cimetidine has been researched along with Bile Duct Obstruction in 12 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The models of experimental liver dysfunction included bile duct ligation (with sham-operated controls), alpha-naphthylisothiocyanate-induced intrahepatic cholestasis and galactosamine-induced diffuse hepatocellular necrosis." | 7.68 | The effect of liver dysfunction on colchicine pharmacokinetics in the rat. ( Bay, MK; Johnson, RF; Leighton, JA; Maldonado, AL; Schenker, S; Speeg, KV, 1990) |
| " The models of experimental liver dysfunction included bile duct ligation (with sham-operated controls), alpha-naphthylisothiocyanate-induced intrahepatic cholestasis and galactosamine-induced diffuse hepatocellular necrosis." | 3.68 | The effect of liver dysfunction on colchicine pharmacokinetics in the rat. ( Bay, MK; Johnson, RF; Leighton, JA; Maldonado, AL; Schenker, S; Speeg, KV, 1990) |
| "Cholestasis is associated with analgesia." | 1.37 | Two histamine H2 receptor antagonists, zolantidine and cimetidine, modulate nociception in cholestatic rats. ( Hasanein, P, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (66.67) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hasanein, P | 1 |
| Kurata, T | 1 |
| Muraki, Y | 1 |
| Mizutani, H | 1 |
| Iwamoto, T | 1 |
| Okuda, M | 1 |
| Kolts, BE | 1 |
| Langfitt, M | 1 |
| Kodama, O | 1 |
| Takeuchi, H | 1 |
| Ogawa, Y | 1 |
| Ito, N | 1 |
| Tanaka, T | 1 |
| Harada, M | 1 |
| Seikoh, R | 1 |
| Ezaki, H | 1 |
| Paliard, P | 1 |
| Partensky, C | 1 |
| Ding, XZ | 1 |
| Li, H | 1 |
| Xiong, ST | 1 |
| Zhang, SX | 1 |
| Lu, KZ | 1 |
| Shao, JF | 1 |
| Shen, GX | 1 |
| Yang, J | 1 |
| Harrison, AR | 1 |
| Littenberg, G | 1 |
| Goldstein, L | 1 |
| Kaplowitz, N | 1 |
| Lilly, JR | 1 |
| Hitch, DC | 1 |
| Javitt, NB | 1 |
| Züchner, H | 1 |
| Leighton, JA | 1 |
| Bay, MK | 1 |
| Maldonado, AL | 1 |
| Johnson, RF | 1 |
| Schenker, S | 1 |
| Speeg, KV | 1 |
| Namba, S | 1 |
| Clarke, B | 1 |
| Yoong, A | 1 |
1 trial available for cimetidine and Bile Duct Obstruction
| Article | Year |
|---|---|
Pruritus, cimetidine and polycythemia.
Topics: Cholestasis; Cimetidine; Clinical Trials as Topic; Guanidines; Humans; Pruritus | 1979 |
11 other studies available for cimetidine and Bile Duct Obstruction
| Article | Year |
|---|---|
Two histamine H2 receptor antagonists, zolantidine and cimetidine, modulate nociception in cholestatic rats.
Topics: Analgesia; Animals; Benzothiazoles; Cholestasis; Cimetidine; Dimaprit; Disease Models, Animal; Hista | 2011 |
Elevated systemic elimination of cimetidine in rats with acute biliary obstruction: the role of renal organic cation transporter OCT2.
Topics: Acute Disease; Animals; Antiporters; Catecholamine Plasma Membrane Transport Proteins; Cholestasis; | 2010 |
Drugs and the liver.
Topics: Acetaminophen; Adult; Aspirin; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liv | 1984 |
Experimental studies on prophylactic measures against acute gastric mucosal lesion complicated with obstructive jaundice with emphasis on the prophylactic effect of cimetidine.
Topics: Animals; Cholestasis; Cimetidine; Gastric Mucosa; Male; Rats | 1984 |
[Polycystic liver disease with abdominal pain and jaundice treated by two successive "fenestration" procedure (author's transl)].
Topics: Adult; Cholestasis; Cimetidine; Cysts; Guanidines; Humans; Liver Diseases; Male; Postoperative Perio | 1980 |
Effects of cimetidine on IL-2 and T suppressor cell function in rats with obstructive jaundice.
Topics: Adjuvants, Immunologic; Animals; Cholestasis; Cimetidine; Interleukin-2; Male; Random Allocation; Ra | 1994 |
Cimetidine cholestatic jaundice in children.
Topics: Adolescent; Bile Acids and Salts; Bilirubin; Child, Preschool; Cholestasis; Cimetidine; Guanidines; | 1978 |
[Cholestatic hepatosis under Cimetidine].
Topics: Cholestasis; Cimetidine; Gastritis; Guanidines; Humans; Male; Middle Aged | 1977 |
The effect of liver dysfunction on colchicine pharmacokinetics in the rat.
Topics: 1-Naphthylisothiocyanate; Animals; Cholestasis; Cimetidine; Colchicine; Cytochrome P-450 Enzyme Inhi | 1990 |
[Inhibitory effects of omeprazole and cimetidine on the formation of gastric ulcer in rats with obstructive jaundice and acute renal failure].
Topics: Acute Kidney Injury; Animals; Cholestasis; Cimetidine; Gastric Mucosa; Male; Omeprazole; Rats; Rats, | 1988 |
Prolonged cholestasis and cimetidine.
Topics: Cholestasis; Chronic Disease; Cimetidine; Humans; Male; Middle Aged | 1987 |