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cimetidine and Canine Diseases

cimetidine has been researched along with Canine Diseases in 16 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Research Excerpts

ExcerptRelevanceReference
"A double-blind study was conducted to compare gastric ulcer healing time in nontreated dogs with that in dogs treated with either cimetidine or omeprazole."7.68Comparison of effects of cimetidine and omeprazole on mechanically created gastric ulceration and on aspirin-induced gastritis in dogs. ( Bright, RM; DeNovo, RC; Jenkins, CC; Patton, CS; Rohrbach, BW, 1991)
"A 20-month-old German shepherd with primary pancreatic acinar atrophy and exocrine pancreatic insufficiency that was treated with pancreatic enzyme supplementation, vitamin B12, and cimetidine developed oral bleeding."3.73Oral ulceration and bleeding associated with pancreatic enzyme supplementation in a German shepherd with pancreatic acinar atrophy. ( Snead, E, 2006)
"A double-blind study was conducted to compare gastric ulcer healing time in nontreated dogs with that in dogs treated with either cimetidine or omeprazole."3.68Comparison of effects of cimetidine and omeprazole on mechanically created gastric ulceration and on aspirin-induced gastritis in dogs. ( Bright, RM; DeNovo, RC; Jenkins, CC; Patton, CS; Rohrbach, BW, 1991)
" During pentobarbital anesthesia, 2 pulmonary hemodynamic studies were conducted on each dog with a sequence of baseline, hypoxia with FlO2 = 10%, hyperoxia with FlO2 = 100%, a second baseline, treatment with either diphenhydramine (D) or cimetidine (C), and another hypoxia."3.68Postadulticide pulmonary hypertension of canine heartworm disease: successful treatment with oxygen and failure of antihistamines. ( Rawlings, CA; Tackett, RL, 1990)
" Methylprednisolone sodium succinate was given at a dosage of 30 mg/kg of body weight prior to myelography, followed by a second full or half dose 2 to 4 hours later at clinician discretion."2.68Clinical evaluation of cimetidine, sucralfate, and misoprostol for prevention of gastrointestinal tract bleeding in dogs undergoing spinal surgery. ( Bostwick, DR; Hanson, SM; Smith, MO; Twedt, DC, 1997)
" Dose-response relationships to histamine were done in rings of canine pulmonary artery from heartworm and control dogs, in the presence and absence of endothelial cells, the H1 receptor blocker tripelennamine, or the H2 receptor blocker cimetidine."1.30Dirofilaria immitis: heartworm infection converts histamine-induced constriction to endothelium-dependent relaxation in canine pulmonary artery. ( Kaiser, L; Williams, JF, 1998)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19908 (50.00)18.7374
1990's5 (31.25)18.2507
2000's3 (18.75)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
De Zan, G1
Zappulli, V1
Cavicchioli, L1
Di Martino, L1
Ros, E1
Conforto, G1
Castagnaro, M1
Trumel, C1
Bourgès-Abella, N1
Touron, C1
Lanore, D1
Geffré, A1
Diquelou, A1
Guelfi, JF1
Braun, JP1
Snead, E1
Van Stee, EW1
Papich, MG1
Tams, TR1
Pidgeon, G2
Strombeck, DR1
Whitley, NT1
Hanson, SM1
Bostwick, DR1
Twedt, DC1
Smith, MO1
Kaiser, L1
Williams, JF1
Cooper, JR1
Mattsson, JL1
Jenkins, CC1
DeNovo, RC1
Patton, CS1
Bright, RM1
Rohrbach, BW1
Rawlings, CA1
Tackett, RL1
Woolliscroft, G1
McArthur, S1
Pilsworth, RC1
Lehner, RP1

Trials

1 trial available for cimetidine and Canine Diseases

ArticleYear
Clinical evaluation of cimetidine, sucralfate, and misoprostol for prevention of gastrointestinal tract bleeding in dogs undergoing spinal surgery.
    American journal of veterinary research, 1997, Volume: 58, Issue:11

    Topics: Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Blood Loss, Surgical;

1997

Other Studies

15 other studies available for cimetidine and Canine Diseases

ArticleYear
Gastric B-cell lymphoma with Mott cell differentiation in a dog.
    Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc, 2009, Volume: 21, Issue:5

    Topics: Animals; Anti-Ulcer Agents; Cell Differentiation; Cimetidine; Dog Diseases; Dogs; Euthanasia; Gastro

2009
Adverse haematological effects of vinblastine, prednisolone and cimetidine treatment: a retrospective study in fourteen dogs with mast cell tumours.
    Journal of veterinary medicine. A, Physiology, pathology, clinical medicine, 2005, Volume: 52, Issue:6

    Topics: Adjuvants, Immunologic; Animals; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic;

2005
Oral ulceration and bleeding associated with pancreatic enzyme supplementation in a German shepherd with pancreatic acinar atrophy.
    The Canadian veterinary journal = La revue veterinaire canadienne, 2006, Volume: 47, Issue:6

    Topics: Animals; Atrophy; Cimetidine; Dog Diseases; Dogs; Enzyme Inhibitors; Exocrine Pancreatic Insufficien

2006
Alternative to corticosteroids in the management of pruritus in dogs.
    Veterinary medicine, small animal clinician : VM, SAC, 1981, Volume: 76, Issue:3

    Topics: Animals; Chlorpheniramine; Cimetidine; Dog Diseases; Dogs; Glucocorticoids; Guanidines; Histamine H1

1981
Cimetidine for treatment of colonic perforation?
    Journal of the American Veterinary Medical Association, 1984, Apr-15, Volume: 184, Issue:8

    Topics: Adrenal Cortex Hormones; Animals; Cimetidine; Colonic Diseases; Dog Diseases; Dogs; Intestinal Perfo

1984
Management of liver disease in dogs and cats.
    Modern veterinary practice, 1984, Volume: 65, Issue:2

    Topics: Acetylcysteine; Adrenal Cortex Hormones; Animals; Anti-Bacterial Agents; Bacterial Infections; Cat D

1984
Evaluation of treatment for pancreatic exocrine insufficiency in dogs with ligated pancreatic ducts.
    American journal of veterinary research, 1982, Volume: 43, Issue:3

    Topics: Animals; Bicarbonates; Bile Acids and Salts; Cimetidine; Dog Diseases; Dogs; Exocrine Pancreatic Ins

1982
Effect of diet on exocrine pancreatic insufficiency in dogs.
    Journal of the American Veterinary Medical Association, 1982, Aug-01, Volume: 181, Issue:3

    Topics: Animal Feed; Animals; Antacids; Cimetidine; Dog Diseases; Dogs; Exocrine Pancreatic Insufficiency; F

1982
Megaoesophagus and glucocorticoid-deficient hypoadrenocorticism in a dog.
    The Journal of small animal practice, 1995, Volume: 36, Issue:3

    Topics: Adrenal Insufficiency; Adrenocorticotropic Hormone; Animals; Cimetidine; Dexamethasone; Dog Diseases

1995
Dirofilaria immitis: heartworm infection converts histamine-induced constriction to endothelium-dependent relaxation in canine pulmonary artery.
    Experimental parasitology, 1998, Volume: 88, Issue:2

    Topics: Animals; Cimetidine; Dirofilariasis; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Endotheli

1998
Control of radiation-induced emesis with promethazine, cimetidine, thiethylperazine, or naloxone.
    American journal of veterinary research, 1979, Volume: 40, Issue:8

    Topics: Animals; Chemoreceptor Cells; Cimetidine; Dog Diseases; Dogs; Guanidines; Male; Naloxone; Promethazi

1979
Comparison of effects of cimetidine and omeprazole on mechanically created gastric ulceration and on aspirin-induced gastritis in dogs.
    American journal of veterinary research, 1991, Volume: 52, Issue:5

    Topics: Administration, Oral; Animals; Aspirin; Cimetidine; Dog Diseases; Dogs; Double-Blind Method; Gastrit

1991
Postadulticide pulmonary hypertension of canine heartworm disease: successful treatment with oxygen and failure of antihistamines.
    American journal of veterinary research, 1990, Volume: 51, Issue:10

    Topics: Animals; Arsenamide; Blood Pressure; Cimetidine; Diphenhydramine; Dirofilariasis; Dog Diseases; Dogs

1990
Flurbiprofen toxicity in a dog.
    The Veterinary record, 1987, Aug-01, Volume: 121, Issue:5

    Topics: Animals; Cimetidine; Dog Diseases; Dogs; Flurbiprofen; Propionates

1987
Use of cimetidine as an aid to the control of pancreatic insufficiency in a German shepherd bitch.
    The Veterinary record, 1986, Sep-06, Volume: 119, Issue:10

    Topics: Animals; Cimetidine; Dog Diseases; Dogs; Exocrine Pancreatic Insufficiency; Female; Pancreatic Juice

1986