cimetidine has been researched along with Bleeding in 9 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study, cimetidine was used to treat patients with hemophilia A and inhibitors to factor VIII who presented with acute hemorrhages (Group A) and those without hemorrhages (Group B)." | 9.08 | Treatment of patients with hemophilia A and inhibitors to factor FVIII with cimetidine. ( Ambriz Fernandez, R; Collazo Jaloma, J; Dominguez Garcia, V; Martinez Murillo, C; Quintana Gonzalez, S; Rodriguez Moyado, H, 1996) |
| "Gastroesophageal reflux (GER) is a common episode in pediatric patients with severe motor and intellectual disabilities (SMID) and occasionally leads to a severe clinical state accompanied with nausea, hematemesis, melena, wheezing, pneumonia, anemia and/or failure to thrive." | 5.32 | Treatment of gastric hemorrhage by pulverized omeprazole and antacid--concomitant administration via a nasogastric tube. ( Kinoshita, E; Mukai, S; Ohtani, H; Sawada, Y; Yamaguchi, T, 2004) |
| "In this study, cimetidine was used to treat patients with hemophilia A and inhibitors to factor VIII who presented with acute hemorrhages (Group A) and those without hemorrhages (Group B)." | 5.08 | Treatment of patients with hemophilia A and inhibitors to factor FVIII with cimetidine. ( Ambriz Fernandez, R; Collazo Jaloma, J; Dominguez Garcia, V; Martinez Murillo, C; Quintana Gonzalez, S; Rodriguez Moyado, H, 1996) |
| " In a thromboplastin-induced thromboembolism model, administration of 30 mg/kg YM-75466 or 3 mg/kg warfarin significantly improved the lethality ratio." | 3.70 | Comparison of the anticoagulant and antithrombotic effects of YM-75466, a novel orally-active factor Xa inhibitor, and warfarin in mice. ( Hirayama, F; Iizumi, Y; Kawasaki, T; Koshio, H; Matsumoto, Y; Sato, K; Taniuchi, Y, 1998) |
| "We investigated the mechanisms by which 16,16-dimethyl prostaglandin E2 and histamine induced pancreatic hemorrhage in an experimental model of acute pancreatitis in cats." | 3.67 | Vasoactive drugs, microvascular permeability, and hemorrhagic pancreatitis in cats. ( Harvey, MH; Reber, HA; Wedgwood, KR, 1987) |
| ", which doses do not inhibit the gastric basal secretion nor the maximal secretory response to pentagastrin stimulation, each prevented the gastric microbleeding produced by the oral application of indomethacin." | 3.67 | Evidence of the gastric cytoprotective effects of vitamin A, atropine and cimetidine on the development of gastric mucosal damage produced by administration of indomethacin in healthy subjects. ( Jávor, T; Morón, F; Mózsik, G; Nagy, L; Ruzsa, CS; Tárnok, F, 1986) |
| "Gastroesophageal reflux (GER) is a common episode in pediatric patients with severe motor and intellectual disabilities (SMID) and occasionally leads to a severe clinical state accompanied with nausea, hematemesis, melena, wheezing, pneumonia, anemia and/or failure to thrive." | 1.32 | Treatment of gastric hemorrhage by pulverized omeprazole and antacid--concomitant administration via a nasogastric tube. ( Kinoshita, E; Mukai, S; Ohtani, H; Sawada, Y; Yamaguchi, T, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (55.56) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yamaguchi, T | 1 |
| Mukai, S | 1 |
| Kinoshita, E | 1 |
| Ohtani, H | 1 |
| Sawada, Y | 1 |
| Masciariello, S | 1 |
| Santini, M | 1 |
| Casucci, R | 1 |
| Sodo, M | 1 |
| Aprea, G | 1 |
| Sainz Samitier, R | 1 |
| Bajador Andréu, E | 1 |
| Villarón Rico, C | 1 |
| Giménez Martínez, A | 1 |
| Bueno Gómez, J | 1 |
| Ewe, K | 1 |
| Ambriz Fernandez, R | 1 |
| Quintana Gonzalez, S | 1 |
| Martinez Murillo, C | 1 |
| Dominguez Garcia, V | 1 |
| Rodriguez Moyado, H | 1 |
| Collazo Jaloma, J | 1 |
| Sato, K | 1 |
| Taniuchi, Y | 1 |
| Kawasaki, T | 1 |
| Hirayama, F | 1 |
| Koshio, H | 1 |
| Matsumoto, Y | 1 |
| Iizumi, Y | 1 |
| Launbjerg, J | 1 |
| Egeblad, H | 1 |
| Heaf, J | 1 |
| Nielsen, NH | 1 |
| Fugleholm, AM | 1 |
| Ladefoged, K | 1 |
| Harvey, MH | 1 |
| Wedgwood, KR | 1 |
| Reber, HA | 1 |
| Mózsik, G | 1 |
| Morón, F | 1 |
| Nagy, L | 1 |
| Ruzsa, CS | 1 |
| Tárnok, F | 1 |
| Jávor, T | 1 |
1 trial available for cimetidine and Bleeding
| Article | Year |
|---|---|
Treatment of patients with hemophilia A and inhibitors to factor FVIII with cimetidine.
Topics: Adjuvants, Immunologic; Adolescent; Adult; Antibodies; Child; Cimetidine; Factor VIII; Hemophilia A; | 1996 |
8 other studies available for cimetidine and Bleeding
| Article | Year |
|---|---|
Treatment of gastric hemorrhage by pulverized omeprazole and antacid--concomitant administration via a nasogastric tube.
Topics: Adolescent; Antacids; Anti-Ulcer Agents; Cimetidine; Drug Therapy, Combination; Gastroesophageal Ref | 2004 |
[Recent developments in the medical treatment of emergency cirrhotic hemorrhage. Vasopressin and glipressin, prostaglandins, somatostatin, propranolol, cimetidine and ranitidine].
Topics: Cimetidine; Emergencies; Hemorrhage; Humans; Liver Cirrhosis; Lypressin; Propranolol; Prostaglandins | 1983 |
[Development of upper digestive hemorrhage and cimetidine: prospective study].
Topics: Adolescent; Adult; Aged; Antacids; Cimetidine; Drug Therapy, Combination; Esophageal Diseases; Femal | 1982 |
[Preventive measures in gastroenterology].
Topics: Cimetidine; Colonic Neoplasms; Diarrhea; Doxycycline; Esophageal and Gastric Varices; Gastrointestin | 1981 |
Comparison of the anticoagulant and antithrombotic effects of YM-75466, a novel orally-active factor Xa inhibitor, and warfarin in mice.
Topics: Administration, Oral; Analgesics, Non-Narcotic; Animals; Anti-Bacterial Agents; Anticoagulants; Anti | 1998 |
Bleeding complications to oral anticoagulant therapy: multivariate analysis of 1010 treatment years in 551 outpatients.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Ambulatory Care; Anticoagulants; Cimetidine | 1991 |
Vasoactive drugs, microvascular permeability, and hemorrhagic pancreatitis in cats.
Topics: Animals; Capillary Permeability; Cats; Cimetidine; Drug Synergism; Female; Hemorrhage; Histamine; In | 1987 |
Evidence of the gastric cytoprotective effects of vitamin A, atropine and cimetidine on the development of gastric mucosal damage produced by administration of indomethacin in healthy subjects.
Topics: Atropine; Cimetidine; Dose-Response Relationship, Drug; Gastric Juice; Gastric Mucosa; Hemorrhage; H | 1986 |