cimetidine has been researched along with B16 Melanoma in 3 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
| Excerpt | Relevance | Reference |
|---|---|---|
| "B16-C3 murine melanoma, A375P human melanotic melanoma, and C32 human amelanotic melanoma cells were incubated in the presence of (0-4 mM) H2-antagonists, ranitidine and cimetidine." | 3.68 | The effects of histamine H2 receptor antagonists on melanogenesis and cellular proliferation in melanoma cells in culture. ( Uçar, K, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Szincsák, N | 1 |
| Hegyesi, H | 1 |
| Hunyadi, J | 1 |
| Martin, G | 1 |
| Lázár-Molnár, E | 1 |
| Kovács, P | 1 |
| Rivera, E | 1 |
| Falus, A | 1 |
| Juhász, I | 1 |
| Tomita, K | 1 |
| Nakamura, E | 1 |
| Okabe, S | 1 |
| Uçar, K | 1 |
3 other studies available for cimetidine and B16 Melanoma
| Article | Year |
|---|---|
Cimetidine and a tamoxifen derivate reduce tumour formation in SCID mice xenotransplanted with a human melanoma cell line.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Autocrine Communication; Cell Division; Cim | 2002 |
Histamine regulates growth of malignant melanoma implants via H2 receptors in mice.
Topics: Administration, Oral; Animals; Cell Line, Tumor; Cell Proliferation; Cimetidine; Dose-Response Relat | 2005 |
The effects of histamine H2 receptor antagonists on melanogenesis and cellular proliferation in melanoma cells in culture.
Topics: Animals; Cell Division; Cell Line; Cimetidine; Dose-Response Relationship, Drug; Humans; Kinetics; M | 1991 |