cimetidine has been researched along with Carcinoma in 13 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Carcinoma: A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Previous studies have suggested that cimetidine, a histamine-2 receptor antagonist with immunostimulatory effects, may improve survival in patients with colorectal carcinoma." | 9.09 | Randomized trial of preoperative cimetidine in patients with colorectal carcinoma with quantitative assessment of tumor-associated lymphocytes. ( Adams, WJ; Cherian, M; Dwerryhouse, SJ; Finlay, IG; Kelly, MD; King, DW; King, J; Lubowski, DZ; Morris, DL, 1999) |
| "The present study was designed to elucidate the effect of cimetidine and PSK on T-cell subsets, interleukin-2 (IL-2) production and its receptor in peripheral blood lymphocytes (PBL) from patients with advanced ovarian carcinoma during the course of chemotherapy." | 7.67 | [Effects of cimetidine and PSK on interleukin-2 production by PBL in patients with advanced ovarian carcinoma during the course of chemotherapy]. ( Iwano, I; Kato, K; Kikuchi, Y; Kita, T; Kizawa, I; Miyauchi, M; Oomori, K, 1987) |
| "The effect of cimetidine on basal and pentagastrin-stimulated serum immunoreactive calcitonin (S-iCT) concentrations was studied in six patients with medullary carcinoma of the thyroid (MCT)." | 7.66 | No effect of cimetidine on calcitonin secretion from medullary thyroid carcinoma. ( Emmertsen, K; Hansen, HH; Mosekilde, L; Nielsen, HE, 1980) |
| "Previous studies have suggested that cimetidine, a histamine-2 receptor antagonist with immunostimulatory effects, may improve survival in patients with colorectal carcinoma." | 5.09 | Randomized trial of preoperative cimetidine in patients with colorectal carcinoma with quantitative assessment of tumor-associated lymphocytes. ( Adams, WJ; Cherian, M; Dwerryhouse, SJ; Finlay, IG; Kelly, MD; King, DW; King, J; Lubowski, DZ; Morris, DL, 1999) |
| "The present study was designed to elucidate the effect of cimetidine and PSK on T-cell subsets, interleukin-2 (IL-2) production and its receptor in peripheral blood lymphocytes (PBL) from patients with advanced ovarian carcinoma during the course of chemotherapy." | 3.67 | [Effects of cimetidine and PSK on interleukin-2 production by PBL in patients with advanced ovarian carcinoma during the course of chemotherapy]. ( Iwano, I; Kato, K; Kikuchi, Y; Kita, T; Kizawa, I; Miyauchi, M; Oomori, K, 1987) |
| "The histamine-2 receptor antagonist cimetidine (10(-5)M) and the prostaglandin synthesis inhibitor indomethacin (10(-8)M) augmented natural killer cell activity in the majority of healthy controls and patients with advanced melanoma and in a lower frequency of patients with colorectal carcinoma." | 3.67 | Influence in vitro on NK and K cell activities by cimetidine and indomethacin with and without simultaneous exposure to interferon. ( Flodgren, P; Sjögren, HO, 1985) |
| "The effect of cimetidine on basal and pentagastrin-stimulated serum immunoreactive calcitonin (S-iCT) concentrations was studied in six patients with medullary carcinoma of the thyroid (MCT)." | 3.66 | No effect of cimetidine on calcitonin secretion from medullary thyroid carcinoma. ( Emmertsen, K; Hansen, HH; Mosekilde, L; Nielsen, HE, 1980) |
| " Weekly paclitaxel at a dose of 67 mg/m2/week was found to have a better safety profile and seemed to be as effective as the equivalently dosed schedule every 3 weeks." | 2.70 | Randomized trial of single agent paclitaxel given weekly versus every three weeks and with peroral versus intravenous steroid premedication to patients with ovarian cancer previously treated with platinum. ( Andersson, H; Boman, K; Parö, G; Puistola, U; Ridderheim, M; Rosenberg, P; Sorbe, B, 2002) |
| "Gastro-oesophageal reflux disease (GERD) is common in obese patients." | 2.41 | Gastro-oesophageal reflux disease in obesity: pathophysiological and therapeutic considerations. ( Barak, N; Ehrenpreis, ED; Harrison, JR; Sitrin, MD, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (46.15) | 18.7374 |
| 1990's | 4 (30.77) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barak, N | 1 |
| Ehrenpreis, ED | 1 |
| Harrison, JR | 1 |
| Sitrin, MD | 1 |
| Rosenberg, P | 1 |
| Andersson, H | 1 |
| Boman, K | 1 |
| Ridderheim, M | 1 |
| Sorbe, B | 1 |
| Puistola, U | 1 |
| Parö, G | 1 |
| Sulochana, G | 1 |
| Kalavathy, R | 1 |
| Padmanabhan, L | 1 |
| Emmertsen, K | 1 |
| Nielsen, HE | 1 |
| Mosekilde, L | 1 |
| Hansen, HH | 1 |
| Wagner, S | 1 |
| Beil, W | 1 |
| Mai, UE | 1 |
| Bokemeyer, C | 1 |
| Meyer, HJ | 1 |
| Manns, MP | 1 |
| Teicher, BA | 1 |
| Holden, SA | 1 |
| Goff, DA | 1 |
| Wright, JE | 1 |
| Tretyakov, O | 1 |
| Ayash, LJ | 1 |
| Anesini, C | 1 |
| Genaro, A | 1 |
| Cremaschi, G | 1 |
| Zubillaga, M | 1 |
| Boccio, J | 1 |
| Sterin-Borda, L | 1 |
| Borda, E | 1 |
| Kelly, MD | 1 |
| King, J | 1 |
| Cherian, M | 1 |
| Dwerryhouse, SJ | 1 |
| Finlay, IG | 1 |
| Adams, WJ | 1 |
| King, DW | 1 |
| Lubowski, DZ | 1 |
| Morris, DL | 1 |
| Moon, C | 1 |
| Verschraegen, CF | 1 |
| Bevers, M | 1 |
| Freedman, R | 1 |
| Kudelka, AP | 1 |
| Kavanagh, JJ | 1 |
| Armitage, JO | 1 |
| Sidner, RD | 1 |
| Klimczak, J | 1 |
| Kikuchi, Y | 1 |
| Kizawa, I | 1 |
| Oomori, K | 1 |
| Iwano, I | 1 |
| Kita, T | 1 |
| Miyauchi, M | 1 |
| Kato, K | 1 |
| Flodgren, P | 1 |
| Sjögren, HO | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Long Term Effects of Laparoscopic Roux-en-Y Gastric Bypass on Gastro-esophageal Reflux: Clinical Impact of Weakly Acidic Reflux[NCT02618044] | 86 participants (Actual) | Observational | 2006-05-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for cimetidine and Carcinoma
| Article | Year |
|---|---|
Gastro-oesophageal reflux disease in obesity: pathophysiological and therapeutic considerations.
Topics: Body Composition; Carcinoma; Cimetidine; Esophageal Neoplasms; Gastroesophageal Reflux; Hernia, Hiat | 2002 |
2 trials available for cimetidine and Carcinoma
| Article | Year |
|---|---|
Randomized trial of single agent paclitaxel given weekly versus every three weeks and with peroral versus intravenous steroid premedication to patients with ovarian cancer previously treated with platinum.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemot | 2002 |
Randomized trial of preoperative cimetidine in patients with colorectal carcinoma with quantitative assessment of tumor-associated lymphocytes.
Topics: Adjuvants, Immunologic; Antineoplastic Agents; Carcinoma; Cimetidine; Colorectal Neoplasms; Dose-Res | 1999 |
10 other studies available for cimetidine and Carcinoma
| Article | Year |
|---|---|
Protein & aminoacid concentrations in the gastric aspirate in the diagnosis of gastric carcinoma.
Topics: Amino Acids; Carcinoma; Cimetidine; Gastric Juice; Humans; Proteins; Stomach Neoplasms | 1983 |
No effect of cimetidine on calcitonin secretion from medullary thyroid carcinoma.
Topics: Adult; Aged; Calcitonin; Carcinoma; Cimetidine; Female; Guanidines; Humans; Male; Middle Aged; Penta | 1980 |
Interaction between Helicobacter pylori and human gastric epithelial cells in culture: effect of antiulcer drugs.
Topics: Anti-Ulcer Agents; Bacterial Adhesion; Carcinoma; Cells, Cultured; Cimetidine; Duodenal Ulcer; Epith | 1994 |
Antitumor efficacy and pharmacokinetic analysis of 4-hydroperoxycyclophosphamide in comparison with cyclophosphamide +/- hepatic enzyme effectors.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Pro | 1996 |
"In vivo" and "in vitro" antitumoral action of Larrea divaricata Cav.
Topics: Analysis of Variance; Animals; Antineoplastic Agents, Phytogenic; Carcinoma; Cell Division; Cimetidi | 1996 |
Use of docetaxel (Taxotere) in patients with paclitaxel (Taxol) hypersensitivity.
Topics: Adult; Antineoplastic Agents, Phytogenic; Carcinoma; Cimetidine; Cystadenocarcinoma; Dexamethasone; | 2000 |
Antitumour effect of cimetidine.
Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Carcinoma; Carcinoma, Bronchogenic; Cimetidine; Female | 1979 |
[Use of cimetidine with histamine in 4 patients with inoperable neoplasms of the upper part of the digestive tract].
Topics: Adenocarcinoma; Aged; Carcinoma; Cimetidine; Drug Therapy, Combination; Esophageal Neoplasms; Histam | 1985 |
[Effects of cimetidine and PSK on interleukin-2 production by PBL in patients with advanced ovarian carcinoma during the course of chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cimetidine; Cisplatin; Cyclophosphamide; | 1987 |
Influence in vitro on NK and K cell activities by cimetidine and indomethacin with and without simultaneous exposure to interferon.
Topics: Antibody-Dependent Cell Cytotoxicity; Carcinoma; Cimetidine; Colonic Neoplasms; Cytotoxicity, Immuno | 1985 |