cimetidine has been researched along with Bradyarrhythmia in 19 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cimetidine and ranitidine are specific and potent H2-receptor antagonists widely used in the effective therapy of peptic ulcer disease." | 8.77 | Actions of cimetidine and ranitidine at some cholinergic sites: implications in toxicology and anesthesia. ( Cheah, LS; Gwee, MC, 1986) |
| "Cimetidine and ranitidine are specific and potent H2-receptor antagonists widely used in the effective therapy of peptic ulcer disease." | 4.77 | Actions of cimetidine and ranitidine at some cholinergic sites: implications in toxicology and anesthesia. ( Cheah, LS; Gwee, MC, 1986) |
| "A 70-year-old woman free of renal or hepatic dysfunction developed reversible mental confusion, sinus bradycardia, and extreme QT interval prolongation following initiation of intravenous cimetidine 1200 mg daily." | 3.67 | Cimetidine-related cardiac conduction disturbances and confusion. ( Cohen, N; Eshkoly, M; Golik, A; Modai, D; Scapa, E; Theitler, J, 1989) |
| " The warfarin enantiomers were given separately as single doses (15 mg) alone and during chronic administration of cimetidine (1 g day-1)." | 2.66 | Stereoselective interaction between the R enantiomer of warfarin and cimetidine. ( Breckenridge, AM; Cholerton, S; Choonara, IA; Haynes, BP; Park, BK, 1986) |
| " He developed symptoms of atropine poisoning in the form of hallucinations, confusion and dilated pupils when the total dosage of atropine was 2." | 1.27 | Atropine toxicity in acute cervical spinal injury. ( Baker, JH; Silver, JR, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (78.95) | 18.7374 |
| 1990's | 4 (21.05) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hiss, J | 1 |
| Hepler, BR | 1 |
| Falkowski, AJ | 1 |
| Sunshine, I | 1 |
| Jawad, F | 1 |
| Baker, JH | 1 |
| Silver, JR | 1 |
| Levi, R | 1 |
| Trzeciakowski, JP | 1 |
| Karch, FE | 1 |
| Becker, LA | 1 |
| Nikolic, G | 1 |
| Singh, JB | 1 |
| Hinrichsen, H | 1 |
| Halabi, A | 1 |
| Kirch, W | 1 |
| Reding, P | 1 |
| Devroede, C | 1 |
| Barbier, P | 1 |
| Bournerias, F | 1 |
| Ganeval, D | 1 |
| Danan, G | 1 |
| Jefferys, DB | 1 |
| Vale, JA | 1 |
| Stimmesse, B | 1 |
| Daoudal, P | 1 |
| Neidhardt, A | 1 |
| Ory, JP | 1 |
| al-Waili, NS | 1 |
| Hasan, NU | 1 |
| Iberti, TJ | 1 |
| Zeisler, J | 1 |
| Wiggins, RC | 1 |
| Glatfelter, A | 1 |
| Campbell, AM | 1 |
| Kunkel, RG | 1 |
| Ulevitch, RJ | 1 |
| Cohen, N | 1 |
| Modai, D | 1 |
| Golik, A | 1 |
| Eshkoly, M | 1 |
| Theitler, J | 1 |
| Scapa, E | 1 |
| Gwee, MC | 1 |
| Cheah, LS | 1 |
| Choonara, IA | 1 |
| Cholerton, S | 1 |
| Haynes, BP | 1 |
| Breckenridge, AM | 1 |
| Park, BK | 1 |
| Tanner, LA | 1 |
| Arrowsmith, JB | 1 |
2 reviews available for cimetidine and Bradyarrhythmia
| Article | Year |
|---|---|
Clinical aspects of cardiovascular effects of H2-receptor antagonists.
Topics: Animals; Atrioventricular Node; Blood Pressure; Bradycardia; Cardiovascular System; Cimetidine; Elec | 1995 |
Actions of cimetidine and ranitidine at some cholinergic sites: implications in toxicology and anesthesia.
Topics: Anesthesia; Animals; Antihypertensive Agents; Bradycardia; Cholinesterase Inhibitors; Cimetidine; Co | 1986 |
1 trial available for cimetidine and Bradyarrhythmia
| Article | Year |
|---|---|
Stereoselective interaction between the R enantiomer of warfarin and cimetidine.
Topics: Administration, Oral; Bradycardia; Cimetidine; Drug Eruptions; Drug Interactions; Half-Life; Humans; | 1986 |
16 other studies available for cimetidine and Bradyarrhythmia
| Article | Year |
|---|---|
Fatal bradycardia after intentional overdose of cimetidine and diazepam.
Topics: Adult; Bradycardia; Cimetidine; Diazepam; Drug Synergism; Female; Guanidines; Humans; Suicide | 1982 |
Ranitidine and side effects.
Topics: Bradycardia; Cimetidine; Furans; Humans; Prolactin; Ranitidine | 1983 |
Atropine toxicity in acute cervical spinal injury.
Topics: Adult; Atropine; Bradycardia; Cimetidine; Hallucinations; Humans; Male; Spinal Injuries | 1984 |
Cimetidine and sinus-node function.
Topics: Animals; Bradycardia; Cimetidine; Dogs; Guanidines; Haplorhini; Heart Rate; Humans; Receptors, Hista | 1980 |
Bradycardia associated with cimetidine.
Topics: Aged; Bradycardia; Cimetidine; Gastrointestinal Hemorrhage; Guanidines; Humans; Male | 1980 |
Cimetidine, vasopressin and chronotropic incompetence.
Topics: Arrhythmias, Cardiac; Bradycardia; Cimetidine; Coronary Disease; Drug Therapy, Combination; Electroc | 1982 |
Bradycardia after cimetidine.
Topics: Bradycardia; Cimetidine; Gastrointestinal Hemorrhage; Guanidines; Humans; Male; Middle Aged | 1977 |
[Fatal cardiac arrhythmia during treatment with cimetidine].
Topics: Adult; Arrhythmias, Cardiac; Bradycardia; Cardiac Complexes, Premature; Cimetidine; Female; Guanidin | 1978 |
Cimetidine and bradycardia.
Topics: Adult; Bradycardia; Cimetidine; Guanidines; Humans; Male; Middle Aged | 1978 |
[Bradycardia during treatment with cimetidine].
Topics: Aged; Bradycardia; Cimetidine; Guanidines; Humans; Male | 1978 |
Cimetidine and bradycardia.
Topics: Adult; Bradycardia; Cimetidine; Female; Humans; Male; Middle Aged | 1992 |
Hemodynamic effects of H2-receptor antagonists.
Topics: Bradycardia; Cimetidine; Critical Care; Gastric Acid; Histamine H2 Antagonists; Humans; Hypotension; | 1990 |
Correction: Cimetidine-induced bradycardia.
Topics: Bradycardia; Cimetidine; Humans; Nitroglycerin | 1990 |
Acute hypotension due to platelet serotonin-induced chemoreflexes after intravenous injection of dextran sulfate in the rabbit.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Autonomic Nervous System; Blood Platelets; Bradyc | 1985 |
Cimetidine-related cardiac conduction disturbances and confusion.
Topics: Aged; Bradycardia; Cimetidine; Cognition Disorders; Confusion; Female; Humans; Pre-Excitation Syndro | 1989 |
Bradycardia and H2 antagonists.
Topics: Bradycardia; Cimetidine; Humans; Product Surveillance, Postmarketing; Ranitidine | 1988 |