cimetidine has been researched along with Blood Pressure, High in 17 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Aliskiren is the first in a new class of orally effective direct renin inhibitors approved for the treatment of hypertension." | 5.13 | A study of the pharmacokinetic interactions of the direct renin inhibitor aliskiren with allopurinol, celecoxib and cimetidine in healthy subjects. ( Ayalasomayajula, S; Bizot, MN; Dieterich, HA; Dole, WP; Howard, D; Tchaloyan, S; Yeh, CM, 2008) |
| "Aliskiren is the first in a new class of orally effective renin inhibitors for the treatment of hypertension." | 5.11 | Pharmacokinetic interactions of the oral renin inhibitor aliskiren with lovastatin, atenolol, celecoxib and cimetidine. ( Corynen, S; Dieterle, W; Mann, J; Vaidyanathan, S, 2005) |
| " for 6 days) on the pharmacokinetics and pharmacodynamic effects of the angiotensin II receptor antagonist, losartan (100 mg)." | 2.68 | Effects of cimetidine on pharmacokinetics and pharmacodynamics of losartan, an AT1-selective non-peptide angiotensin II receptor antagonist. ( Bradstreet, TE; Goldberg, MR; Höglund, P; Lo, MW; Ritter, MA, 1995) |
| " The interaction of nifedipine and cimetidine is thus of clinical significance because of its pharmacodynamic effect." | 2.65 | [Effect of cimetidine and ranitidine on the pharmacokinetics and anti-hypertensive effect of nifedipine]. ( Heidemann, H; Janisch, HD; Kirch, W; Ohnhaus, EE; Rämsch, K, 1983) |
| "2 Caffeine (300 mg) was given orally before any treatment and at the beginning of the last day of each treatment course." | 2.65 | Decreased systemic clearance of caffeine due to cimetidine. ( Broughton, LJ; Rogers, HJ, 1981) |
| " Coexisting disease states, such as renal or hepatic dysfunction, may require individualized dosing of these agents." | 2.37 | Individualization of calcium entry-blocker dosage for systemic hypertension. ( Piepho, RW, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (47.06) | 18.7374 |
| 1990's | 5 (29.41) | 18.2507 |
| 2000's | 3 (17.65) | 29.6817 |
| 2010's | 1 (5.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kihara, K | 1 |
| Kamimura, H | 1 |
| Isayama, H | 1 |
| Fujii, Y | 1 |
| Iino, Y | 1 |
| Dieterle, W | 1 |
| Corynen, S | 1 |
| Vaidyanathan, S | 1 |
| Mann, J | 1 |
| Hannaway, PJ | 1 |
| Ayalasomayajula, S | 1 |
| Tchaloyan, S | 1 |
| Yeh, CM | 1 |
| Bizot, MN | 1 |
| Dieterich, HA | 1 |
| Howard, D | 1 |
| Dole, WP | 1 |
| Atkinson, AB | 1 |
| Brown, JJ | 1 |
| Lever, AF | 1 |
| McAreavey, D | 1 |
| Robertson, JI | 1 |
| Behan, PO | 1 |
| Melville, ID | 1 |
| Weir, AI | 1 |
| Dadkar, NK | 1 |
| Aroskar, VA | 1 |
| Gupte, RD | 1 |
| Dohadwalla, AN | 1 |
| Kirch, W | 1 |
| Janisch, HD | 1 |
| Heidemann, H | 1 |
| Rämsch, K | 1 |
| Ohnhaus, EE | 1 |
| Klimenko, VS | 1 |
| Osipov, SG | 1 |
| Masenko, VP | 1 |
| Titov, VN | 1 |
| Broughton, LJ | 1 |
| Rogers, HJ | 1 |
| Salive, ME | 1 |
| Jones, CA | 1 |
| Guralnik, JM | 1 |
| Agodoa, LY | 1 |
| Pahor, M | 1 |
| Wallace, RB | 1 |
| Goldberg, MR | 1 |
| Lo, MW | 1 |
| Bradstreet, TE | 1 |
| Ritter, MA | 1 |
| Höglund, P | 1 |
| Lada, W | 1 |
| Jones, FA | 1 |
| Hunt, T | 1 |
| Baraka, A | 1 |
| Nauphal, M | 1 |
| Arab, W | 1 |
| Shane, E | 1 |
| Barrett, RJ | 1 |
| Kau, ST | 1 |
| Piepho, RW | 1 |
4 reviews available for cimetidine and Blood Pressure, High
| Article | Year |
|---|---|
[Diagnostic value of a study of beta 2-microglobulin in the blood serum and urine].
Topics: Aminoglycosides; Anti-Bacterial Agents; beta 2-Microglobulin; Cimetidine; Creatinine; Diabetic Nephr | 1984 |
[Imidazoline receptors and use of drug blocking receptors I1].
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Antihypertensive Agents; Arrhythmias, Cardi | 1996 |
Medical management of asymptomatic primary hyperparathyroidism.
Topics: Administration, Oral; Calcium; Calcium, Dietary; Cimetidine; Diphosphonates; Diuretics; Humans; Hype | 1991 |
Individualization of calcium entry-blocker dosage for systemic hypertension.
Topics: Adult; Age Factors; Aged; Calcium Channel Blockers; Child; Cimetidine; Diabetes Complications; Digox | 1985 |
5 trials available for cimetidine and Blood Pressure, High
| Article | Year |
|---|---|
Pharmacokinetic interactions of the oral renin inhibitor aliskiren with lovastatin, atenolol, celecoxib and cimetidine.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Amides; Atenolol; Celecoxib; Cimetidine; Cross-Over | 2005 |
A study of the pharmacokinetic interactions of the direct renin inhibitor aliskiren with allopurinol, celecoxib and cimetidine in healthy subjects.
Topics: Adolescent; Adult; Allopurinol; Amides; Antihypertensive Agents; Celecoxib; Cimetidine; Cyclooxygena | 2008 |
[Effect of cimetidine and ranitidine on the pharmacokinetics and anti-hypertensive effect of nifedipine].
Topics: Adult; Blood Pressure; Cimetidine; Clinical Trials as Topic; Drug Administration Schedule; Drug Inte | 1983 |
Decreased systemic clearance of caffeine due to cimetidine.
Topics: Adult; Biological Availability; Caffeine; Cimetidine; Drug Interactions; Female; Guanidines; Humans; | 1981 |
Effects of cimetidine on pharmacokinetics and pharmacodynamics of losartan, an AT1-selective non-peptide angiotensin II receptor antagonist.
Topics: Adult; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Cimetidine; Cr | 1995 |
8 other studies available for cimetidine and Blood Pressure, High
| Article | Year |
|---|---|
[Suppression of renin-angiotensin system and cancer therapy (discussion)].
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; B | 2010 |
Emergency department treatment of anaphylaxis: is epinephrine always indicated?
Topics: Aged; Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Cimetidine; Contraindications; Diphenhyd | 2006 |
Neurological dysfunction in two patients receiving captopril and cimetidine.
Topics: Captopril; Cimetidine; Female; Guanidines; Humans; Hypertension; Male; Middle Aged; Peripheral Nervo | 1980 |
Central pressor activity of cimetidine in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Brain; Cimetidine; Hydroxydopamines; Hypertension; Male; Norepinephrine; Ox | 1984 |
Serum creatinine levels in older adults: relationship with health status and medications.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Black People; Cardiovascular Agents; Cimetidine | 1995 |
Drugs for peptic ulcer.
Topics: Aged; Body Fluids; Carbenoxolone; Cimetidine; Female; Glycyrrhetinic Acid; Guanidines; Humans; Hyper | 1979 |
Cimetidine-dobutamine interaction?
Topics: Anesthesia, Intravenous; Cimetidine; Coronary Artery Bypass; Dobutamine; Drug Interactions; Humans; | 1992 |
Myocardial and vascular actions of amiloride in spontaneously hypertensive rats.
Topics: Amiloride; Animals; Atropine; Blood Pressure; Cardiovascular System; Cimetidine; Dose-Response Relat | 1986 |