Page last updated: 2024-10-25

cimetidine and Bronchial Spasm

cimetidine has been researched along with Bronchial Spasm in 8 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Bronchial Spasm: Spasmodic contraction of the smooth muscle of the bronchi.

Research Excerpts

ExcerptRelevanceReference
"The effect of an H1 antihistamine, an H2 antihistamine, and the combination of the two drugs on both histamine-induced bronchoconstriction and dermal whealing was examined in five patients with mild asthma."9.05A comparison of the actions of H1 and H2 antihistamines on histamine-induced bronchoconstriction and cutaneous wheal response in asthmatic patients. ( Nathan, RA; Schocket, AL; Segall, N, 1981)
"We compared the effects of two histamine receptor blocking agents, chlorpheniramine (H1) and cimetidine (H2) on the airways of healthy and asthmatic subjects."9.05Histamine blocking agents in healthy and asthmatic subjects. ( Brown, S; Gerstenhaber, B; Lach, E; Schachter, EN, 1982)
" During the first 60 min of bypass, hypotension (40-45 mm Hg) was observed in spite of phenylephrine 14 mg."7.67Bronchospasm and hypotension during cardiopulmonary bypass after preoperative cimetidine and labetalol therapy. ( Durant, PA; Joucken, K, 1984)
"The effect of an H1 antihistamine, an H2 antihistamine, and the combination of the two drugs on both histamine-induced bronchoconstriction and dermal whealing was examined in five patients with mild asthma."5.05A comparison of the actions of H1 and H2 antihistamines on histamine-induced bronchoconstriction and cutaneous wheal response in asthmatic patients. ( Nathan, RA; Schocket, AL; Segall, N, 1981)
"We compared the effects of two histamine receptor blocking agents, chlorpheniramine (H1) and cimetidine (H2) on the airways of healthy and asthmatic subjects."5.05Histamine blocking agents in healthy and asthmatic subjects. ( Brown, S; Gerstenhaber, B; Lach, E; Schachter, EN, 1982)
" During the first 60 min of bypass, hypotension (40-45 mm Hg) was observed in spite of phenylephrine 14 mg."3.67Bronchospasm and hypotension during cardiopulmonary bypass after preoperative cimetidine and labetalol therapy. ( Durant, PA; Joucken, K, 1984)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19908 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nathan, RA1
Segall, N1
Schocket, AL1
Schachter, EN2
Brown, S2
Zuskin, E1
Beck, GJ1
Buck, M1
Kolack, B1
Bouhuys, A1
Rassmann, E1
ten Hoff, H1
Priester, G1
Sill, V1
Qvist, N1
Storm, K1
Williams, JC1
Conaty, JM1
Townshend-Piala, P1
Durant, PA1
Joucken, K1
Lach, E1
Gerstenhaber, B1
Kambam, JR1
Dymond, R1
Krestow, M1
Handte, RE1

Trials

3 trials available for cimetidine and Bronchial Spasm

ArticleYear
A comparison of the actions of H1 and H2 antihistamines on histamine-induced bronchoconstriction and cutaneous wheal response in asthmatic patients.
    The Journal of allergy and clinical immunology, 1981, Volume: 67, Issue:3

    Topics: Asthma; Bronchial Provocation Tests; Bronchial Spasm; Chlorpheniramine; Cimetidine; Clinical Trials

1981
Cimethidine pre-anesthetic. A prophylactic method against Mendelson's syndrome in cesarean section.
    Acta obstetricia et gynecologica Scandinavica, 1983, Volume: 62, Issue:2

    Topics: Anesthesia, Obstetrical; Bronchial Spasm; Cesarean Section; Cimetidine; Clinical Trials as Topic; Do

1983
Histamine blocking agents in healthy and asthmatic subjects.
    Chest, 1982, Volume: 82, Issue:2

    Topics: Asthma; Bronchi; Bronchial Spasm; Chlorpheniramine; Cimetidine; Forced Expiratory Flow Rates; Guanid

1982

Other Studies

5 other studies available for cimetidine and Bronchial Spasm

ArticleYear
The effect of mediator modifying drugs in cotton bract-induced bronchospasm.
    Chest, 1981, Volume: 79, Issue:4 Suppl

    Topics: Adult; Bronchial Spasm; Cimetidine; Cromolyn Sodium; Gossypium; Histamine H1 Antagonists; Humans; Ma

1981
[The effect of an H2-receptor blocking agent on the acetylcholine and histamine provocation test in the normal and hyperactive bronchial system (author's transl)].
    Praxis und Klinik der Pneumologie, 1982, Volume: 36, Issue:4

    Topics: Acetylcholine; Adult; Aged; Airway Resistance; Bronchial Provocation Tests; Bronchial Spasm; Cimetid

1982
On the mechanism of histamine-induced bronchodilation in conscious guinea-pigs.
    Agents and actions, 1984, Volume: 15, Issue:3-4

    Topics: Aerosols; Animals; Bronchial Spasm; Bronchodilator Agents; Chlorpheniramine; Cimetidine; Guinea Pigs

1984
Bronchospasm and hypotension during cardiopulmonary bypass after preoperative cimetidine and labetalol therapy.
    British journal of anaesthesia, 1984, Volume: 56, Issue:8

    Topics: Bronchial Spasm; Cardiopulmonary Bypass; Cimetidine; Drug Interactions; Humans; Hypotension; Intraop

1984
Efficacy of histamine H1 and H2 receptor blockers in the anesthetic management during operation for hydatid cysts of liver and lungs.
    Southern medical journal, 1988, Volume: 81, Issue:8

    Topics: Adult; Anaphylaxis; Anesthesia; Blood Pressure; Bronchial Spasm; Central Venous Pressure; Cimetidine

1988