cimetidine has been researched along with Bradycardia in 19 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Bradycardia: Cardiac arrhythmias that are characterized by excessively slow HEART RATE, usually below 50 beats per minute in human adults. They can be classified broadly into SINOATRIAL NODE dysfunction and ATRIOVENTRICULAR BLOCK.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cimetidine and ranitidine are specific and potent H2-receptor antagonists widely used in the effective therapy of peptic ulcer disease." | 8.77 | Actions of cimetidine and ranitidine at some cholinergic sites: implications in toxicology and anesthesia. ( Cheah, LS; Gwee, MC, 1986) |
| "Cimetidine and ranitidine are specific and potent H2-receptor antagonists widely used in the effective therapy of peptic ulcer disease." | 4.77 | Actions of cimetidine and ranitidine at some cholinergic sites: implications in toxicology and anesthesia. ( Cheah, LS; Gwee, MC, 1986) |
| "A 70-year-old woman free of renal or hepatic dysfunction developed reversible mental confusion, sinus bradycardia, and extreme QT interval prolongation following initiation of intravenous cimetidine 1200 mg daily." | 3.67 | Cimetidine-related cardiac conduction disturbances and confusion. ( Cohen, N; Eshkoly, M; Golik, A; Modai, D; Scapa, E; Theitler, J, 1989) |
| " The warfarin enantiomers were given separately as single doses (15 mg) alone and during chronic administration of cimetidine (1 g day-1)." | 2.66 | Stereoselective interaction between the R enantiomer of warfarin and cimetidine. ( Breckenridge, AM; Cholerton, S; Choonara, IA; Haynes, BP; Park, BK, 1986) |
| " He developed symptoms of atropine poisoning in the form of hallucinations, confusion and dilated pupils when the total dosage of atropine was 2." | 1.27 | Atropine toxicity in acute cervical spinal injury. ( Baker, JH; Silver, JR, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (78.95) | 18.7374 |
| 1990's | 4 (21.05) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hiss, J | 1 |
| Hepler, BR | 1 |
| Falkowski, AJ | 1 |
| Sunshine, I | 1 |
| Jawad, F | 1 |
| Baker, JH | 1 |
| Silver, JR | 1 |
| Levi, R | 1 |
| Trzeciakowski, JP | 1 |
| Karch, FE | 1 |
| Becker, LA | 1 |
| Nikolic, G | 1 |
| Singh, JB | 1 |
| Hinrichsen, H | 1 |
| Halabi, A | 1 |
| Kirch, W | 1 |
| Reding, P | 1 |
| Devroede, C | 1 |
| Barbier, P | 1 |
| Bournerias, F | 1 |
| Ganeval, D | 1 |
| Danan, G | 1 |
| Jefferys, DB | 1 |
| Vale, JA | 1 |
| Stimmesse, B | 1 |
| Daoudal, P | 1 |
| Neidhardt, A | 1 |
| Ory, JP | 1 |
| al-Waili, NS | 1 |
| Hasan, NU | 1 |
| Iberti, TJ | 1 |
| Zeisler, J | 1 |
| Wiggins, RC | 1 |
| Glatfelter, A | 1 |
| Campbell, AM | 1 |
| Kunkel, RG | 1 |
| Ulevitch, RJ | 1 |
| Cohen, N | 1 |
| Modai, D | 1 |
| Golik, A | 1 |
| Eshkoly, M | 1 |
| Theitler, J | 1 |
| Scapa, E | 1 |
| Gwee, MC | 1 |
| Cheah, LS | 1 |
| Choonara, IA | 1 |
| Cholerton, S | 1 |
| Haynes, BP | 1 |
| Breckenridge, AM | 1 |
| Park, BK | 1 |
| Tanner, LA | 1 |
| Arrowsmith, JB | 1 |
2 reviews available for cimetidine and Bradycardia
| Article | Year |
|---|---|
Clinical aspects of cardiovascular effects of H2-receptor antagonists.
Topics: Animals; Atrioventricular Node; Blood Pressure; Bradycardia; Cardiovascular System; Cimetidine; Elec | 1995 |
Actions of cimetidine and ranitidine at some cholinergic sites: implications in toxicology and anesthesia.
Topics: Anesthesia; Animals; Antihypertensive Agents; Bradycardia; Cholinesterase Inhibitors; Cimetidine; Co | 1986 |
1 trial available for cimetidine and Bradycardia
| Article | Year |
|---|---|
Stereoselective interaction between the R enantiomer of warfarin and cimetidine.
Topics: Administration, Oral; Bradycardia; Cimetidine; Drug Eruptions; Drug Interactions; Half-Life; Humans; | 1986 |
16 other studies available for cimetidine and Bradycardia
| Article | Year |
|---|---|
Fatal bradycardia after intentional overdose of cimetidine and diazepam.
Topics: Adult; Bradycardia; Cimetidine; Diazepam; Drug Synergism; Female; Guanidines; Humans; Suicide | 1982 |
Ranitidine and side effects.
Topics: Bradycardia; Cimetidine; Furans; Humans; Prolactin; Ranitidine | 1983 |
Atropine toxicity in acute cervical spinal injury.
Topics: Adult; Atropine; Bradycardia; Cimetidine; Hallucinations; Humans; Male; Spinal Injuries | 1984 |
Cimetidine and sinus-node function.
Topics: Animals; Bradycardia; Cimetidine; Dogs; Guanidines; Haplorhini; Heart Rate; Humans; Receptors, Hista | 1980 |
Bradycardia associated with cimetidine.
Topics: Aged; Bradycardia; Cimetidine; Gastrointestinal Hemorrhage; Guanidines; Humans; Male | 1980 |
Cimetidine, vasopressin and chronotropic incompetence.
Topics: Arrhythmias, Cardiac; Bradycardia; Cimetidine; Coronary Disease; Drug Therapy, Combination; Electroc | 1982 |
Bradycardia after cimetidine.
Topics: Bradycardia; Cimetidine; Gastrointestinal Hemorrhage; Guanidines; Humans; Male; Middle Aged | 1977 |
[Fatal cardiac arrhythmia during treatment with cimetidine].
Topics: Adult; Arrhythmias, Cardiac; Bradycardia; Cardiac Complexes, Premature; Cimetidine; Female; Guanidin | 1978 |
Cimetidine and bradycardia.
Topics: Adult; Bradycardia; Cimetidine; Guanidines; Humans; Male; Middle Aged | 1978 |
[Bradycardia during treatment with cimetidine].
Topics: Aged; Bradycardia; Cimetidine; Guanidines; Humans; Male | 1978 |
Cimetidine and bradycardia.
Topics: Adult; Bradycardia; Cimetidine; Female; Humans; Male; Middle Aged | 1992 |
Hemodynamic effects of H2-receptor antagonists.
Topics: Bradycardia; Cimetidine; Critical Care; Gastric Acid; Histamine H2 Antagonists; Humans; Hypotension; | 1990 |
Correction: Cimetidine-induced bradycardia.
Topics: Bradycardia; Cimetidine; Humans; Nitroglycerin | 1990 |
Acute hypotension due to platelet serotonin-induced chemoreflexes after intravenous injection of dextran sulfate in the rabbit.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Autonomic Nervous System; Blood Platelets; Bradyc | 1985 |
Cimetidine-related cardiac conduction disturbances and confusion.
Topics: Aged; Bradycardia; Cimetidine; Cognition Disorders; Confusion; Female; Humans; Pre-Excitation Syndro | 1989 |
Bradycardia and H2 antagonists.
Topics: Bradycardia; Cimetidine; Humans; Product Surveillance, Postmarketing; Ranitidine | 1988 |