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cimetidine and Barrett Epithelium

cimetidine has been researched along with Barrett Epithelium in 19 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Research Excerpts

ExcerptRelevanceReference
"This long-term study in a patient with Barrett's esophagus showed 1) that cimetidine can be effective in treating such patients; 2) the prophylactic value of multitherapy as a maintenance regimen, and 3) the importance of careful follow-up."5.27Prolonged cimetidine therapy in ulcerated Barrett's columnar-lined esophagus. ( Avidor, I; Delpre, G; Glanz, I; Kadish, U, 1984)
"Gastric acid secretion in response to a protein meal and to exogenously administered synthetic human gastrin 17-I was measured in patients with Barrett's esophagus, patients with uncomplicated gastroesophageal reflux, and normal age- and sex-matched controls."3.67Elevated gastric acid secretion in patients with Barrett's metaplastic epithelium. ( Levine, DS; Mulholland, MW; Reid, BJ; Rubin, CE, 1989)
"The possibility exists that Barrett's esophagus may be acquired in some instances and congenital in others."2.36Barrett's esophagus. ( Berardi, RS; Devaiah, KA, 1983)
"This long-term study in a patient with Barrett's esophagus showed 1) that cimetidine can be effective in treating such patients; 2) the prophylactic value of multitherapy as a maintenance regimen, and 3) the importance of careful follow-up."1.27Prolonged cimetidine therapy in ulcerated Barrett's columnar-lined esophagus. ( Avidor, I; Delpre, G; Glanz, I; Kadish, U, 1984)
"Gastroesophageal reflux (GER) disease is a common, multifactorial medical condition that may be difficult to treat."1.27A critical review of current medical therapy for gastroesophageal reflux disease. ( Richter, JE, 1986)
"I have reviewed Barrett's esophagus in the light of recent advances."1.26Barrett's esophagus: an old entity rediscovered. ( Mangla, JC, 1981)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199015 (78.95)18.7374
1990's3 (15.79)18.2507
2000's1 (5.26)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wesdorp, IC2
Berardi, RS1
Devaiah, KA1
Delpre, G1
Kadish, U1
Glanz, I1
Avidor, I1
Saltzman, M1
Barwick, K1
McCallum, RW1
Fahrländer, H1
Bartelsman, J1
Schipper, ME1
Tytgat, GN1
Mangla, JC1
Le Rhun, M1
Galmiche, JP1
Hassall, E1
Mascarenhas, MR1
McGowan, KL1
Ruchelli, E1
Athreya, B1
Altschuler, SM1
Todd, JA1
Weston, T1
MacDonald, TM1
Johnston, DA1
Dillon, JF1
Mulholland, MW1
Reid, BJ1
Levine, DS1
Rubin, CE1
Hennessy, TP1
Richter, JE1
Spechler, SJ1
Goyal, RK1
Humphries, TJ1
Cooper, BT1
Barbezat, GO1
Lieberman, DA1
Kerlin, P1
d'Mellow, G1
van Deth, A1

Reviews

5 reviews available for cimetidine and Barrett Epithelium

ArticleYear
Barrett's esophagus.
    Surgery, gynecology & obstetrics, 1983, Volume: 156, Issue:4

    Topics: Adenocarcinoma; Adolescent; Adult; Age Factors; Aged; Animals; Barrett Esophagus; Carcinoma, Squamou

1983
[Is remission of Barrett esophagus possible?].
    Gastroenterologie clinique et biologique, 1994, Volume: 18, Issue:1 Pt 2

    Topics: Antacids; Barrett Esophagus; Bethanechol Compounds; Cimetidine; Drug Therapy, Combination; Gastroeso

1994
Barrett's esophagus: new definitions and approaches in children.
    Journal of pediatric gastroenterology and nutrition, 1993, Volume: 16, Issue:4

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Barrett Esophagus; Child; Child, Preschool; Cimetidine; End

1993
Barrett's oesophagus.
    The British journal of surgery, 1985, Volume: 72, Issue:5

    Topics: Adenocarcinoma; Adolescent; Adult; Barrett Esophagus; Cimetidine; Epithelium; Esophageal Diseases; E

1985
Barrett's esophagus.
    The New England journal of medicine, 1986, Aug-07, Volume: 315, Issue:6

    Topics: Adenocarcinoma; Antacids; Barrett Esophagus; Bethanechol; Bethanechol Compounds; Cimetidine; Epithel

1986

Trials

1 trial available for cimetidine and Barrett Epithelium

ArticleYear
Medical therapy for chronic reflux esophagitis. Long-term follow-up.
    Archives of internal medicine, 1987, Volume: 147, Issue:10

    Topics: Barrett Esophagus; Chronic Disease; Cimetidine; Clinical Trials as Topic; Drug Therapy, Combination;

1987

Other Studies

13 other studies available for cimetidine and Barrett Epithelium

ArticleYear
Treatment of reflux oesophagitis.
    Scandinavian journal of gastroenterology. Supplement, 1982, Volume: 79

    Topics: Alginates; Aluminum Hydroxide; Antacids; Anti-Ulcer Agents; Barrett Esophagus; Bethanechol Compounds

1982
Prolonged cimetidine therapy in ulcerated Barrett's columnar-lined esophagus.
    The American journal of gastroenterology, 1984, Volume: 79, Issue:1

    Topics: Aged; Aluminum Hydroxide; Barrett Esophagus; Cimetidine; Drug Combinations; Drug Therapy, Combinatio

1984
Progression of cimetidine-treated reflux esophagitis to a Barrett's stricture.
    Digestive diseases and sciences, 1982, Volume: 27, Issue:2

    Topics: Aged; Barrett Esophagus; Cimetidine; Esophageal Diseases; Esophageal Stenosis; Esophagitis, Peptic;

1982
[Pathophysiology, clinical aspects and therapy of gastro-esophageal reflux disease].
    Schweizerische medizinische Wochenschrift, 1981, Apr-18, Volume: 111, Issue:16

    Topics: Antacids; Barrett Esophagus; Candidiasis; Cholic Acids; Cimetidine; Diagnosis, Differential; Endosco

1981
Effect of long-term treatment with cimetidine and antacids in Barrett's oesophagus.
    Gut, 1981, Volume: 22, Issue:9

    Topics: Adult; Aged; Antacids; Barrett Esophagus; Cimetidine; Esophageal Diseases; Esophagitis, Peptic; Esop

1981
Barrett's esophagus: an old entity rediscovered.
    Journal of clinical gastroenterology, 1981, Volume: 3, Issue:4

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Barrett Esophagus; Bethanechol Compounds; Biopsy; Child; Ch

1981
Acremonium infection of the esophagus.
    Journal of pediatric gastroenterology and nutrition, 1997, Volume: 24, Issue:3

    Topics: Acremonium; Barrett Esophagus; Child, Preschool; Cimetidine; Connective Tissue Diseases; Esophageal

1997
The prescribing of acid suppressants prior to the endoscopic diagnosis of Barrett's oesophagus and oesophagitis.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:2

    Topics: Antacids; Barrett Esophagus; Cimetidine; Drug Prescriptions; Endoscopy; Esophagitis; Female; Humans;

2001
Elevated gastric acid secretion in patients with Barrett's metaplastic epithelium.
    Digestive diseases and sciences, 1989, Volume: 34, Issue:9

    Topics: Barrett Esophagus; Chronic Disease; Cimetidine; Female; Gastric Acid; Gastric Acidity Determination;

1989
A critical review of current medical therapy for gastroesophageal reflux disease.
    Journal of clinical gastroenterology, 1986, Volume: 8 Suppl 1

    Topics: Alginates; Antacids; Barrett Esophagus; Bethanechol; Bethanechol Compounds; Cimetidine; Gastroesopha

1986
Effects of long-term medical treatment with cimetidine and bethanechol in patients with esophagitis and Barrett's esophagus.
    Journal of clinical gastroenterology, 1987, Volume: 9, Issue:1

    Topics: Adult; Barrett Esophagus; Bethanechol; Bethanechol Compounds; Cimetidine; Esophageal Diseases; Esoph

1987
Treatment of Barrett's esophagus with H2 blockers.
    Journal of clinical gastroenterology, 1987, Volume: 9, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Barrett Esophagus; Cimetidine; Esophageal Diseases; Female; Histamin

1987
Barrett's esophagus: clinical, endoscopic, and histologic spectrum in fifty patients.
    Australian and New Zealand journal of medicine, 1986, Volume: 16, Issue:2

    Topics: Aged; Barrett Esophagus; Cimetidine; Endoscopy; Epithelium; Esophageal Diseases; Esophagus; Female;

1986