cimetidine has been researched along with Brain Swelling in 5 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The possibility that histamine plays a role in the formation of traumatic brain edema was investigated in the rat." | 7.67 | Role of histamine in traumatic brain edema. An experimental study in the rat. ( Chansouria, JP; Dey, PK; Mohanty, S; Olsson, Y; Sharma, HS; Singh, S, 1989) |
| "The possibility that histamine plays a role in the formation of traumatic brain edema was investigated in the rat." | 3.67 | Role of histamine in traumatic brain edema. An experimental study in the rat. ( Chansouria, JP; Dey, PK; Mohanty, S; Olsson, Y; Sharma, HS; Singh, S, 1989) |
| "In cimetidine-pretreated animals, the cerebral blood flow was significantly elevated and the plasma and brain 5-hydroxytryptamine (serotonin) levels were slightly but significantly reduced as compared with the untreated stressed group." | 1.28 | Histamine modulates heat stress-induced changes in blood-brain barrier permeability, cerebral blood flow, brain oedema and serotonin levels: an experimental study in conscious young rats. ( Cervos-Navarro, J; Dey, PK; Nyberg, F; Sharma, HS, 1992) |
| "Pretreatment with histamine H2 receptor antagonist cimetidine significantly reduced the extravasation of both the tracers and thwarted the increase of brain water content as compared to the untreated group." | 1.28 | Role of histamine in pathophysiology of heat stress in rats. ( Cervós-Navarro, J; Sharma, HS, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Csanda, E | 1 |
| Patnaik, R | 1 |
| Mohanty, S | 2 |
| Sharma, HS | 4 |
| Nyberg, F | 1 |
| Cervos-Navarro, J | 2 |
| Dey, PK | 2 |
| Singh, S | 1 |
| Chansouria, JP | 1 |
| Olsson, Y | 1 |
5 other studies available for cimetidine and Brain Swelling
| Article | Year |
|---|---|
Radiation brain edema.
Topics: Animals; Brain; Brain Edema; Cats; Cimetidine; Dogs; Electrons; Evans Blue; Metiamide; Rabbits; Rats | 1980 |
Blockade of histamine H2 receptors attenuate blood-brain barrier permeability, cerebral blood flow disturbances, edema formation and cell reactions following hyperthermic brain injury in the rat.
Topics: Animals; Blood-Brain Barrier; Brain; Brain Edema; Brain Injuries; Capillary Permeability; Cimetidine | 2000 |
Histamine modulates heat stress-induced changes in blood-brain barrier permeability, cerebral blood flow, brain oedema and serotonin levels: an experimental study in conscious young rats.
Topics: Animals; Blood-Brain Barrier; Brain; Brain Edema; Cimetidine; Histamine; Hot Temperature; Male; Orga | 1992 |
Role of histamine in pathophysiology of heat stress in rats.
Topics: Animals; Blood-Brain Barrier; Body Water; Brain; Brain Edema; Cimetidine; Histamine; Hot Temperature | 1991 |
Role of histamine in traumatic brain edema. An experimental study in the rat.
Topics: Animals; Brain Edema; Brain Injuries; Cimetidine; Histamine; Male; Pyrilamine; Rats; Rats, Inbred St | 1989 |