cimetidine has been researched along with Brain Diseases in 11 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Brain Diseases: Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Albendazole is considered the drug of choice for neurocysticercosis." | 9.08 | Therapy for neurocysticercosis: pharmacokinetic interaction of albendazole sulfoxide with dexamethasone. ( Bonato, PS; Lanchote, VL; Marques, MP; Takayanagui, OM, 1997) |
| "A patient had neurocysticercosis complicated by a seizure disorder requiring anticonvulsants; previous praziquantel therapy (50 mg/kg/day) had failed to eradicate the disease." | 7.69 | Cimetidine-induced rise in praziquantel levels in a patient with neurocysticercosis being treated with anticonvulsants. ( Adubofour, KO; Bikin, DS; Dachman, WD; Johnson, CH; Mullin, PD; Winograd, M, 1994) |
| "Albendazole is considered the drug of choice for neurocysticercosis." | 5.08 | Therapy for neurocysticercosis: pharmacokinetic interaction of albendazole sulfoxide with dexamethasone. ( Bonato, PS; Lanchote, VL; Marques, MP; Takayanagui, OM, 1997) |
| "A patient had neurocysticercosis complicated by a seizure disorder requiring anticonvulsants; previous praziquantel therapy (50 mg/kg/day) had failed to eradicate the disease." | 3.69 | Cimetidine-induced rise in praziquantel levels in a patient with neurocysticercosis being treated with anticonvulsants. ( Adubofour, KO; Bikin, DS; Dachman, WD; Johnson, CH; Mullin, PD; Winograd, M, 1994) |
| "Cimetidine-related neurotoxicity may be characterized by signs of affective dysfunction, toxic delusional state and/or delirium, confusion and/or amnestic signs, coma, epileptic phenomena and focal neurological signs." | 1.27 | Cimetidine neurotoxicity. EEG and behaviour aspects. ( Kamphuisen, HA; Van Sweden, B, 1984) |
| "Pretreatment with cimetidine resulted in a significant, dose-dependent decrease in the CD50 of lidocaine, whereas ranitidine pretreatment did not significantly alter the lidocaine CD50." | 1.27 | Effects of cimetidine and ranitidine on local anesthetic central nervous system toxicity in mice. ( Kim, KC; Tasch, MD, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (72.73) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Merillon, MC | 1 |
| Coupier, L | 1 |
| Lauru, Y | 1 |
| Garbay, M | 1 |
| Van Sweden, B | 1 |
| Kamphuisen, HA | 1 |
| Rushton, AR | 1 |
| Smith, S | 1 |
| Legros, JJ | 1 |
| Le Mairo, M | 1 |
| Rousseau, JJ | 1 |
| Waucquez, JL | 1 |
| Sonnenblick, M | 1 |
| Rosin, AJ | 1 |
| Weissberg, N | 1 |
| Lareng, L | 1 |
| Jeannot, MJ | 1 |
| Clergue, ML | 1 |
| Scavazza, R | 1 |
| Fouet, P | 1 |
| Elefterion, A | 1 |
| Dachman, WD | 1 |
| Adubofour, KO | 1 |
| Bikin, DS | 1 |
| Johnson, CH | 1 |
| Mullin, PD | 1 |
| Winograd, M | 1 |
| Takayanagui, OM | 1 |
| Lanchote, VL | 1 |
| Marques, MP | 1 |
| Bonato, PS | 1 |
| Duval, L | 1 |
| Hautecoeur, P | 1 |
| Mahieu, M | 1 |
| Chan, KH | 1 |
| Mann, KS | 1 |
| Kim, KC | 1 |
| Tasch, MD | 1 |
1 trial available for cimetidine and Brain Diseases
| Article | Year |
|---|---|
Therapy for neurocysticercosis: pharmacokinetic interaction of albendazole sulfoxide with dexamethasone.
Topics: Adolescent; Adult; Albendazole; Anthelmintics; Anti-Inflammatory Agents; Brain Diseases; Cimetidine; | 1997 |
10 other studies available for cimetidine and Brain Diseases
| Article | Year |
|---|---|
[Neuropsychic complications of cimetidine. Precautions in its use].
Topics: Aged; Brain Diseases; Cimetidine; Guanidines; Humans; Male; Mental Disorders; Middle Aged | 1983 |
Cimetidine neurotoxicity. EEG and behaviour aspects.
Topics: Brain; Brain Diseases; Cimetidine; Confusion; Delusions; Electroencephalography; Epilepsy; Female; H | 1984 |
Pseudohypoparathyroidism, cimetidine, and neurologic toxicity.
Topics: Adolescent; Brain Diseases; Cimetidine; Female; Guanidines; Humans; Pseudohypoparathyroidism | 1983 |
Cimetidine neurotoxicity and anticholinergic activity.
Topics: Brain Diseases; Cimetidine; Guanidines; Humans; Receptors, Cholinergic; Receptors, Histamine H2 | 1982 |
Neurological and psychiatric side effects of cimetidine--report of 3 cases with review of the literature.
Topics: Aged; Brain Diseases; Cimetidine; Coma; Female; Guanidines; Humans; Male; Mental Disorders | 1982 |
[Cimetidine and gastric secretion in acutely ill neurosurgical patients].
Topics: Adolescent; Adult; Aged; Brain Diseases; Brain Injuries; Cimetidine; Gastric Juice; Guanidines; Huma | 1982 |
Cimetidine-induced rise in praziquantel levels in a patient with neurocysticercosis being treated with anticonvulsants.
Topics: Adult; Anticonvulsants; Brain Diseases; Cimetidine; Cysticercosis; Drug Therapy, Combination; Humans | 1994 |
[Cimetidine-induced hyperammonemic encephalopathy].
Topics: Adult; Ammonia; Analgesics, Non-Narcotic; Brain Diseases; Cimetidine; Humans; Male; Time Factors | 1999 |
Failure of cimetidine prophylaxis in neurosurgery.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Brain Diseases; Cimetidine; Drug Evaluati | 1989 |
Effects of cimetidine and ranitidine on local anesthetic central nervous system toxicity in mice.
Topics: Anesthetics, Local; Animals; Brain Diseases; Cimetidine; Dose-Response Relationship, Drug; Drug Inte | 1986 |