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cimetidine and Carcinoid Tumor

cimetidine has been researched along with Carcinoid Tumor in 5 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Carcinoid Tumor: A usually small, slow-growing neoplasm composed of islands of rounded, oxyphilic, or spindle-shaped cells of medium size, with moderately small vesicular nuclei, and covered by intact mucosa with a yellow cut surface. The tumor can occur anywhere in the gastrointestinal tract (and in the lungs and other sites); approximately 90% arise in the appendix. It is now established that these tumors are of neuroendocrine origin and derive from a primitive stem cell. (From Stedman, 25th ed & Holland et al., Cancer Medicine, 3d ed, p1182)

Research Excerpts

ExcerptRelevanceReference
" The lack of significant adverse effects has revealed a degree of tolerability that, to write a review of the adverse effects, poses a difficult task."2.39A comparative overview of the adverse effects of antiulcer drugs. ( Piper, DW, 1995)
"Pulmonary carcinoids are rarely associated with carcinoid syndromes and even less commonly with carcinoid crisis."1.29Carcinoid crisis after biopsy of a bronchial carcinoid. ( Karmy-Jones, R; Vallières, E, 1993)
"Fundic argyrophil carcinoid tumors developed in the course of a 5-year continuous treatment with high dosages of H2-antagonists in a well-documented case of Zollinger-Ellison syndrome with primary hyperparathyroidism, high basal acid output, and serum gastrin."1.27Development of gastric argyrophil carcinoid tumors in a case of Zollinger-Ellison syndrome with primary hyperparathyroidism during long-term antisecretory treatment. ( Bonfils, S; Bonnefond, A; Labeille, D; Lehy, T; Mignon, M; Ruszniewski, P, 1987)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's2 (40.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wingert, TD1
Morley, JE1
Hershman, JM1
Pyles, JD1
Silberman, HR1
Feldman, JM1
Piper, DW1
Karmy-Jones, R1
Vallières, E1
Mignon, M1
Lehy, T1
Bonnefond, A1
Ruszniewski, P1
Labeille, D1
Bonfils, S1

Reviews

1 review available for cimetidine and Carcinoid Tumor

ArticleYear
A comparative overview of the adverse effects of antiulcer drugs.
    Drug safety, 1995, Volume: 12, Issue:2

    Topics: Antacids; Anti-Ulcer Agents; Carcinoid Tumor; Cimetidine; Humans; Misoprostol; Omeprazole; Ranitidin

1995

Other Studies

4 other studies available for cimetidine and Carcinoid Tumor

ArticleYear
Histamine antagonists and carcinoid flush.
    The New England journal of medicine, 1980, Jan-24, Volume: 302, Issue:4

    Topics: Carcinoid Tumor; Cimetidine; Diphenhydramine; Drug Therapy, Combination; Female; Guanidines; Humans;

1980
Histamine antagonists and carcinoid flush.
    The New England journal of medicine, 1980, Jan-24, Volume: 302, Issue:4

    Topics: Adult; Carcinoid Tumor; Cimetidine; Diphenhydramine; Drug Therapy, Combination; Guanidines; Humans;

1980
Carcinoid crisis after biopsy of a bronchial carcinoid.
    The Annals of thoracic surgery, 1993, Volume: 56, Issue:6

    Topics: Biopsy; Bronchial Neoplasms; Carcinoid Tumor; Cimetidine; Female; Humans; Malignant Carcinoid Syndro

1993
Development of gastric argyrophil carcinoid tumors in a case of Zollinger-Ellison syndrome with primary hyperparathyroidism during long-term antisecretory treatment.
    Cancer, 1987, Jun-01, Volume: 59, Issue:11

    Topics: Carcinoid Tumor; Cell Division; Cimetidine; Female; Gastrectomy; Humans; Hyperparathyroidism; Middle

1987