cimetidine has been researched along with Body Weight in 31 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The pharmacokinetics and metabolism of cimetidine were studied in five cystic fibrosis patients (mean age 12." | 7.67 | The bioavailability and pharmacokinetics of cimetidine and its metabolites in juvenile cystic fibrosis patients: age related differences as compared to adults. ( Assael, BM; Padoan, R; Schentag, JJ; Ziemniak, JA, 1984) |
| "The effects of two doses orally administered Cimetidine on gastric and acid production and on intestinal absorption in 13 patients with cystic fibrosis who were treated with pancreatin supplementation were studied." | 7.66 | Cimetidine as an adjunct to oral enzymes in the treatment of malabsorption due to cystic fibrosis. ( de Biéville, F; Fernandes, J; Kerrebijn, KF; Neijens, HJ; van Caillie, M, 1981) |
| "The effectiveness and safety of the use of cimetidine as an adjunct to pancreatic enzymes was evaluated in eight patients with cystic fibrosis having pancreatic insufficiency." | 7.66 | Effectiveness of cimetidine as an adjunct to supplemental pancreatic enzymes in patients with cystic fibrosis. ( Dunn, GD; Hubbard, VS; Lester, LA, 1980) |
| "The work describes the effects of cimetidine on stress-induced gizzard erosions (Experiment A) and the influence of the long-term application (42 days) of the same drug on weight gain and feed consumption during broiler fattening (Experiment B)." | 3.70 | Effects of cimetidine on broiler fattening and on stress-induced gizzard erosion in chicken. ( Bidin, Z; Culjak, K; Dzaja, P; Grabarević, Z; Mas, N; Mazija, H; Mikulec, Z; Njari, B; Perić, J; Serman, V; Simec, Z, 1999) |
| "The pharmacokinetics and metabolism of cimetidine were studied in five cystic fibrosis patients (mean age 12." | 3.67 | The bioavailability and pharmacokinetics of cimetidine and its metabolites in juvenile cystic fibrosis patients: age related differences as compared to adults. ( Assael, BM; Padoan, R; Schentag, JJ; Ziemniak, JA, 1984) |
| " Alprazolam's pharmacokinetics may be altered by age and sex, body weight, and concurrent treatment with cimetidine." | 3.66 | Pharmacokinetics of alprazolam. ( Abernethy, DR; Divoll, M; Greenblatt, DJ; Shader, RI, 1983) |
| "The effects of two doses orally administered Cimetidine on gastric and acid production and on intestinal absorption in 13 patients with cystic fibrosis who were treated with pancreatin supplementation were studied." | 3.66 | Cimetidine as an adjunct to oral enzymes in the treatment of malabsorption due to cystic fibrosis. ( de Biéville, F; Fernandes, J; Kerrebijn, KF; Neijens, HJ; van Caillie, M, 1981) |
| "The effectiveness and safety of the use of cimetidine as an adjunct to pancreatic enzymes was evaluated in eight patients with cystic fibrosis having pancreatic insufficiency." | 3.66 | Effectiveness of cimetidine as an adjunct to supplemental pancreatic enzymes in patients with cystic fibrosis. ( Dunn, GD; Hubbard, VS; Lester, LA, 1980) |
| " Methylprednisolone sodium succinate was given at a dosage of 30 mg/kg of body weight prior to myelography, followed by a second full or half dose 2 to 4 hours later at clinician discretion." | 2.68 | Clinical evaluation of cimetidine, sucralfate, and misoprostol for prevention of gastrointestinal tract bleeding in dogs undergoing spinal surgery. ( Bostwick, DR; Hanson, SM; Smith, MO; Twedt, DC, 1997) |
| "Omeprazole is an inhibitor of gastric H+,K(+)-ATPase." | 1.29 | Effect of omeprazole, an inhibitor of H+,K(+)-ATPase, on bone resorption in humans. ( Abe, K; Furukawa, Y; Katano, K; Mizunashi, K, 1993) |
| "The dose-response and plasma concentration-response relationships of cyclosporine after both inducing and inhibiting its metabolism were studied in a mouse heart transplant model." | 1.28 | In vivo evaluation of the effects of altered cyclosporine metabolism on its immunosuppressive potency. ( Babany, G; Babany, I; Kates, RE; Morris, RE; Shepherd, S, 1989) |
| "Cimetidine was administered in the mothers' drinking water at several levels reflecting both human and rat therapeutic-like doses from day 17 of gestation through day 7 of lactation." | 1.27 | Prospective study on the sexual development of male and female rats perinatally exposed to maternally administered cimetidine. ( Babalola, GO; Bitar, MS; Hirst, SA; Shapiro, BH, 1988) |
| " According to median lethalities, all three known carcinogens were substantially more toxic than nitrosocimetidine whether administered by the intravenous, intraperitoneal, or oral routes." | 1.27 | Comparison of the acute toxicity of N-nitrosocimetidine with three structurally related carcinogens in the rat. ( Hard, GC; Jensen, DE; Magee, PN; Ogiu, T, 1986) |
| " This same dosage in obese individuals with normal serum creatinine values should result in the same average steady-state serum concentrations." | 1.27 | Cimetidine clearance in the obese. ( Bauer, LA; Dellinger, EP; Edwards, WA; Ferreri, L; Jack, R; Raisys, V; Simonowitz, D; Wareing-Tran, C, 1985) |
| "005) and a shorter elimination half-life (83 +/- 26 versus 122 +/- 16 min; P less than 0." | 1.27 | Cimetidine pharmacokinetics and dosage requirements in children. ( Becker, M; Gugler, R; Somogyi, A, 1985) |
| " The age-related increase in bioavailability of oral cimetidine, as measured by AUC, was probably due to decreased total clearance of the drug, which resulted from the opposed changes (by themselves not significant) of distribution volume towards a decrease and of half-life towards an increase with age." | 1.26 | Blood level of cimetidine in relation to age. ( Borgogelli, E; Lodola, E; Redolfi, A, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (67.74) | 18.7374 |
| 1990's | 6 (19.35) | 18.2507 |
| 2000's | 4 (12.90) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ishihara, Y | 1 |
| Sekine, M | 1 |
| Nakazawa, M | 1 |
| Shimamoto, N | 1 |
| Lesclous, P | 1 |
| Guez, D | 1 |
| Baroukh, B | 1 |
| Vignery, A | 1 |
| Saffar, JL | 1 |
| Abernethy, DR | 1 |
| Greenblatt, DJ | 1 |
| Divoll, M | 1 |
| Shader, RI | 1 |
| de la Pierre, M | 1 |
| Aricò, S | 1 |
| Capussotti, L | 1 |
| Dellepiane, M | 1 |
| Marucci, M | 1 |
| Gandini, G | 1 |
| Imarisio, P | 1 |
| Ackerman, SH | 1 |
| Shindledecker, RD | 1 |
| Ziemniak, JA | 1 |
| Assael, BM | 1 |
| Padoan, R | 1 |
| Schentag, JJ | 1 |
| de Biéville, F | 1 |
| Neijens, HJ | 1 |
| Fernandes, J | 1 |
| van Caillie, M | 1 |
| Kerrebijn, KF | 1 |
| Whelan, G | 1 |
| Ghishan, FK | 1 |
| Pierce, E | 1 |
| Garzon, B | 1 |
| Ducroc, R | 1 |
| Geloso, JP | 1 |
| Hubbard, VS | 1 |
| Dunn, GD | 1 |
| Lester, LA | 1 |
| Broulik, PD | 1 |
| Chiou, WL | 1 |
| Choi, YM | 1 |
| Mizunashi, K | 1 |
| Furukawa, Y | 1 |
| Katano, K | 1 |
| Abe, K | 1 |
| Hanson, SM | 1 |
| Bostwick, DR | 1 |
| Twedt, DC | 1 |
| Smith, MO | 1 |
| Grabarević, Z | 1 |
| Dzaja, P | 1 |
| Perić, J | 1 |
| Serman, V | 1 |
| Bidin, Z | 1 |
| Mazija, H | 1 |
| Mas, N | 1 |
| Mikulec, Z | 1 |
| Culjak, K | 1 |
| Simec, Z | 1 |
| Njari, B | 1 |
| Guaraldo, L | 1 |
| Sertiè, JA | 1 |
| Bacchi, EM | 1 |
| Caballero, F | 1 |
| Gerez, E | 1 |
| Batlle, A | 1 |
| Vazquez, E | 1 |
| Redolfi, A | 1 |
| Borgogelli, E | 1 |
| Lodola, E | 1 |
| Blum, AL | 1 |
| Bucher, P | 1 |
| Lepsien, G | 1 |
| Weber, K | 1 |
| Giger, M | 1 |
| Sonnenberg, A | 1 |
| Kamiyasu, K | 1 |
| Awata, H | 1 |
| Inoshiri, S | 1 |
| Doi, A | 1 |
| Omawari, N | 1 |
| Okegawa, T | 1 |
| Kawasaki, A | 1 |
| Shinomiya, K | 1 |
| Tanaka, M | 1 |
| Suzuki, Y | 1 |
| Wyatt, CL | 1 |
| Jensen, LS | 1 |
| Rowland, GN | 1 |
| Babany, G | 1 |
| Morris, RE | 1 |
| Babany, I | 1 |
| Shepherd, S | 1 |
| Kates, RE | 1 |
| Shapiro, BH | 1 |
| Hirst, SA | 1 |
| Babalola, GO | 1 |
| Bitar, MS | 1 |
| Pinelli, A | 1 |
| Trivulzio, S | 1 |
| Campion, EW | 1 |
| Avorn, J | 1 |
| Reder, VA | 1 |
| Olins, NJ | 1 |
| Goldman, CD | 1 |
| Rudloff, MA | 1 |
| Ternberg, JL | 1 |
| Ogiu, T | 1 |
| Hard, GC | 1 |
| Magee, PN | 1 |
| Jensen, DE | 1 |
| Bauer, LA | 1 |
| Wareing-Tran, C | 1 |
| Edwards, WA | 1 |
| Raisys, V | 1 |
| Ferreri, L | 1 |
| Jack, R | 1 |
| Dellinger, EP | 1 |
| Simonowitz, D | 1 |
| Anderson, LM | 1 |
| Giner-Sorolla, A | 1 |
| Haller, IM | 1 |
| Budinger, JM | 1 |
| Somogyi, A | 1 |
| Becker, M | 1 |
| Gugler, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Correlation Between Peri-implantitis and Assumptions of Medications: a Retrospective Study[NCT04783974] | 270 participants (Actual) | Observational | 2021-02-15 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for cimetidine and Body Weight
| Article | Year |
|---|---|
Clinical evaluation of cimetidine, sucralfate, and misoprostol for prevention of gastrointestinal tract bleeding in dogs undergoing spinal surgery.
Topics: Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Blood Loss, Surgical; | 1997 |
30 other studies available for cimetidine and Body Weight
| Article | Year |
|---|---|
Suppression of myocardial ischemia-reperfusion injury by inhibitors of cytochrome P450 in rats.
Topics: Animals; Body Weight; Cimetidine; Coronary Vessels; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhib | 2009 |
Histamine participates in the early phase of trabecular bone loss in ovariectomized rats.
Topics: Animals; Body Weight; Bone Resorption; Cimetidine; Famotidine; Female; Femur; Histamine; Immunohisto | 2004 |
Pharmacokinetics of alprazolam.
Topics: Age Factors; Alprazolam; Anti-Anxiety Agents; Benzodiazepines; Biotransformation; Body Weight; Cimet | 1983 |
[Description of a case of Zollinger-Ellison syndrome].
Topics: Benzodiazepinones; Body Weight; Cimetidine; Diarrhea; Female; Gastrectomy; Gastric Acid; Humans; Mid | 1984 |
Maturational increases and decreases in acid secretion in the rat.
Topics: Acids; Animals; Basal Metabolism; Body Weight; Cimetidine; Ligation; Male; Pylorus; Rats | 1984 |
The bioavailability and pharmacokinetics of cimetidine and its metabolites in juvenile cystic fibrosis patients: age related differences as compared to adults.
Topics: Administration, Oral; Adolescent; Adult; Aging; Biological Availability; Biotransformation; Body Sur | 1984 |
Cimetidine as an adjunct to oral enzymes in the treatment of malabsorption due to cystic fibrosis.
Topics: Administration, Oral; Adolescent; Body Weight; Celiac Disease; Child; Cimetidine; Cystic Fibrosis; D | 1981 |
Management of gastro-oesophageal reflux.
Topics: Antacids; Body Weight; Cimetidine; Diagnosis, Differential; Diet, Reducing; Esophagoscopy; Gastroeso | 1982 |
Placental calcium transport: effect of cimetidine.
Topics: Animals; Biological Transport, Active; Body Weight; Calcium; Calcium Radioisotopes; Cimetidine; Fema | 1982 |
Ontogenesis of gastric response to agonists and antagonists of acid secretion in fetal rat.
Topics: Acetylcholine; Animals; Body Weight; Cimetidine; Deoxyglucose; Female; Fetus; Gastric Acid; Histamin | 1982 |
Effectiveness of cimetidine as an adjunct to supplemental pancreatic enzymes in patients with cystic fibrosis.
Topics: Adolescent; Adult; Body Weight; Celiac Disease; Child; Cimetidine; Cystic Fibrosis; Drug Therapy, Co | 1980 |
Antiandrogenic effect of cimetidine in mice.
Topics: Adrenal Glands; Androgen Antagonists; Animals; Body Weight; Cimetidine; Guanidines; Kidney; Male; Mi | 1980 |
Unbound total (plasma) clearance approach in interspecies pharmacokinetics correlation: theophylline-cimetidine interaction.
Topics: Animals; Blood Proteins; Body Weight; Cimetidine; Dogs; Drug Interactions; Humans; Metabolic Clearan | 1995 |
Effect of omeprazole, an inhibitor of H+,K(+)-ATPase, on bone resorption in humans.
Topics: Adolescent; Adult; Aged; Alkaline Phosphatase; Biomarkers; Body Weight; Bone Resorption; Calcium; Ch | 1993 |
Effects of cimetidine on broiler fattening and on stress-induced gizzard erosion in chicken.
Topics: Animals; Body Weight; Bursa of Fabricius; Chickens; Cimetidine; Female; Gizzard, Avian; Histamine H2 | 1999 |
Antiulcer action of the hydroalcoholic extract and fractions of Davilla rugosa Poiret in the rat.
Topics: Acetic Acid; Analysis of Variance; Animals; Anti-Ulcer Agents; Body Weight; Brazil; Cimetidine; Etha | 2001 |
Interaction of cimetidine with P450 in a mouse model of hepatocarcinogenesis initiation.
Topics: 5-Aminolevulinate Synthetase; Animals; Body Weight; Carcinogens; Catalase; Cimetidine; Cytochrome P- | 2002 |
Blood level of cimetidine in relation to age.
Topics: Adult; Aged; Aging; Blood Urea Nitrogen; Body Weight; Cimetidine; Creatinine; Female; Guanidines; Ha | 1979 |
[Treatment of reflux disease (author's transl)].
Topics: Alginates; Antacids; Body Weight; Cimetidine; Esophagitis; Gastroesophageal Reflux; Humans; Metoclop | 1978 |
[Effects of FOY-305 on post-operative reflux esophagitis in rats (I). Effects of FOY-305 on reflux esophagitis after total gastrectomy in rats].
Topics: Alginates; Animals; Body Weight; Cimetidine; Disease Models, Animal; Esophagitis, Peptic; Esters; Ga | 1991 |
Effect of cimetidine on eggshell quality and plasma 25-hydroxycholecalciferol in laying hens.
Topics: Animal Feed; Animals; Body Weight; Calcifediol; Calcium; Chickens; Cholecalciferol; Cimetidine; Eati | 1990 |
In vivo evaluation of the effects of altered cyclosporine metabolism on its immunosuppressive potency.
Topics: Animals; Body Weight; Cimetidine; Cyclosporins; Cytochrome P-450 Enzyme System; Dose-Response Relati | 1989 |
Prospective study on the sexual development of male and female rats perinatally exposed to maternally administered cimetidine.
Topics: Androgens; Animals; Body Weight; Cimetidine; Estrus; Female; Male; Orchiectomy; Organ Size; Perinato | 1988 |
Antiprostatic effect associated with zinc depletion in cimetidine-treated rats.
Topics: Animals; Body Weight; Cimetidine; Male; Organ Size; Prostate; Rats; Rats, Inbred Strains; Zinc | 1988 |
Overmedication of the low-weight elderly.
Topics: Adult; Age Factors; Aged; Body Weight; Cimetidine; Digoxin; Drug Prescriptions; Flurazepam; Humans; | 1987 |
Cimetidine and neonatal small bowel adaptation: an experimental study.
Topics: Adaptation, Physiological; Animals; Body Weight; Cimetidine; Ileum; Intestine, Small; Jejunum; Malab | 1987 |
Comparison of the acute toxicity of N-nitrosocimetidine with three structurally related carcinogens in the rat.
Topics: Administration, Oral; Animals; Body Weight; Cimetidine; Female; Methylnitronitrosoguanidine; Methyln | 1986 |
Cimetidine clearance in the obese.
Topics: Adult; Body Weight; Cimetidine; Creatinine; Female; Half-Life; Humans; Infusions, Parenteral; Kineti | 1985 |
Effects of cimetidine, nitrite, cimetidine plus nitrite, and nitrosocimetidine on tumors in mice following transplacental plus chronic lifetime exposure.
Topics: Animals; Body Weight; Cimetidine; Dose-Response Relationship, Drug; Female; Fetus; Lung Neoplasms; M | 1985 |
Cimetidine pharmacokinetics and dosage requirements in children.
Topics: Administration, Oral; Adolescent; Adult; Body Weight; Child; Child, Preschool; Cimetidine; Female; H | 1985 |