume: 86, Issue:6A

    Topics: Adult; Campylobacter; Campylobacter Infections; Chronic Disease; Cimetidine; Clinical Trials as Topi

1989
Famotidine in the treatment of gastric and duodenal ulceration: overview of clinical experience.
    Digestion, 1985, Volume: 32 Suppl 1

    Topics: Acute Disease; Chronic Disease; Cimetidine; Circadian Rhythm; Clinical Trials as Topic; Double-Blind

1985
Comparison of the efficacy of four antihistamines in chronic urticaria.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 1988, Volume: 71, Issue:10

    Topics: Adolescent; Adult; Chlorpheniramine; Chronic Disease; Cimetidine; Clemastine; Double-Blind Method; D

1988
Cimetidine and placebo-cimetidine in the treatment of patients with chronic gastric ulcer (a multiclinical randomized double-blind comparative study).
    Acta medica Hungarica, 1988, Volume: 45, Issue:1

    Topics: Adult; Aged; Chronic Disease; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Female; Hum

1988
The effect of maintenance cimetidine therapy on the medical, social and economic aspects of patients with chronic gastric ulcers. A placebo-controlled prospective study.
    The Medical journal of Australia, 1986, Oct-20, Volume: 145, Issue:8

    Topics: Adult; Aged; Chronic Disease; Cimetidine; Clinical Trials as Topic; Cost-Benefit Analysis; Double-Bl

1986
Medical therapy for chronic reflux esophagitis. Long-term follow-up.
    Archives of internal medicine, 1987, Volume: 147, Issue:10

    Topics: Barrett Esophagus; Chronic Disease; Cimetidine; Clinical Trials as Topic; Drug Therapy, Combination;

1987
Prevention of duodenal ulcer occurrence. Double-blind comparison of ranitidine and cimetidine.
    Journal of clinical gastroenterology, 1987, Volume: 9, Issue:3

    Topics: Adult; Aged; Chronic Disease; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Duodenal Ul

1987
Absence of therapeutic benefit from antacids or cimetidine in non-ulcer dyspepsia.
    The New England journal of medicine, 1986, Feb-06, Volume: 314, Issue:6

    Topics: Adolescent; Adult; Antacids; Chronic Disease; Cimetidine; Clinical Trials as Topic; Double-Blind Met

1986
Therapy of pancreatogenic steatorrhoea: does acid protection of pancreatic enzymes offer any advantage?
    Zeitschrift fur Gastroenterologie, 1986, Volume: 24, Issue:12

    Topics: Celiac Disease; Chronic Disease; Cimetidine; Clinical Trials as Topic; Drug Therapy, Combination; Ex

1986
Endoscopic controlled trial of four drug regimens in the treatment of chronic duodenal ulceration.
    Irish medical journal, 1985, Volume: 78, Issue:6

    Topics: Adolescent; Adult; Aged; Aluminum Hydroxide; Anti-Ulcer Agents; Bismuth; Chronic Disease; Cimetidine

1985
[Recurrence of chronic duodenal ulcer following initial therapy with pirenzepine or cimetidine].
    Zeitschrift fur Gastroenterologie, 1985, Volume: 23, Issue:1

    Topics: Adult; Aged; Benzodiazepinones; Chronic Disease; Cimetidine; Clinical Trials as Topic; Duodenal Ulce

1985

Other Studies

72 other studies available for cimetidine and Chronic Illness

ArticleYear
Chronic Conjunctivitis and "Warts".
    JAMA ophthalmology, 2015, Volume: 133, Issue:9

    Topics: Administration, Oral; Child; Chronic Disease; Cimetidine; Conjunctivitis, Viral; Eye Infections, Vir

2015
Evaluation of the efficacy of antihistamines using human monocyte-derived dendritic cells stimulated with histamine.
    Journal of the American Academy of Dermatology, 2003, Volume: 49, Issue:2

    Topics: Adolescent; Adult; Antigens, CD; B7-2 Antigen; Cetirizine; Chronic Disease; Cimetidine; Dendritic Ce

2003
Effect of N-acetylcysteine on renal function in patients with chronic kidney disease.
    Nephrology (Carlton, Vic.), 2007, Volume: 12, Issue:5

    Topics: Acetylcysteine; Aged; Chronic Disease; Cimetidine; Creatinine; Cystatin C; Cystatins; Drug Synergism

2007
Cimetidine in chronic urticaria.
    Lancet (London, England), 1980, Jul-26, Volume: 2, Issue:8187

    Topics: Chronic Disease; Cimetidine; Guanidines; Humans; Receptors, Histamine H1; Receptors, Histamine H2; U

1980
Another look at peptic ulcer.
    Australian family physician, 1981, Volume: 10, Issue:8

    Topics: Antacids; Bismuth; Chronic Disease; Cimetidine; Colloids; Duodenal Ulcer; Female; Furans; Histamine

1981
H2 blockers in chronic urticaria.
    International journal of dermatology, 1984, Volume: 23, Issue:9

    Topics: Adolescent; Adult; Carbolines; Chronic Disease; Cimetidine; Histamine H1 Antagonists; Histamine H2 A

1984
Cimetidine in gastric ulcer: a note of caution.
    Journal of the Indian Medical Association, 1984, Volume: 82, Issue:6

    Topics: Chronic Disease; Cimetidine; Humans; Recurrence; Stomach Ulcer

1984
Approaches to the long-term treatment of duodenal ulcer disease.
    The American journal of medicine, 1984, Nov-19, Volume: 77, Issue:5B

    Topics: Age Factors; Chronic Disease; Cimetidine; Duodenal Ulcer; Female; Gastric Mucosa; Humans; Male; Recu

1984
Duodenal ulceration presenting in childhood longterm follow-up.
    Journal of pediatric surgery, 1984, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Antacids; Child; Child, Preschool; Chronic Disease; Cimetidine; Duodenal Ulcer; F

1984
Secretin-induced gastrin response in the Zollinger-Ellison syndrome and chronic duodenal ulcer patients before and after cimetidine treatment.
    The American journal of gastroenterology, 1984, Volume: 79, Issue:5

    Topics: Adolescent; Adult; Chronic Disease; Cimetidine; Duodenal Ulcer; Female; Gastrins; Humans; Male; Midd

1984
Duodenal ulcer perforation whilst on cimetidine therapy.
    The British journal of surgery, 1984, Volume: 71, Issue:8

    Topics: Adult; Aged; Chronic Disease; Cimetidine; Drainage; Duodenal Ulcer; Female; Humans; Male; Middle Age

1984
[Effect of cimetidine on the exocrine and endocrine functions of the pancreas in healthy persons and in patients with chronic pancreatitis].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1982, Aug-23, Volume: 37, Issue:29-30

    Topics: Adult; Chronic Disease; Cimetidine; Female; Guanidines; Humans; Islets of Langerhans; Male; Middle A

1982
Inhibition of drug metabolism by cimetidine in man: dependence on pretreatment microsomal liver function.
    European journal of clinical investigation, 1982, Volume: 12, Issue:5

    Topics: Aged; Aminopyrine; Breath Tests; Chronic Disease; Cimetidine; Depression, Chemical; Female; Guanidin

1982
Heterogeneity of the granulomatous response in the liver, colon, ileum, and ileal Peyer's patches to schistosome eggs in murine schistosomiasis mansoni.
    Journal of immunology (Baltimore, Md. : 1950), 1981, Volume: 127, Issue:5

    Topics: Animals; Antilymphocyte Serum; Chronic Disease; Cimetidine; Colon; Complement System Proteins; Cyclo

1981
Cimetidine versus surgery for recurrent ulcer after gastric surgery.
    Annals of surgery, 1982, Volume: 195, Issue:4

    Topics: Adult; Aged; Chronic Disease; Cimetidine; Drug Evaluation; Duodenal Ulcer; Female; Follow-Up Studies

1982
Stable isotope methodology in a pharmacokinetic study of the interaction of theophylline and cimetidine.
    Biomedical mass spectrometry, 1982, Volume: 9, Issue:8

    Topics: Carbon Isotopes; Chromatography, High Pressure Liquid; Chronic Disease; Cimetidine; Drug Interaction

1982
The parietal cells in duodenal ulcer patients. A quantitative ultrastructural study before and during treatment with cimetidine.
    Scandinavian journal of gastroenterology, 1980, Volume: 15, Issue:7

    Topics: Adult; Chronic Disease; Cimetidine; Duodenal Ulcer; Duodenum; Guanidines; Humans; Middle Aged

1980
Age, disease, and cimetidine disposition in healthy subjects and chronically ill patients.
    Clinical pharmacology and therapeutics, 1981, Volume: 29, Issue:6

    Topics: Adolescent; Adult; Age Factors; Aged; Blood-Brain Barrier; Chronic Disease; Cimetidine; Guanidines;

1981
Cimetidine and the control of pain in chronic relapsing pancreatitis.
    The New England journal of medicine, 1981, Sep-10, Volume: 305, Issue:11

    Topics: Chronic Disease; Cimetidine; Guanidines; Humans; Pain; Pancreatitis; Recurrence

1981
Cimetidine as an immunomodulator: chronic mucocutaneous candidiasis as a model.
    Annals of internal medicine, 1980, Volume: 92, Issue:2 Pt 1

    Topics: Adult; Candidiasis, Cutaneous; Chronic Disease; Cimetidine; Guanidines; Humans; Immunity, Cellular;

1980
[A case of chronic persistent cough caused by gastro-esophageal reflux].
    Nihon Kyobu Shikkan Gakkai zasshi, 1995, Volume: 33, Issue:6

    Topics: Aged; Chronic Disease; Cimetidine; Cough; Female; Gastroesophageal Reflux; Histamine H2 Antagonists;

1995
Histamine induced pulmonary vasodilatation in the rat: site of action and changes in chronic hypoxia.
    The European respiratory journal, 1994, Volume: 7, Issue:6

    Topics: Animals; Chronic Disease; Cimetidine; Histamine; Hypoxia; In Vitro Techniques; Lung; Male; p-Methoxy

1994
Healing of chronic gastric ulcer depends on gastric mucosal prostaglandin synthesis.
    Hepato-gastroenterology, 1994, Volume: 41, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Autoradiography; Chronic Disease; Cimetidine; Dinoproston

1994
[Comparative evaluation of sucralfate (Venter) and cimetidine (Altramet) efficiency in treatment of chronic erosive gastritis].
    Przeglad lekarski, 1994, Volume: 51, Issue:2

    Topics: Adult; Aged; Chronic Disease; Cimetidine; Female; Gastritis; Gastroscopy; Humans; Male; Middle Aged;

1994
Effect of the histamine antagonist cimetidine on infarct size in the rat.
    Journal of neurotrauma, 1993,Spring, Volume: 10, Issue:1

    Topics: Animals; Blood Pressure; Carbon Dioxide; Cerebral Infarction; Chronic Disease; Cimetidine; Histamine

1993
The study of histamine H1- and H2-receptors in human lung cancer.
    Biochemistry and molecular biology international, 1993, Volume: 31, Issue:3

    Topics: Adenocarcinoma; Adult; Airway Obstruction; Chronic Disease; Cimetidine; Humans; Lung Neoplasms; Midd

1993
[Influence of KU-1257 on the recurrence and relapse of acetic acid-induced chronic gastric ulcers in rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1996, Volume: 107, Issue:2

    Topics: Acetates; Acetic Acid; Animals; Chronic Disease; Cimetidine; Histamine H2 Antagonists; Male; Phenylu

1996
Simultaneous evaluation of gastric and duodenal ulcers-healing activities of anti-ulcer agents in rats.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:1

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Atropine; Chronic Disease; Cimetidine; Duodenal Ulcer; Hist

1996
Drug therapy for chronic urticaria.
    Postgraduate medicine, 1996, Volume: 100, Issue:4

    Topics: Chronic Disease; Cimetidine; Histamine H2 Antagonists; Humans; Prednisone; Urticaria

1996
Effect of capsaicin and cimetidine on the healing of acetic acid induced gastric ulceration in the rat.
    Gut, 1996, Volume: 38, Issue:6

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Capsaicin; Chronic Disease; Cimetidine; Drug Therapy, Combi

1996
[Effect of a novel antiulcer drug, lafutidine, on experimental chronic gastritis in rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1997, Volume: 109, Issue:1

    Topics: Acetamides; Ammonia; Animals; Anti-Ulcer Agents; Cell Count; Chronic Disease; Cimetidine; Famotidine

1997
Relationship between healing of acetic acid-induced chronic gastric ulcer and connexin.
    Journal of clinical gastroenterology, 1997, Volume: 25 Suppl 1

    Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Chronic Disease; Cimetidine; Connexins; Epidermal Growth Fa

1997
Anti-ulcer effects of antioxidants: effect of probucol.
    European journal of pharmacology, 1998, Aug-07, Volume: 354, Issue:2-3

    Topics: Acetic Acid; Acute Disease; Animals; Anti-Ulcer Agents; Antioxidants; Chronic Disease; Cimetidine; D

1998
Treatment of chronic idiopathic urticaria with combined H1 and H2 blockers.
    Clinical allergy, 1978, Volume: 8, Issue:5

    Topics: Adult; Chronic Disease; Cimetidine; Cyproheptadine; Drug Therapy, Combination; Female; Histamine H1

1978
Effect of cimetidine on chronic gastric ulcers produced experimentally in rats.
    Canadian journal of surgery. Journal canadien de chirurgie, 1979, Volume: 22, Issue:4

    Topics: Acetates; Administration, Oral; Animals; Chronic Disease; Cimetidine; Epithelium; Guanidines; Male;

1979
Cimetidine in chronic mucocutaneous candidiasis.
    Archives of dermatology, 1979, Volume: 115, Issue:10

    Topics: Adult; Candidiasis, Cutaneous; Chronic Disease; Cimetidine; Guanidines; Humans

1979
[Our experience in the treatment of duodenal ulcer with cimetidine].
    Vutreshni bolesti, 1979, Volume: 18, Issue:5

    Topics: Adolescent; Adult; Child; Chronic Disease; Cimetidine; Drug Evaluation; Duodenal Ulcer; Female; Guan

1979
Cimetidine treatment of acute and chronic Zollinger-Ellison syndrome.
    World journal of surgery, 1979, Sep-20, Volume: 3, Issue:5

    Topics: Acute Disease; Benzodiazepines; Chronic Disease; Cimetidine; Duodenal Neoplasms; Gastrectomy; Gastri

1979
Effects of cimetidine on healing of chronic gastric and duodenal ulcers in dogs.
    The American journal of digestive diseases, 1978, Volume: 23, Issue:2

    Topics: Animals; Chronic Disease; Cimetidine; Dogs; Duodenal Ulcer; Guanidines; Male; Stomach Ulcer; Wound H

1978
Cimetidine for ever (and ever and ever...)?
    British medical journal, 1978, Jun-03, Volume: 1, Issue:6125

    Topics: Chronic Disease; Cimetidine; Duodenal Ulcer; Guanidines; Humans; Time Factors

1978
Cimetidine plus propantheline for chronic pancreatitis.
    The New England journal of medicine, 1978, May-25, Volume: 298, Issue:21

    Topics: Chronic Disease; Cimetidine; Drug Therapy, Combination; Guanidines; Humans; Pancreatitis; Propanthel

1978
Cimetidine in pancreatitis.
    The New England journal of medicine, 1978, Aug-31, Volume: 299, Issue:9

    Topics: Animals; Chronic Disease; Cimetidine; Guanidines; Humans; Pancreatitis; Rats

1978
Cimetidine--is it the final common pathway for duodenal ulcers.
    Scottish medical journal, 1977, Volume: 22, Issue:4

    Topics: Chronic Disease; Cimetidine; Costs and Cost Analysis; Duodenal Ulcer; Guanidines; Humans; Vagotomy

1977
Therapeutic uses of cimetidine.
    Scottish medical journal, 1977, Volume: 22, Issue:4

    Topics: Acute Disease; Chronic Disease; Cimetidine; Drug Evaluation; Gastritis; Guanidines; Humans; Peptic U

1977
A possible new approach to the problem of refractory peptic ulceration. A role for free radical scavengers?
    Scottish medical journal, 1991, Volume: 36, Issue:1

    Topics: Adult; Allopurinol; Chronic Disease; Cimetidine; Dimethyl Sulfoxide; Duodenal Ulcer; Female; Free Ra

1991
A case report of cimetidine-induced clozapine toxicity.
    The Journal of clinical psychiatry, 1991, Volume: 52, Issue:1

    Topics: Adult; Chronic Disease; Cimetidine; Clozapine; Drug Interactions; Drug Therapy, Combination; Humans;

1991
Cimetidine increases the plasma concentration of hydroxyzine.
    Acta dermato-venereologica, 1986, Volume: 66, Issue:4

    Topics: Chronic Disease; Cimetidine; Drug Interactions; Drug Therapy, Combination; Humans; Hydroxyzine; Urti

1986
Cyclic-AMP production by polymorphonuclear leukocytes in psychiatric disorders.
    Biological psychiatry, 1989, Feb-15, Volume: 25, Issue:4

    Topics: Adult; Alprostadil; Chronic Disease; Cimetidine; Cyclic AMP; Depressive Disorder; Female; Humans; Is

1989
The natural history and response to therapy of chronic urticaria and angioedema.
    Annals of allergy, 1989, Volume: 62, Issue:5

    Topics: Adrenal Cortex Hormones; Adult; Angioedema; Chronic Disease; Cimetidine; Female; Histamine H1 Antago

1989
[Treatment of chronic urticaria of unknown origin with a combination of H1 and H2 antihistaminics].
    Klinicheskaia meditsina, 1989, Volume: 67, Issue:4

    Topics: Adult; Chronic Disease; Cimetidine; Drug Therapy, Combination; Female; Histamine H1 Antagonists; Hum

1989
Depression not associated with cimetidine.
    Pennsylvania medicine, 1989, Volume: 92, Issue:11

    Topics: Aged; Aged, 80 and over; Chronic Disease; Cimetidine; Depression; Humans; Product Surveillance, Post

1989
Chronic duodenal ulcer in children: clinical observation and response to treatment.
    Journal of pediatric gastroenterology and nutrition, 1989, Volume: 8, Issue:2

    Topics: Adolescent; Antacids; Child; Chronic Disease; Cimetidine; Duodenal Ulcer; Female; Humans; Male; Recu

1989
Elevated gastric acid secretion in patients with Barrett's metaplastic epithelium.
    Digestive diseases and sciences, 1989, Volume: 34, Issue:9

    Topics: Barrett Esophagus; Chronic Disease; Cimetidine; Female; Gastric Acid; Gastric Acidity Determination;

1989
[Biotidin treatment of duodenal ulcer].
    Vutreshni bolesti, 1989, Volume: 28, Issue:3

    Topics: Adult; Chronic Disease; Cimetidine; Drug Evaluation; Duodenal Ulcer; Duodenoscopy; Female; Gastric M

1989
[The effects of an H2 receptor antagonist (cimetidine) in asthmatic patients].
    Arerugi = [Allergy], 1985, Volume: 34, Issue:1

    Topics: Adolescent; Adult; Aged; Asthma; Chronic Disease; Cimetidine; Female; Gastritis; Histamine H1 Antago

1985
[Cimetidine, ranitidine and somatostatin in the medical treatment of acute and chronic Zollinger-Ellison syndrome].
    Revista espanola de las enfermedades del aparato digestivo, 1987, Volume: 72, Issue:6

    Topics: Acute Disease; Adult; Chronic Disease; Cimetidine; Humans; Male; Ranitidine; Somatostatin; Zollinger

1987
Long-term therapy for chronic gastroesophageal reflux.
    Archives of internal medicine, 1987, Volume: 147, Issue:10

    Topics: Chronic Disease; Cimetidine; Drug Therapy, Combination; Esophagogastric Junction; Gastroesophageal R

1987
[Causal therapy of chronic gastritis?].
    Zeitschrift fur Gastroenterologie, 1988, Volume: 26, Issue:8

    Topics: Amoxicillin; Bismuth; Campylobacter Infections; Chronic Disease; Cimetidine; Drug Therapy, Combinati

1988
[Therapeutic effect of weiyankang and cimetidine in the treatment of chronic superficial gastritis].
    Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, 1987, Volume: 7, Issue:11

    Topics: Adult; Chronic Disease; Cimetidine; Double-Blind Method; Drugs, Chinese Herbal; Female; Gastritis; H

1987
Tricyclic antidepressant therapy in duodenal ulcer.
    Journal of the Indian Medical Association, 1987, Volume: 85, Issue:9

    Topics: Adult; Chronic Disease; Cimetidine; Dibenzazepines; Duodenal Ulcer; Female; Humans; Male; Middle Age

1987
Exocrine pancreatic substitution: facts and controversies.
    Scandinavian journal of gastroenterology. Supplement, 1986, Volume: 126

    Topics: Adult; Chronic Disease; Cimetidine; Drug Therapy, Combination; Exocrine Pancreatic Insufficiency; Hu

1986
Effect of sialoadenectomy and synthetic human urogastrone on healing of chronic gastric ulcers in rats.
    Gut, 1986, Volume: 27, Issue:12

    Topics: Animals; Chronic Disease; Cimetidine; Combined Modality Therapy; Epidermal Growth Factor; Female; Ga

1986
Chronic erosive gastritis: a clinical study.
    The American journal of gastroenterology, 1987, Volume: 82, Issue:4

    Topics: Adolescent; Adult; Aged; Barium Sulfate; Chronic Disease; Cimetidine; Female; Follow-Up Studies; Gas

1987
Enzyme substitution in pancreatic disease.
    Digestion, 1987, Volume: 37 Suppl 1

    Topics: Chronic Disease; Cimetidine; Exocrine Pancreatic Insufficiency; Humans; Malabsorption Syndromes; Pan

1987
Effect of antisecretory agents and vagotomy on healing of "chronic" cysteamine-induced duodenal ulcers in rats.
    Digestive diseases and sciences, 1986, Volume: 31, Issue:7

    Topics: Animals; Anti-Ulcer Agents; Benzimidazoles; Brunner Glands; Chronic Disease; Cimetidine; Cysteamine;

1986
Duodenal ulcer perforation: the effect of H2 antagonists?
    Annals of the Royal College of Surgeons of England, 1986, Volume: 68, Issue:5

    Topics: Acute Disease; Aged; Chronic Disease; Cimetidine; Duodenal Ulcer; Female; Humans; Male; Middle Aged;

1986
Prolonged cholestasis and cimetidine.
    Digestive diseases and sciences, 1987, Volume: 32, Issue:3

    Topics: Cholestasis; Chronic Disease; Cimetidine; Humans; Male; Middle Aged

1987
Mucosal protective agents in the long-term management of gastric ulcer.
    The Medical journal of Australia, 1985, Feb-04, Volume: 142 Spec No

    Topics: Aluminum; Aluminum Hydroxide; Anti-Ulcer Agents; Bismuth; Carbenoxolone; Chronic Disease; Cimetidine

1985
Proximal gastric vagotomy in patients resistant to cimetidine.
    The British journal of surgery, 1985, Volume: 72, Issue:3

    Topics: Adolescent; Adult; Aged; Chronic Disease; Cimetidine; Duodenal Ulcer; Female; Humans; Male; Middle A

1985
Factors relevant to the prognosis of chronic duodenal ulcer.
    Digestion, 1985, Volume: 31, Issue:1

    Topics: Age Factors; Alcohol Drinking; Analgesics; Bismuth; Carbenoxolone; Chronic Disease; Cimetidine; Drug

1985
Effects of cimetidine and ranitidine on splanchnic hemodynamics in patients with chronic liver disease.
    The American journal of gastroenterology, 1985, Volume: 80, Issue:4

    Topics: Chronic Disease; Cimetidine; Female; Hemodynamics; Humans; Liver Circulation; Liver Diseases; Male;

1985
[Blood viscosity indicators in patients with gastric and duodenal diseases].
    Terapevticheskii arkhiv, 1985, Volume: 57, Issue:2

    Topics: Adolescent; Adult; Blood Viscosity; Chronic Disease; Cimetidine; Cyproheptadine; Duodenal Ulcer; Fem

1985