cimetidine has been researched along with Bone Neoplasms in 5 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Bone Neoplasms: Tumors or cancer located in bone tissue or specific BONES.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Cimetidine and the antioxidant N-acetylcysteine (NAC) significantly inhibited the in vitro growth inhibition of cisplatin in cells originating from the kidney, but not in SOSN2 osteosarcoma cells." | 3.76 | Protecting cisplatin-induced nephrotoxicity with cimetidine does not affect antitumor activity. ( Katsuda, H; Katsura, H; Miyamoto, K; Nagata, N; Sai, Y; Waki, Y; Yamashita, M; Yu, J, 2010) |
| "The prognosis of advanced renal cell carcinoma, especially with metastatic lesions was very poor." | 2.67 | [Management of advanced renal cell carcinoma: surgical treatment of metastasis]. ( Kinouchi, T; Kotake, T, 1994) |
| "All patients had bone metastases." | 1.28 | Treatment of hormone-refractory stage D carcinoma of prostate with coumarin (1,2-benzopyrone) and cimetidine: a pilot study. ( Butler, K; Hermansen, D; Marshall, ME, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Katsuda, H | 1 |
| Yamashita, M | 1 |
| Katsura, H | 1 |
| Yu, J | 1 |
| Waki, Y | 1 |
| Nagata, N | 1 |
| Sai, Y | 1 |
| Miyamoto, K | 1 |
| Kinouchi, T | 2 |
| Kotake, T | 2 |
| Schmidt, H | 1 |
| Geertsen, PF | 1 |
| Fode, K | 1 |
| Rytter, C | 1 |
| Bastholt, L | 1 |
| von der Maase, H | 1 |
| Saiki, S | 1 |
| Kuroda, M | 1 |
| Miki, T | 1 |
| Kiyohara, H | 1 |
| Usami, M | 1 |
| Marshall, ME | 1 |
| Butler, K | 1 |
| Hermansen, D | 1 |
2 trials available for cimetidine and Bone Neoplasms
| Article | Year |
|---|---|
[Management of advanced renal cell carcinoma: surgical treatment of metastasis].
Topics: Adrenal Gland Neoplasms; Aged; Bone Neoplasms; Carcinoma, Renal Cell; Cimetidine; Combined Modality | 1994 |
Subcutaneous interleukin-2 and interferon-alpha plus cisplatin with and without prophylactic cimetidine in patients with metastatic malignant melanoma: a phase II study.
Topics: Adjuvants, Immunologic; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; | 2000 |
3 other studies available for cimetidine and Bone Neoplasms
| Article | Year |
|---|---|
Protecting cisplatin-induced nephrotoxicity with cimetidine does not affect antitumor activity.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Bone Neoplasms; Cell Line; Cell Line, Tumor; Cimetid | 2010 |
Treatment of metastatic renal cell carcinoma with a combination of human lymphoblastoid interferon-alpha and cimetidine.
Topics: Administration, Oral; Aged; Bone Neoplasms; Carcinoma, Renal Cell; Cimetidine; Female; Humans; Injec | 1991 |
Treatment of hormone-refractory stage D carcinoma of prostate with coumarin (1,2-benzopyrone) and cimetidine: a pilot study.
Topics: Aged; Bone Neoplasms; Cimetidine; Coumarins; Drug Therapy, Combination; Humans; Male; Middle Aged; N | 1990 |