cimetidine has been researched along with Bladder Diseases in 4 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the efficacy of oral cimetidine as a treatment for painful bladder disease (PBD, variously described as a 'symptom complex' of suprapubic pain, frequency, dysuria and nocturia in the absence of overt urine infection) by assessing symptom relief and histological changes in the bladder wall tissue components, compared with placebo." | 9.09 | Oral cimetidine gives effective symptom relief in painful bladder disease: a prospective, randomized, double-blind placebo-controlled trial. ( Thilagarajah, R; Walker, MM; Witherow, RO, 2001) |
| "To determine whether oral cimetidine, which reportedly improves symptoms in 60-70% of patients with painful bladder syndrome/interstitial cystitis has a similar mechanism of action on the human bladder and involving a similar peptidergic pathway as it has in human stomach, where it alters histamine-gastrin reactions mediated via H2 receptors and a proton pump." | 7.71 | Cimetidine in painful bladder syndrome: a histopathological study. ( Blackford, HN; Dasgupta, P; Dennis, P; Sharma, SD; Womack, C, 2001) |
| "To evaluate the efficacy of oral cimetidine as a treatment for painful bladder disease (PBD, variously described as a 'symptom complex' of suprapubic pain, frequency, dysuria and nocturia in the absence of overt urine infection) by assessing symptom relief and histological changes in the bladder wall tissue components, compared with placebo." | 5.09 | Oral cimetidine gives effective symptom relief in painful bladder disease: a prospective, randomized, double-blind placebo-controlled trial. ( Thilagarajah, R; Walker, MM; Witherow, RO, 2001) |
| "To determine whether oral cimetidine, which reportedly improves symptoms in 60-70% of patients with painful bladder syndrome/interstitial cystitis has a similar mechanism of action on the human bladder and involving a similar peptidergic pathway as it has in human stomach, where it alters histamine-gastrin reactions mediated via H2 receptors and a proton pump." | 3.71 | Cimetidine in painful bladder syndrome: a histopathological study. ( Blackford, HN; Dasgupta, P; Dennis, P; Sharma, SD; Womack, C, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Caremel, R | 1 |
| Cornu, JN | 1 |
| Kerdraon, J | 1 |
| Castel-Lacanal, E | 1 |
| Bastide, C | 1 |
| Bruyere, F | 1 |
| Guy, L | 1 |
| Karsenty, G | 1 |
| Thilagarajah, R | 1 |
| Witherow, RO | 1 |
| Walker, MM | 1 |
| Dasgupta, P | 1 |
| Sharma, SD | 1 |
| Womack, C | 1 |
| Blackford, HN | 1 |
| Dennis, P | 1 |
| Haq, A | 1 |
| Donaldson, PJ | 1 |
| Parry, JR | 1 |
1 review available for cimetidine and Bladder Diseases
| Article | Year |
|---|---|
[Drug therapy of bladder dysfunction].
Topics: Acetanilides; Anti-Inflammatory Agents; Botulinum Toxins, Type A; Cholinergic Antagonists; Cimetidin | 2013 |
1 trial available for cimetidine and Bladder Diseases
| Article | Year |
|---|---|
Oral cimetidine gives effective symptom relief in painful bladder disease: a prospective, randomized, double-blind placebo-controlled trial.
Topics: Administration, Oral; Adult; Aged; Analgesics, Non-Narcotic; Biopsy; Cimetidine; Double-Blind Method | 2001 |
2 other studies available for cimetidine and Bladder Diseases
| Article | Year |
|---|---|
Cimetidine in painful bladder syndrome: a histopathological study.
Topics: Cimetidine; Cystitis, Interstitial; Female; Follow-Up Studies; Histamine H2 Antagonists; Humans; Mal | 2001 |
Oral cimetidine gives effective symptom relief in painful bladder disease: a prospective, randomized, double-blind placebo-controlled trial.
Topics: Administration, Oral; Analgesics, Non-Narcotic; Cimetidine; Double-Blind Method; Humans; Pain; Prosp | 2001 |