cimetidine has been researched along with Choriocarcinoma in 1 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Choriocarcinoma: A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cimetidine was 18 times more potent than clonidine in inhibiting the JAR cell Na(+)-H+ exchanger." | 1.28 | Relative sensitivity to inhibition by cimetidine and clonidine differentiates between the two types of Na(+)-H+ exchangers in cultured cells. ( Ganapathy, V; Leibach, FH; Mahesh, VB; Nair, CN; Ramamoorthy, S; Tiruppathi, C, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ramamoorthy, S | 1 |
| Tiruppathi, C | 1 |
| Nair, CN | 1 |
| Mahesh, VB | 1 |
| Leibach, FH | 1 |
| Ganapathy, V | 1 |
1 other study available for cimetidine and Choriocarcinoma
| Article | Year |
|---|---|
Relative sensitivity to inhibition by cimetidine and clonidine differentiates between the two types of Na(+)-H+ exchangers in cultured cells.
Topics: Animals; Carrier Proteins; Cell Line; Choriocarcinoma; Cimetidine; Clonidine; HeLa Cells; Humans; Op | 1991 |