cimetidine and Aura
cimetidine has been researched along with Aura in 7 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acetaminophen metabolism and clearance after a single 1 gm oral dose of the drug was investigated in 12 healthy men, six of whom were cigarette smokers, and in six men who were receiving anticonvulsant drugs for epilepsy." | 3.67 | Determinants of acetaminophen metabolism: effect of inducers and inhibitors of drug metabolism on acetaminophen's metabolic pathways. ( Attwood, J; Birkett, DJ; Miners, JO, 1984) |
| "Neurocysticercosis is the most important parasitic infection of the nervous system in countries of the third world." | 2.38 | Neurocysticercosis. An introduction with special emphasis on new developments in pharmacotherapy. ( Overbosch, D, 1992) |
| ", ip) indicate that the liver is the primary site of biotransformation of the compound, suggesting that both 22a and its metabolite(s) are active, compensating probably low bioavailability of the parent molecule." | 1.43 | Design, physico-chemical properties and biological evaluation of some new N-[(phenoxy)alkyl]- and N-{2-[2-(phenoxy)ethoxy]ethyl}aminoalkanols as anticonvulsant agents. ( Bednarski, M; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pękala, E; Powroźnik, B; Słoczyńska, K; Walczak, M; Waszkielewicz, AM; Żesławska, E, 2016) |
| "Cimetidine-related neurotoxicity may be characterized by signs of affective dysfunction, toxic delusional state and/or delirium, confusion and/or amnestic signs, coma, epileptic phenomena and focal neurological signs." | 1.27 | Cimetidine neurotoxicity. EEG and behaviour aspects. ( Kamphuisen, HA; Van Sweden, B, 1984) |
| "Cimetidine can cause significant changes in phenytoin serum levels which may be manifested clinically." | 1.27 | Effect of cimetidine on phenytoin serum levels. ( Breland, BD; Jordan, JE; Mishra, SK; Salem, RB, 1983) |
Research
Studies (7)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (71.43) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Waszkielewicz, AM | 1 |
| Gunia-Krzyżak, A | 1 |
| Powroźnik, B | 1 |
| Słoczyńska, K | 1 |
| Pękala, E | 1 |
| Walczak, M | 1 |
| Bednarski, M | 1 |
| Żesławska, E | 1 |
| Nitek, W | 1 |
| Marona, H | 1 |
| Phillips, P | 1 |
| Hansky, J | 1 |
| Van Sweden, B | 1 |
| Kamphuisen, HA | 1 |
| Miners, JO | 1 |
| Attwood, J | 1 |
| Birkett, DJ | 1 |
| Hetzel, DJ | 1 |
| Bochner, F | 1 |
| Hallpike, JF | 1 |
| Shearman, DJ | 1 |
| Hann, CS | 1 |
| Salem, RB | 1 |
| Breland, BD | 1 |
| Mishra, SK | 1 |
| Jordan, JE | 1 |
| Overbosch, D | 1 |
Reviews
1 review available for cimetidine and Aura
| Article | Year |
|---|---|
Neurocysticercosis. An introduction with special emphasis on new developments in pharmacotherapy.
Topics: Albendazole; Central Nervous System Diseases; Cimetidine; Cysticercosis; Diagnosis, Differential; Di | 1992 |
Other Studies
6 other studies available for cimetidine and Aura
| Article | Year |
|---|---|
Design, physico-chemical properties and biological evaluation of some new N-[(phenoxy)alkyl]- and N-{2-[2-(phenoxy)ethoxy]ethyl}aminoalkanols as anticonvulsant agents.
Topics: Amino Alcohols; Animals; Anticonvulsants; Chemistry, Physical; Dose-Response Relationship, Drug; Dru | 2016 |
Phenytoin toxicity secondary to cimetidine administration.
Topics: Aged; Cimetidine; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Peptic Ulc | 1984 |
Cimetidine neurotoxicity. EEG and behaviour aspects.
Topics: Brain; Brain Diseases; Cimetidine; Confusion; Delusions; Electroencephalography; Epilepsy; Female; H | 1984 |
Determinants of acetaminophen metabolism: effect of inducers and inhibitors of drug metabolism on acetaminophen's metabolic pathways.
Topics: Acetaminophen; Administration, Oral; Adult; Anticonvulsants; Biotransformation; Cimetidine; Drug Int | 1984 |
Cimetidine interaction with phenytoin.
Topics: Adult; Cimetidine; Drug Interactions; Epilepsy; Guanidines; Humans; Middle Aged; Phenytoin | 1981 |
Effect of cimetidine on phenytoin serum levels.
Topics: Cimetidine; Drug Synergism; Epilepsy; Guanidines; Humans; Male; Phenytoin | 1983 |