cimetidine has been researched along with Cell Transformation, Neoplastic in 4 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cimetidine is known to have an anti-tumor effect on certain types of malignancies, though on hepatocellular carcinomas (HCCs), its effect remains unclear." | 7.74 | Anti-tumor effects of cimetidine on hepatocellular carcinomas in diethylnitrosamine-treated rats. ( Adachi, K; Amano, Y; Furuta, K; Ishihara, S; Ishine, J; Kinoshita, Y; Miyake, T; Okamoto, E; Sato, S, 2008) |
| "Cimetidine is known to have an anti-tumor effect on certain types of malignancies, though on hepatocellular carcinomas (HCCs), its effect remains unclear." | 3.74 | Anti-tumor effects of cimetidine on hepatocellular carcinomas in diethylnitrosamine-treated rats. ( Adachi, K; Amano, Y; Furuta, K; Ishihara, S; Ishine, J; Kinoshita, Y; Miyake, T; Okamoto, E; Sato, S, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Furuta, K | 1 |
| Sato, S | 1 |
| Miyake, T | 1 |
| Okamoto, E | 1 |
| Ishine, J | 1 |
| Ishihara, S | 1 |
| Amano, Y | 1 |
| Adachi, K | 1 |
| Kinoshita, Y | 1 |
| Barrows, LR | 1 |
| Gombar, CT | 1 |
| Magee, PN | 2 |
| Taylor, RH | 1 |
| Menzies-Gow, N | 1 |
| Lovell, D | 1 |
| La Brooy, SJ | 1 |
| Misiewicz, JJ | 1 |
1 review available for cimetidine and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Role of pharmacokinetics and DNA dosimetry in relating in vitro to in vivo actions of N-nitroso compounds.
Topics: Animals; Biotransformation; Cell Transformation, Neoplastic; Cimetidine; DNA, Neoplasm; Dose-Respons | 1985 |
3 other studies available for cimetidine and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Anti-tumor effects of cimetidine on hepatocellular carcinomas in diethylnitrosamine-treated rats.
Topics: Animals; Anticarcinogenic Agents; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Cimeti | 2008 |
Mutation, DNA labeling, and transformation of BHK-21/CL 13 cells by MNNG, and nitrosocimetidine.
Topics: Animals; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cimetidine; Cricetinae; DNA; Gua | 1982 |
Misleading response of malignant gastric ulcers to cimetidine.
Topics: Adult; Cell Transformation, Neoplastic; Cimetidine; Diagnosis, Differential; Diagnostic Errors; Fema | 1978 |