cimetidine has been researched along with Bladder Pain Syndrome in 7 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether oral cimetidine, which reportedly improves symptoms in 60-70% of patients with painful bladder syndrome/interstitial cystitis has a similar mechanism of action on the human bladder and involving a similar peptidergic pathway as it has in human stomach, where it alters histamine-gastrin reactions mediated via H2 receptors and a proton pump." | 7.71 | Cimetidine in painful bladder syndrome: a histopathological study. ( Blackford, HN; Dasgupta, P; Dennis, P; Sharma, SD; Womack, C, 2001) |
| "To determine whether oral cimetidine, which reportedly improves symptoms in 60-70% of patients with painful bladder syndrome/interstitial cystitis has a similar mechanism of action on the human bladder and involving a similar peptidergic pathway as it has in human stomach, where it alters histamine-gastrin reactions mediated via H2 receptors and a proton pump." | 3.71 | Cimetidine in painful bladder syndrome: a histopathological study. ( Blackford, HN; Dasgupta, P; Dennis, P; Sharma, SD; Womack, C, 2001) |
| "Interstitial cystitis (IC) and bladder pain syndrome (BPS) are chronic conditions that can be debilitating for patients." | 2.58 | An evaluation of the pharmacotherapy for interstitial cystitis. ( Giusto, LL; Shoskes, DA; Zahner, PM, 2018) |
| "The typical patient with interstitial cystitis (IC) is symptomatic for many years and consults multiple physicians before IC is diagnosed." | 2.44 | [Interstitial cystitis in 2008]. ( Mouracade, P; Saussine, C, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (71.43) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Giusto, LL | 1 |
| Zahner, PM | 1 |
| Shoskes, DA | 1 |
| Dancel, R | 1 |
| Mounsey, A | 1 |
| Handler, L | 1 |
| Mouracade, P | 1 |
| Saussine, C | 1 |
| Sea, J | 1 |
| Teichman, JM | 1 |
| Tincello, DG | 1 |
| Walker, AC | 1 |
| Lewi, H | 1 |
| Dasgupta, P | 1 |
| Sharma, SD | 1 |
| Womack, C | 1 |
| Blackford, HN | 1 |
| Dennis, P | 1 |
3 reviews available for cimetidine and Bladder Pain Syndrome
| Article | Year |
|---|---|
An evaluation of the pharmacotherapy for interstitial cystitis.
Topics: Amitriptyline; Antibodies, Monoclonal; Antidepressive Agents, Tricyclic; Cimetidine; Cystitis, Inter | 2018 |
[Interstitial cystitis in 2008].
Topics: Adolescent; Adult; Algorithms; Anti-Ulcer Agents; Biopsy; Cimetidine; Cyclosporins; Cystectomy; Cyst | 2008 |
Paediatric painful bladder syndrome/interstitial cystitis: diagnosis and treatment.
Topics: Administration, Intravesical; Amitriptyline; Child; Cimetidine; Cystitis, Interstitial; Diet Therapy | 2009 |
4 other studies available for cimetidine and Bladder Pain Syndrome
| Article | Year |
|---|---|
Medications for treatment of interstitial cystitis.
Topics: Adult; Amitriptyline; Cimetidine; Cystitis, Interstitial; Evidence-Based Medicine; Female; Humans; H | 2015 |
Interstitial cystitis in the UK: results of a questionnaire survey of members of the Interstitial Cystitis Support Group.
Topics: Anticonvulsants; Cimetidine; Cystitis, Interstitial; Depression; Dimethyl Sulfoxide; Female; Histami | 2005 |
Medical therapy in interstitial cystitis: the essex experience.
Topics: Administration, Oral; Cimetidine; Cystitis, Interstitial; Drug Therapy, Combination; Histamine H2 An | 2001 |
Cimetidine in painful bladder syndrome: a histopathological study.
Topics: Cimetidine; Cystitis, Interstitial; Female; Follow-Up Studies; Histamine H2 Antagonists; Humans; Mal | 2001 |