cimetidine has been researched along with Blood Poisoning in 9 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
| Excerpt | Relevance | Reference |
|---|---|---|
| "12 patients of an intensive care unit on respirator with peritonitis respectively septic complications were treated with 300 mg/die Ranitidine or 2000 mg Cimetidine/die administered via perfusor infusion under the conditions of a randomized double blind study." | 9.05 | [Control of the intragastric pH value in infection and peritonitis by ranitidine versus cimetidine. A double-blind study]. ( Hölscher, AH; Ketterl, R; Siewert, JR; Weiser, HF, 1984) |
| " Gastric pH was monitored hourly and the dosage of medication adjusted as required to maintain gastric pH above 4." | 6.65 | Failure of gastric pH control by antacids or cimetidine in the critically ill: a valid sign of sepsis. ( Martin, LF; Max, MH; Polk, HC, 1980) |
| "12 patients of an intensive care unit on respirator with peritonitis respectively septic complications were treated with 300 mg/die Ranitidine or 2000 mg Cimetidine/die administered via perfusor infusion under the conditions of a randomized double blind study." | 5.05 | [Control of the intragastric pH value in infection and peritonitis by ranitidine versus cimetidine. A double-blind study]. ( Hölscher, AH; Ketterl, R; Siewert, JR; Weiser, HF, 1984) |
| "Cyclo-oxygenase inhibition (with ibuprofen) combined with histamine (H1, H2) receptor antagonism (with diphenhydramine and cimetidine) attenuates microvascular leak injury in sepsis syndromes." | 3.69 | Multi-agent therapy in the treatment of sepsis-induced microvascular injury. ( Carey, PD; Fowler, AA; Sugerman, HJ; Walsh, CJ; Windsor, AC, 1994) |
| "Critically ill trauma patients were entered in a prospective, randomized trial to determine the role of gastric colonization in the development of pneumonia." | 2.67 | Role of gastric colonization in the development of pneumonia in critically ill trauma patients: results of a prospective randomized trial. ( Burchard, KW; DeMaria, E; McDonald, L; Peterson, D; Robinson, A; Simms, HH, 1991) |
| " Gastric pH was monitored hourly and the dosage of medication adjusted as required to maintain gastric pH above 4." | 2.65 | Failure of gastric pH control by antacids or cimetidine in the critically ill: a valid sign of sepsis. ( Martin, LF; Max, MH; Polk, HC, 1980) |
| "Especially patients with severe sepsis or septic shock are prone to develop lesions of the upper gastrointestinal tract with consecutive bleeding." | 1.35 | [Stress ulcer prophylaxis in septic patients. Evidence-based overview]. ( Elke, G; Schädler, D; Scholz, J; Weiler, N; Zick, G, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (66.67) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Elke, G | 1 |
| Schädler, D | 1 |
| Zick, G | 1 |
| Scholz, J | 1 |
| Weiler, N | 1 |
| Ketterl, R | 1 |
| Hölscher, AH | 1 |
| Weiser, HF | 1 |
| Siewert, JR | 1 |
| Hillman, KM | 1 |
| Martin, LF | 1 |
| Max, MH | 1 |
| Polk, HC | 1 |
| Carey, PD | 1 |
| Windsor, AC | 1 |
| Walsh, CJ | 1 |
| Fowler, AA | 1 |
| Sugerman, HJ | 1 |
| Belliveau, P | 1 |
| Vas, S | 1 |
| Himal, HS | 1 |
| Simms, HH | 1 |
| DeMaria, E | 1 |
| McDonald, L | 1 |
| Peterson, D | 1 |
| Robinson, A | 1 |
| Burchard, KW | 1 |
| Garvey, BM | 1 |
| McCambley, JA | 1 |
| Tuxen, DV | 1 |
| Ho, JL | 1 |
| Shands, KN | 1 |
| Friedland, G | 1 |
| Eckind, P | 1 |
| Fraser, DW | 1 |
3 trials available for cimetidine and Blood Poisoning
| Article | Year |
|---|---|
[Control of the intragastric pH value in infection and peritonitis by ranitidine versus cimetidine. A double-blind study].
Topics: Abscess; Adolescent; Adult; Aged; Cimetidine; Clinical Trials as Topic; Critical Care; Double-Blind | 1984 |
Failure of gastric pH control by antacids or cimetidine in the critically ill: a valid sign of sepsis.
Topics: Adolescent; Adult; Antacids; Cimetidine; Critical Care; Female; Gastric Juice; Gastritis; Gastrointe | 1980 |
Role of gastric colonization in the development of pneumonia in critically ill trauma patients: results of a prospective randomized trial.
Topics: Adolescent; Adult; Antacids; Bacteria; Cimetidine; Cross Infection; Gastric Juice; Humans; Hydrogen- | 1991 |
6 other studies available for cimetidine and Blood Poisoning
| Article | Year |
|---|---|
[Stress ulcer prophylaxis in septic patients. Evidence-based overview].
Topics: Anti-Ulcer Agents; Cimetidine; Duodenal Ulcer; Evidence-Based Medicine; Gastric Acid; Gastrointestin | 2008 |
Colonisation of the gastric contents in critically ill patients.
Topics: Cimetidine; Critical Care; Cross Infection; Gastric Acidity Determination; Gastric Mucosa; Humans; S | 1983 |
Multi-agent therapy in the treatment of sepsis-induced microvascular injury.
Topics: Animals; Cell Membrane Permeability; Cimetidine; Diphenhydramine; Hemodynamics; Hypochlorous Acid; I | 1994 |
Septic induced acute gastric erosions: the role of cimetidine.
Topics: Animals; Bacteroides fragilis; Cimetidine; Disease Models, Animal; Dogs; Enterococcus faecalis; Guan | 1978 |
Effects of gastric alkalization on bacterial colonization in critically ill patients.
Topics: Adult; Aged; Antacids; Anti-Bacterial Agents; Bacterial Physiological Phenomena; Cimetidine; Critica | 1989 |
An outbreak of type 4b Listeria monocytogenes infection involving patients from eight Boston hospitals.
Topics: Aged; Antacids; Boston; Cimetidine; Cross Infection; Disease Outbreaks; Epidemiologic Methods; Femal | 1986 |