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cimetidine and Arthritis

cimetidine has been researched along with Arthritis in 8 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Arthritis: Acute or chronic inflammation of JOINTS.

Research Excerpts

ExcerptRelevanceReference
"A case report is presented of a patient having a history of gouty arthritic attacks who suffered similar attacks subsequent to receiving cimetidine and ranitidine."7.67Gout-like arthritis following cimetidine and ranitidine. ( Einarson, TR; Goldstein, JE; MacNay, KR; Turchet, EN, 1985)
"A randomised crossover study was performed in subjects with rheumatoid arthritis (or other arthropathies) to investigate if any alteration in the steady pharmacokinetics of the NSAID piroxicam (a drug which is extensively metabolised via cytochrome P450) or its major metabolites occurred as a result of coadministering either cimetidine or nizatidine."5.07The consequences of H2 receptor antagonist--piroxicam coadministration in patients with joint disorders. ( Howden, CW; Kelman, AW; McGill, PE; Milligan, PA; Whiting, B, 1993)
"A case report is presented of a patient having a history of gouty arthritic attacks who suffered similar attacks subsequent to receiving cimetidine and ranitidine."3.67Gout-like arthritis following cimetidine and ranitidine. ( Einarson, TR; Goldstein, JE; MacNay, KR; Turchet, EN, 1985)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19907 (87.50)18.7374
1990's1 (12.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Manger, BF1
Stix, R1
Beck, AL1
Kalden, JR1
Al-Haboubi, HA2
Zeitlin, IJ2
Croker, JR1
Cotton, PB1
Boyle, AC1
Kinsella, P1
Milligan, PA1
McGill, PE1
Howden, CW1
Kelman, AW1
Whiting, B1
Welch, RW1
Bentch, HL1
Harris, SC1
Davies, J1
Collins, AJ1
Dixon, SA1
Einarson, TR1
Turchet, EN1
Goldstein, JE1
MacNay, KR1

Trials

3 trials available for cimetidine and Arthritis

ArticleYear
The consequences of H2 receptor antagonist--piroxicam coadministration in patients with joint disorders.
    European journal of clinical pharmacology, 1993, Volume: 45, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Arthritis; Cimetidine; Drug Interactions; Female; Histamine H2 Antag

1993
Reduction of aspirin-induced gastrointestinal bleeding with cimetidine.
    Gastroenterology, 1978, Volume: 74, Issue:2 Pt 2

    Topics: Arthritis; Aspirin; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Gastric Juice; Gastro

1978
The influence of cimetidine on peptic ulcer in patients with arthritis taking anti-inflammatory drugs.
    British journal of rheumatology, 1986, Volume: 25, Issue:1

    Topics: Analgesics; Antacids; Anti-Inflammatory Agents; Arthritis; Cimetidine; Drug Evaluation; Drug Utiliza

1986

Other Studies

5 other studies available for cimetidine and Arthritis

ArticleYear
Cimetidine and psoriatic arthritis.
    Archives of dermatology, 1983, Volume: 119, Issue:10

    Topics: Arthritis; Cimetidine; Guanidines; Humans; Psoriasis

1983
The actions of cimetidine hydrochloride and mepyramine maleate in rat adjuvant arthritis.
    European journal of pharmacology, 1982, Feb-26, Volume: 78, Issue:2

    Topics: Aminopyridines; Animals; Arthritis; Arthritis, Experimental; Cimetidine; Guanidines; Male; Pyrilamin

1982
Cimetidine for peptic ulcer in patients with arthritis.
    Annals of the rheumatic diseases, 1980, Volume: 39, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis; Cimetidine; Endoscopy; Female; Guanidines; Humans;

1980
The actions of cimetidine, mepyramine, indomethacin and aprotinin (Trasylol) on the inflammatory response in adjuvant rats [proceedings].
    British journal of pharmacology, 1979, Volume: 67, Issue:3

    Topics: Aminopyridines; Animals; Aprotinin; Arthritis; Arthritis, Experimental; Cimetidine; Guanidines; Indo

1979
Gout-like arthritis following cimetidine and ranitidine.
    Drug intelligence & clinical pharmacy, 1985, Volume: 19, Issue:3

    Topics: Adult; Arthritis; Cimetidine; Gout; Humans; Male; Ranitidine

1985