cimetidine has been researched along with Brain Ischemia in 2 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We demonstrated that famotidine or cimetidine as compared with saline did not affect the pattern or extent of hyperemia after ischemia." | 3.68 | Histamine-2-receptor blockade does not affect hyperemia after cerebral ischemia in young swine. ( Helfaer, MA; Kirsch, JR; Traystman, RJ; Tung, WS, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shibata, S | 1 |
| Watanabe, S | 1 |
| Tung, WS | 1 |
| Helfaer, MA | 1 |
| Kirsch, JR | 1 |
| Traystman, RJ | 1 |
2 other studies available for cimetidine and Brain Ischemia
| Article | Year |
|---|---|
A neuroprotective effect of histamine H1 receptor antagonist on ischemia-induced decrease in 2-deoxyglucose uptake in rat hippocampal slices.
Topics: Animals; Brain Ischemia; Cimetidine; Deoxyglucose; Hippocampus; Histamine H1 Antagonists; Histamine | 1993 |
Histamine-2-receptor blockade does not affect hyperemia after cerebral ischemia in young swine.
Topics: Animals; Brain Ischemia; Cerebrovascular Circulation; Cimetidine; Famotidine; Hyperemia; Intracrania | 1993 |