cimetidine has been researched along with Arthritis, Degenerative in 4 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty-three patients chronically ingesting plain aspirin or nonsteroidal antiinflammatory drugs, who had endoscopically proven solitary or multiple gastric ulcers, were treated for eight weeks with cimetidine and antacids." | 9.06 | Persistence of gastric ulcers caused by plain aspirin or nonsteroidal antiinflammatory agents in patients treated with a combination of cimetidine, antacids, and enteric-coated aspirin. ( Calzada, R; Dhar, R; Jaszewski, R, 1989) |
| "Steady state piroxicam plasma samples from 85 patients suffering from osteoarthritis of the hip and/or the knee, and treated with piroxicam 20 mg daily for at least four weeks, were obtained." | 7.68 | Free plasma concentrations of piroxicam in patients with osteoarthritis: relation to age, sex and efficacy. ( Hundal, O; Rugstad, HE, 1993) |
| "Twenty-three patients chronically ingesting plain aspirin or nonsteroidal antiinflammatory drugs, who had endoscopically proven solitary or multiple gastric ulcers, were treated for eight weeks with cimetidine and antacids." | 5.06 | Persistence of gastric ulcers caused by plain aspirin or nonsteroidal antiinflammatory agents in patients treated with a combination of cimetidine, antacids, and enteric-coated aspirin. ( Calzada, R; Dhar, R; Jaszewski, R, 1989) |
| "Steady state piroxicam plasma samples from 85 patients suffering from osteoarthritis of the hip and/or the knee, and treated with piroxicam 20 mg daily for at least four weeks, were obtained." | 3.68 | Free plasma concentrations of piroxicam in patients with osteoarthritis: relation to age, sex and efficacy. ( Hundal, O; Rugstad, HE, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rugstad, HE | 2 |
| Giercksky, KE | 1 |
| Husby, G | 1 |
| Holme, I | 1 |
| Hundal, O | 1 |
| Jaszewski, R | 1 |
| Calzada, R | 1 |
| Dhar, R | 1 |
| Roth, SH | 1 |
| Bennett, RE | 1 |
| Mitchell, CS | 1 |
| Hartman, RJ | 1 |
3 trials available for cimetidine and Arthritis, Degenerative
| Article | Year |
|---|---|
Effect of cimetidine on gastrointestinal symptoms in patients taking nonsteroidal anti-inflammatory drugs. A large double-blind placebo controlled study.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cimetidine; Double-Blind Me | 1994 |
Persistence of gastric ulcers caused by plain aspirin or nonsteroidal antiinflammatory agents in patients treated with a combination of cimetidine, antacids, and enteric-coated aspirin.
Topics: Antacids; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cimetidine; Drug Therapy, Combination; G | 1989 |
Cimetidine therapy in nonsteroidal anti-inflammatory drug gastropathy. Double-blind long-term evaluation.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cimetidine; Clinical Tri | 1987 |
1 other study available for cimetidine and Arthritis, Degenerative
| Article | Year |
|---|---|
Free plasma concentrations of piroxicam in patients with osteoarthritis: relation to age, sex and efficacy.
Topics: Aged; Aged, 80 and over; Aging; Cimetidine; Drug Therapy, Combination; Female; Humans; Male; Middle | 1993 |